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Source: Epilepsy Curr

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Total 106 results found since Jan 2013.

Bacopa monnieri for disorders affecting brain: Current perspectives
Curr Top Med Chem. 2022 Jan 19. doi: 10.2174/1568026622666220119111538. Online ahead of print.ABSTRACTBacopa monnieri (BM) is of immense therapeutic potential in today's world. This review is aimed to project the beneficial role of BM in disorders affecting the brain, including Alzheimer's disease, Parkinson's disease, stroke, epilepsy and depression. The active constituents and metabolites responsible for the effects of BM could be bacoside A and B, bacopaside I and II, bacopasaponin C, betulinic acid, asiatic acid, loliolide, ebelin lactone and quercetin. The mechanistic role of BM in brain disorders might be related to ...
Source: Epilepsy Curr - January 19, 2022 Category: Neurology Authors: Adithya Vinod S Sathianarayanan Anju Elizabath Babu Prashant Sadanandan None Athira K V Baskar Venkidasamy Source Type: research

A Review on the Arylpiperazine Derivatives as Potential Therapeutics for the Treatment of Various Neurological Disorders
Curr Drug Targets. 2022 Jan 17. doi: 10.2174/1389450123666220117104038. Online ahead of print.ABSTRACTNeurological disorders are disease conditions related to the neurons and central nervous system (CNS). Any kind of structural, electrical, biochemical and functional abnormalities in neurons can lead to various types of disorders like Alzheimer's disease (AD), depression, Parkinson's disease (PD), epilepsy, stroke, etc. Currently available medicines are symptomatic and do not treat the disease state. Thus, novel CNS active agents with the potential of complete treatment of an illness are highly desired. A range of small or...
Source: Epilepsy Curr - March 21, 2022 Category: Neurology Authors: Bhupinder Kumar Naveen Kumar Amandeep Thakur Vijay Kumar Rakesh Kumar Vinod Kumar Source Type: research

Current Trends in the Animal Models for Screening of Nootropic Agents
CONCLUSION: Since a variety of etiologies can affect the cognitive processes, hence a nootropic agent may be screened in a variety of disease models. The most widely used and appropriate method to assess cognition would be by combining the behavioral and biochemical assays so that a more comprehensive profile about the nootropic effects of a drug can be elicited.PMID:35469584 | DOI:10.2174/2772432817666220425121323
Source: Epilepsy Curr - April 26, 2022 Category: Neurology Authors: Shubhima Grover Seema Jain Source Type: research