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Total 310 results found since Jan 2013.

Single-center experience of endovascular treatment for patients with progressive posterior circulation cerebral infarction exceeding 24 h
CONCLUSION: In patients with progressive posterior circulation cerebral infarction caused by vertebral basilar artery occlusion, ET is effective and safe even if the time from onset to puncture exceeds 24 h.PMID:37719319 | PMC:PMC10505061 | DOI:10.2478/abm-2023-0046
Source: Biomed Res - September 18, 2023 Category: Research Authors: Guangfeng Zhao Xiongjun He Yajie Liu Liang Zhang Kaifeng Li Source Type: research

Status of Hypertension Control in Urban Slums of Central India: A community Health Worker-Based Two-Year Follow-Up
CONCLUSION: We found about six of every ten individuals with HTN were on treatment, and about four were optimally controlled. These findings provide a benchmark for NPCDCS, in terms of achievable goals within short periods of follow-up.PMID:37694241 | PMC:PMC10492608 | DOI:10.4103/abr.abr_266_22
Source: Biomed Res - September 11, 2023 Category: Research Authors: Abhijit Pakhare Anuja Lahiri Neelesh Shrivastava Krishna N Subba Vaishnavi Veera Durga Kurra Ankur Joshi Shubham Atal Sagar Khadanga Rajnish Joshi Source Type: research

Ketone body 3-hydroxybutyrate elevates cardiac output through peripheral vasorelaxation and enhanced cardiac contractility
Basic Res Cardiol. 2023 Sep 9;118(1):37. doi: 10.1007/s00395-023-01008-y.ABSTRACTThe ketone body 3-hydroxybutyrate (3-OHB) increases cardiac output and myocardial perfusion without affecting blood pressure in humans, but the cardiovascular sites of action remain obscure. Here, we test the hypothesis in rats that 3-OHB acts directly on the heart to increase cardiac contractility and directly on blood vessels to lower systemic vascular resistance. We investigate effects of 3-OHB on (a) in vivo hemodynamics using echocardiography and invasive blood pressure measurements, (b) isolated perfused hearts in Langendorff systems, an...
Source: Biomed Res - September 9, 2023 Category: Research Authors: Casper Homilius Jacob Marthinsen Seefeldt Julie S ørensen Axelsen Tina Myhre Pedersen Trine Monberg S ørensen Roni Nielsen Henrik Wiggers Jakob Hansen Vladimir V Matchkov Hans Erik B øtker Ebbe Boedtkjer Source Type: research

Retracted: Significance of Edaravone Combined with Emotion Management Model in Promoting the Recovery Process and Improving Negative Psychology in Patients with Type 2 Diabetes Mellitus Combined with Stroke
Biomed Res Int. 2023 Aug 30;2023:9845187. doi: 10.1155/2023/9845187. eCollection 2023.ABSTRACT[This retracts the article DOI: 10.1155/2022/8099997.].PMID:37680301 | PMC:PMC10482530 | DOI:10.1155/2023/9845187
Source: Biomed Res - September 8, 2023 Category: Research Authors: BioMed Research International Source Type: research

The Polyherbal Functional Ingredient Containing Ginger, Chinese Date, and Wood Ear Mushroom Protects against Dementia following Metabolic Syndrome
This study was performed to test this hypothesis and to explore the underlying mechanism. Male Wistar rats weighing 180-220 g were induced metabolic syndrome (MetS) with a 16-week high-carbohydrate high-fat diet (HCHF) feeding. The rats with MetS characteristics were orally administered GCJ at various doses (GCJ100, GCJ200, and GCJ300 mg kg-1 BW) 21 days pre-induction and 21 days post-induction of reperfusion injury (I/R) at the right middle cerebral artery (MCAO). Memory was evaluated every 7 days during the study period. At the end of the study, neuron density, AChE activity, and the expressions of eNOS, BDNF, and pERK/E...
Source: Biomed Res - August 11, 2023 Category: Research Authors: Thuntiva Nakyam Jintanaporn Wattanathorn Wipawee Thukham-Mee Supaporn Muchimapura Source Type: research

Retracted: A Bibliometric Analysis for Global Trends and Full View of the Autophagy in Ischemic Stroke from 2006 to 2022
Biomed Res Int. 2023 Aug 2;2023:9873891. doi: 10.1155/2023/9873891. eCollection 2023.ABSTRACT[This retracts the article DOI: 10.1155/2022/7799243.].PMID:37564138 | PMC:PMC10412287 | DOI:10.1155/2023/9873891
Source: Biomed Res - August 11, 2023 Category: Research Authors: BioMed Research International Source Type: research

Retracted: Knockdown of PVT1 Exerts Neuroprotective Effects against Ischemic Stroke Injury through Regulation of miR-214/Gpx1 Axis
Biomed Res Int. 2023 Jul 12;2023:9828104. doi: 10.1155/2023/9828104. eCollection 2023.ABSTRACT[This retracts the article DOI: 10.1155/2022/1393177.].PMID:37475796 | PMC:PMC10356302 | DOI:10.1155/2023/9828104
Source: Biomed Res - July 21, 2023 Category: Research Authors: BioMed Research International Source Type: research

TRPC Channels Activated by G Protein-Coupled Receptors Drive Ca < sup > 2+ < /sup > Dysregulation Leading to Secondary Brain Injury in the Mouse Model
Transl Stroke Res. 2023 Jul 18. doi: 10.1007/s12975-023-01173-1. Online ahead of print.ABSTRACTCanonical transient receptor potential (TRPC) non-selective cation channels, particularly those assembled with TRPC3, TRPC6, and TRPC7 subunits, are coupled to Gαq-type G protein-coupled receptors for the major classes of excitatory neurotransmitters. Sustained activation of this TRPC channel-based pathophysiological signaling hub in neurons and glia likely contributes to prodigious excitotoxicity-driven secondary brain injury expansion. This was investigated in mouse models with selective Trpc gene knockout (KO). In adult cereb...
Source: Biomed Res - July 18, 2023 Category: Research Authors: Jasneet Parmar Georg von Jonquieres Nagarajesh Gorlamandala Brandon Chung Amanda J Craig Jeremy L Pinyon Lutz Birnbaumer Matthias Klugmann Andrew J Moorhouse John M Power Gary D Housley Source Type: research