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Source: Cancer Control
Vaccination: Cancer Vaccines
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Total 661 results found since Jan 2013.
Age-dependent impairment in antibody responses elicited by a homologous CoronaVac booster dose
Sci Transl Med. 2023 Feb 15;15(683):eade6023. doi: 10.1126/scitranslmed.ade6023. Epub 2023 Feb 15.ABSTRACTThe emergence of the SARS-CoV-2 Omicron sublineages resulted in increased transmission rates and reduced protection from vaccines. To counteract these effects, multiple booster strategies were used in different countries, although data comparing their efficiency in improving protective immunity remain sparse, especially among vulnerable populations, including older adults. The inactivated CoronaVac vaccine was among the most widely distributed vaccine worldwide and was essential in the early control of SARS-CoV-2-relat...
Source: Cancer Control - February 15, 2023 Category: Cancer & Oncology Authors: Bruno Andraus Filardi Valter Silva Monteiro Pedro Vellosa Schwartzmann Vivian do Prado Martins Luis Eduardo Rosa Zucca Gabriela Crispim Baiocchi Amyn A Malik Julio Silva Anne M Hahn Nicholas F G Chen Kien Pham Eddy P érez-Then Marija Miric Vivian Brache Source Type: research
"If People Were Told About the Cancer, They'd Want to Get Vaccinated": Knowledge, Attitudes, and Beliefs About HPV Vaccination Among Mid-Adult Men
This study aimed to identify knowledge, attitudes, and beliefs (KABs) about HPV and HPV vaccination among newly eligible mid-adult men, for whom uptake in adolescence and younger adulthood remains suboptimal. We conducted six virtual focus groups (N = 34 participants) with unvaccinated men aged 27 to 45 living in Southern California's Inland Empire. Data were systematically analyzed to identify emergent themes using the rigorous and accelerated data reduction technique. The sample of men was diverse (79% Hispanic, non-Hispanic Black, Asian, or mixed race/ethnicity; 26% gay or bisexual) and captured participants from across...
Source: Cancer Control - February 14, 2023 Category: Cancer & Oncology Authors: Raneem A Alaraj Brandon Brown Andrea N Polonijo Source Type: research
Acceptability and readiness to promote human papillomavirus vaccination at ages 9-10 years: A pilot study among rural North Carolina clinics
Res Sq. 2023 Jan 30:rs.3.rs-2326137. doi: 10.21203/rs.3.rs-2326137/v1. Preprint.ABSTRACTWhile 9-valent human papillomavirus vaccination (HPV-9) is approved by the U.S. Food and Drug Administration for use in adolescents as young as age 9, providers typically recommend it at ages 11-12 per Centers for Disease Control and Prevention recommendations. Studies suggest that recommending HPV-9 at 9 or 10 years of age could increase up-to-date vaccination by age 13, which could benefit rural populations with reduced access to primary health care and lower HPV-9 coverage than urban areas. This pilot study aimed to assess the feasib...
Source: Cancer Control - February 13, 2023 Category: Cancer & Oncology Authors: Nadja Vielot Robyn M Lane Kaitlyn Loefstedt Jennifer Cunningham Jason Everson Eli Tiller Sallie Patel Jennifer Smith Source Type: research
No association of malignant B-cell non-Hodgkin lymphomas with ipsilateral SARS-CoV-2 vaccination
CONCLUSIONS: Together, we found no evidence that the current SARS-CoV-2 vaccines could serve as a trigger for lymphomagenesis in the draining lymph node areas of the deltoid region used for vaccination.PMID:36775947 | DOI:10.1002/cam4.5687
Source: Cancer Control - February 13, 2023 Category: Cancer & Oncology Authors: Luise Victoria Claa ß Patrick Mayr Lisa Paschold Thomas Weber Denis Terziev Bertram Jehs Richard Brill Johannes Dober Bruno M ärkl Claudia Wickenhauser Piotr Czapiewski Martin Trepel Rainer Claus Mascha Binder Source Type: research
Engineered Norovirus-Derived Nanoparticles as a Plug-and-Play Cancer Vaccine Platform
In conclusion, the Nov-S-Catcher003 system is a promising delivery platform for facilitating the development of NP-based cancer vaccines.PMID:36779845 | DOI:10.1021/acsnano.2c08840
Source: Cancer Control - February 13, 2023 Category: Cancer & Oncology Authors: Peng Zheng Ying Yang Yuting Fu Jinrong He Yongmao Hu Xiao Zheng Biao Duan Mengzhen Wang Qingwen Liu Weiran Li Duo Li Ying Yang Zhongqian Yang Xu Yang Weiwei Huang Yanbing Ma Source Type: research
Behavioral and Social Drivers of COVID-19 Vaccination in the United States, August-November 2021
CONCLUSIONS: This nationally representative survey found that COVID-19 vaccine uptake was most strongly associated with greater anticipated regret, risk perception, and confidence in vaccine safety and importance, followed by vaccination requirements and social norms. Interventions that leverage these social and behavioral drivers of vaccination have the potential to increase COVID-19 vaccine uptake and could be considered for other vaccine introductions.PMID:36775756 | DOI:10.1016/j.amepre.2023.01.014
Source: Cancer Control - February 12, 2023 Category: Cancer & Oncology Authors: Kimberly E Bonner Kushagra Vashist Neetu S Abad Jennifer L Kriss Lu Meng James T Lee Elisabeth Wilhelm Peng-Jun Lu Rosalind J Carter Kwanza Boone Brittney Baack Nina B Masters Debora Weiss Carla Black Qian Huang Sitaram Vangala Christina Albertin Peter G Source Type: research
Effectiveness and feasibility of three types of parent reminders to increase adolescent human papillomavirus (HPV) vaccination
Prev Med. 2023 Feb 9:107448. doi: 10.1016/j.ypmed.2023.107448. Online ahead of print.ABSTRACTParent reminders have produced modest improvements in human papillomavirus (HPV) vaccination among adolescents. However, little prior research has compared the effectiveness and feasibility of different HPV reminder types in resource-limited settings. We conducted a quasi-experimental study (2016-2017) to evaluate the effectiveness of three parent reminder types (mailed letters, robocalls, text messages) on next-dose HPV vaccine receipt among 12-year-olds in a large Federally Qualified Health Center in Los Angeles County. Six clini...
Source: Cancer Control - February 11, 2023 Category: Cancer & Oncology Authors: Beth A Glenn Catherine M Crespi Alison K Herrmann Narissa J Nonzee R N Debra L Rosen Christine L Park M D Gina Johnson M S L Cindy Chang Rita Singhal Victoria M Taylor Roshan Bastani Source Type: research
A qualitative study of behavioral and social drivers of COVID-19 vaccine confidence and uptake among unvaccinated Americans in the US April-May 2021
DISCUSSION: Vaccine confidence communication strategies should address individual concerns, describe the benefits of COVID-19 vaccination, and highlight evolving science using factural and neutral presentations of information to foster trust.PMID:36763680 | DOI:10.1371/journal.pone.0281497
Source: Cancer Control - February 10, 2023 Category: Cancer & Oncology Authors: Neetu Abad Seth D Messinger Qian Huang Megan A Hendrich Nataly Johanson Helen Fisun Zachary Lewis Elisabeth Wilhelm Brittney Baack Kimberly E Bonner Rosemarie Kobau Noel T Brewer Source Type: research
Molecular Bottlebrushes for Immunostimulatory CpG ODN Delivery: Relationship among Cation Density, Complex Formation Ability, and Cytotoxicity
Biomacromolecules. 2023 Feb 10. doi: 10.1021/acs.biomac.2c01348. Online ahead of print.ABSTRACTArtificially designed short single-stranded DNA sequences containing unmethylated CG (CpG ODNs) are agonists for toll-like receptor 9 (TLR9); thus, they have great potential as vaccine adjuvants for cancer immunotherapy and preventing infectious diseases. To deliver effectively CpG ODNs into cells bearing TLR9, nanoparticle polyion complexes of cationic polymers that are able to ingest multiple CpG ODN molecules have been developed; however, their structures and synthesized polycations are hard to control and bioincompatible, res...
Source: Cancer Control - February 10, 2023 Category: Cancer & Oncology Authors: Shin Takano Yusuke Miyashima Shota Fujii Kazuo Sakurai Source Type: research
Kinetics of SARS-CoV-2 neutralizing antibodies in Omicron breakthrough cases with inactivated vaccination: Role in inferring the history and duration of infection
CONCLUSION: Our study demonstrates that the NAb titers of Omicron BA.2 variant breakthrough cases are higher than in the post-immunized group. The difference in NAb levels could be used to identify cases of breakthrough infection from the post-immunized population in an outbreak epidemic.PMID:36761738 | PMC:PMC9902649 | DOI:10.3389/fimmu.2023.1083523
Source: Cancer Control - February 10, 2023 Category: Cancer & Oncology Authors: Aidibai Simayi Chuchu Li Cong Chen Yin Wang Chen Dong Hua Tian Xiaoxiao Kong Lu Zhou Jiefu Peng Shihan Zhang Fengcai Zhu Jianli Hu Ke Xu Hui Jin Huafeng Fan Changjun Bao Liguo Zhu Source Type: research
Design, synthesis and immunological evaluation of monophosphoryl lipid A derivatives as adjuvants for a RBD-hFc based SARS-CoV-2 vaccine
RSC Med Chem. 2022 Oct 14;14(1):47-55. doi: 10.1039/d2md00298a. eCollection 2023 Jan 25.ABSTRACTToll-like receptor 4 (TLR4) is a reliable target for the development of vaccine adjuvants. To identify novel TLR4 ligands with improved immunological properties for use as adjuvants for a RBD-hFc based SARS-CoV-2 vaccine, herein, natural E. coli monophosphoryl lipid A (MPLA) and nine of its derivatives were designed and synthesized. Immunological evaluation showed that compounds 1, 3, 5 and 7 exhibited comparative or better adjuvant activity than clinically used Al adjuvants, and are expected to be a promising platform for the d...
Source: Cancer Control - February 10, 2023 Category: Cancer & Oncology Authors: Shiwei Su Liqing Chen Menglan Yang Dan Liang Bixia Ke Zhongqiu Liu Changwen Ke Guochao Liao Liang Liu Xiang Luo Source Type: research
Immunization of Mice with Virus-Like Vesicles of Kaposi Sarcoma-Associated Herpesvirus Reveals a Role for Antibodies Targeting ORF4 in Activating Complement-Mediated Neutralization
J Virol. 2023 Feb 9:e0160022. doi: 10.1128/jvi.01600-22. Online ahead of print.ABSTRACTInfection by Kaposi sarcoma-associated herpesvirus (KSHV) can cause severe consequences, such as cancers and lymphoproliferative diseases. Whole inactivated viruses (WIV) with chemically destroyed genetic materials have been used as antigens in several licensed vaccines. During KSHV productive replication, virus-like vesicles (VLVs) that lack capsids and viral genomes are generated along with virions. Here, we investigated the immunogenicity of KSHV VLVs produced from a viral mutant that was defective in capsid formation and DNA packagin...
Source: Cancer Control - February 9, 2023 Category: Cancer & Oncology Authors: Alex K Lam Romin Roshan Wendell Miley Nazzarena Labo James Zhen Andrew P Kurland Celine Cheng Haigen Huang Pu-Lin Teng Claire Harelson Danyang Gong Ying K Tam Caius G Radu Marta Epeldegui Jeffrey R Johnson Z Hong Zhou Denise Whitby Ting-Ting Wu Source Type: research
Cancer and COVID-19 vaccines on Twitter: The voice and vaccine attitude of cancer community
J Health Commun. 2023 Feb 8:1-14. doi: 10.1080/10810730.2023.2168800. Online ahead of print.ABSTRACTWe investigate social media discourses on the relationship between cancer and COVID-19 vaccines focusing on the key textual topics, themes reflecting the voice of cancer community, authors who contribute to the discourse, and valence toward vaccines. We analyzed 6,427 tweets about cancer and COVID-19 vaccines, posted from when vaccines were approved in the U.S. (December 2020) to the February 2022. We mixed quantitative text mining, manual coding and statistical analysis, and inductive qualitative thematic analysis. Nearly 1...
Source: Cancer Control - February 9, 2023 Category: Cancer & Oncology Authors: Jungmi Jun Karen Wickersham Ali Zain Rachel Ford Nanlan Zhang Carl Ciccarelli Sei-Hill Kim Chen Liang Source Type: research
Prevalence of High-Risk Human Papillomavirus in Cervical Intraepithelial Neoplasia in the Pre-Vaccine Era - China, 2017-2018
China CDC Wkly. 2022 Dec 2;4(48):1083-1087. doi: 10.46234/ccdcw2022.218.ABSTRACTWHAT IS ALREADY KNOWN ABOUT THIS TOPIC?: Human papillomavirus (HPV) type-specific strategies play a key role in the prevention of cervical intraepithelial neoplasia (CIN), but evidence on the HPV type-specific prevalence in CIN is limited.WHAT IS ADDED BY THIS REPORT?: This multicentric study estimates the prevalence of high-risk HPV types in CIN cases and the associations of HPV infection patterns with high-grade CIN in China in 2017-2018.WHAT ARE THE IMPLICATIONS FOR PUBLIC HEALTH PRACTICE?: Population-based prevention strategies should give ...
Source: Cancer Control - February 8, 2023 Category: Cancer & Oncology Authors: Heling Bao Weihong Chen Xiaosong Zhang Hui Bi Yun Zhao Liwen Fang Shu Cong Feng Tan Linhong Wang Source Type: research
A comprehensive screening for hepatitis B and C as an effective means of cancer prevention and as a prerequisite for elimination of chronic viral hepatitis - Data and comments on a discussion
Dtsch Med Wochenschr. 2023 Feb;148(4):175-182. doi: 10.1055/a-1972-4118. Epub 2023 Feb 7.ABSTRACTSince October 2021 in Germany all people with a statutory health insurance aged 35 and older have the right to be tested once for hepatitis B and C in a general preventative examination, regardless of specific risk-factors. This is a milestone on the way of eliminating these infections and also a great contribution to cancer prevention.In the USA the Centers of Disease Control and Prevention in April 2020 recommended a one-time screening for all adults aged 18 and older in addition to testing people with known risk-factors, bec...
Source: Cancer Control - February 7, 2023 Category: Cancer & Oncology Authors: Ingmar Wolffram Source Type: research
