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Source: Cancer Control
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Total 161 results found since Jan 2013.
Study Protocol and Baseline Characteristics of Randomized Trial for Evaluating Secondary Prevention Efficacy of Combination Therapy-Statin and Eicosapentaenoic Acid: RESPECT-EPA, The Combination of a Randomized Control Trial and an Observational Biomarker Study
CONCLUSIONS: After this study is completed, we will have further evidence on whether a highly purified EPA is effective in reducing cardiovascular events for secondary prevention or not, as well as whether if EPA/AA ratio is a predictor for future cardiovascular events.PMID:36372250 | DOI:10.1016/j.ahj.2022.11.008
Source: Cancer Control - November 13, 2022 Category: Cancer & Oncology Authors: Yuji Nishizaki Katsumi Miyauchi Hiroshi Iwata Teruo Inoue Atsushi Hirayama Kazuo Kimura Yukio Ozaki Toyoaki Murohara Kenji Ueshima Yoshihiro Kuwabara Sachiko Tanaka-Mizuno Naotake Yanagisawa Tosiya Sato Hiroyuki Daida Source Type: research
Resiliency intervention for patient-caregiver dyads in the Neuro-ICU: Study protocol for a single-blind randomized clinical trial
DISCUSSION: If successful, we plan to test RT in a large-scale, multisite hybrid effectiveness-implementation study in Neuro-ICUs across the country. Enhancing psychosocial supports for patients and families could improve health outcomes, healthcare efficiency, and the culture of these units.PMID:36368480 | DOI:10.1016/j.cct.2022.106998
Source: Cancer Control - November 11, 2022 Category: Cancer & Oncology Authors: Ana-Maria Vranceanu Emily C Woodworth Millan R Kanaya Sarah Bannon Ryan A Mace Heena Manglani Brooke A Duarte Christina L Rush Nathaniel R Choukas Ellie A Briskin Joshua Cohen Robert Parker Eric Macklin Ethan Lester Lara Traeger Jonathan Rosand Karon M Ko Source Type: research
Association Between Aromatase Inhibitors and Myocardial Infarction Morbidity in Women With Breast Cancer: A Meta-Analysis of Observational Studies
CONCLUSION: Based on real-world data, AIs may be a safe treatment route for patients with estrogen receptor-positive breast cancer and those with a history of CVD. AIs caused a major decrease in MI in patients without CVD history. However, more in-depth investigations are needed to explore the association between AI use and the incidence of MI in the treatment of estrogen receptor-positive breast cancer.PMID:36346929 | DOI:10.1177/10732748221132512
Source: Cancer Control - November 8, 2022 Category: Cancer & Oncology Authors: Jing-Chao Sun Ze-Fan Sun Chao-Jie He Chang-Lin Zhai Gang Qian Source Type: research
The effect of voice training interventions on patients with oropharyngeal dysphagia: a systematic review
CONCLUSIONS: In general, statistically significant positive therapy effects were found. Voice training improves the oral and pharyngeal stages of swallowing in patients with neurological causes of dysphagia, such as stroke, and in patients with non-neurological causes of dysphagia, such as head and neck cancer. However, the current literature is limited and further primary research is required to provide more evidence to support voice training intervention in dysphagia. Future studies could further refine the content of voice training interventions, increase the number of patients enrolled, assess the long-term effects of ...
Source: Cancer Control - November 7, 2022 Category: Cancer & Oncology Authors: Chunyan Niu Wenyan Zhou Haifang Wang Yingying Zhang Jianzheng Cai Nini Lu Yalan Wang Source Type: research
Admission Rates, Time Trends, Risk Factors, and Outcomes of Ischemic and Hemorrhagic Stroke From German Nationwide Data
DISCUSSION: Despite recent advances in acute stroke care over the last decade, the percentage of stroke hospitalizations resulting in death remained unchanged. Further research is needed to determine how best to optimize stroke care pathways for multimorbid patients.PMID:36332988 | DOI:10.1212/WNL.0000000000201259
Source: Cancer Control - November 4, 2022 Category: Cancer & Oncology Authors: Dearbhla M Kelly Jannik Feld Peter M Rothwell Holger Reinecke Jeanette Koeppe Source Type: research
Trimethylamine N-Oxide as a potential risk factor for non-communicable diseases: A systematic review
CONCLUSION: There is a dose-response relationship between TMAO levels and NCDs progression. Therefore, it can be studied as a therapeutic target or prognostic biomarker for dealing with NCDs.PMID:36330632 | DOI:10.2174/1871530323666221103120410
Source: Cancer Control - November 4, 2022 Category: Cancer & Oncology Authors: Zahra Hoseini Tavassol Hanieh-Sadat Ejtahed Bagher Larijani Shirin Hasani-Ranjbar Source Type: research
Evaluation of a Novel Synthetic Peptide Derived from Cytolytic Mycotoxin Candidalysin
Toxins (Basel). 2022 Oct 11;14(10):696. doi: 10.3390/toxins14100696.ABSTRACTThe importance of neuroinflammation in neurology is becoming increasingly apparent. In addition to neuroinflammatory diseases such as multiple sclerosis, the role of neuroinflammation has been identified in many non-inflammatory neurological disorders such as stroke, epilepsy, and cancer. The immune response within the brain involves the presence of CNS resident cells; mainly glial cells, such as microglia, the CNS resident macrophages. We evaluated the peptide Ca-MAP1 bioinspired on the C. albicans immature cytolytic toxin candidalysin to develop ...
Source: Cancer Control - October 26, 2022 Category: Cancer & Oncology Authors: Pedro Henrique de Oliveira Cardoso Ana Paula de Ara újo Boleti Patr ícia Souza E Silva Lincoln Takashi Hota Mukoyama Alexya Sandim Guindo Luiz Filipe Ramalho Nunes de Moraes Caio Fernando Ramalho de Oliveira Maria Ligia Rodrigues Macedo Cristiano Marcel Source Type: research
Can mental practice adjunct in the recovery of motor function in the upper limbs after stroke? A systematic review and meta-analysis
CONCLUSION: Current evidence does not support the use of the mental practice to increase the recovery of the upper limb after stroke, although the evidence is conflicting for some aspects of the technique.PMID:36267434 | PMC:PMC9578308 | DOI:10.4103/bc.bc_28_22
Source: Cancer Control - October 21, 2022 Category: Cancer & Oncology Authors: Danielle Aprigio Juliana Bittencourt Maria Ramim Victor Marinho Igor Brauns Isabelle Fernandes Pedro Ribeiro Bruna Velasques Ana Catarina Alves E Silva Source Type: research
Therapeutic efficacy of matrix metalloproteinase-12 suppression on neurological recovery after ischemic stroke: Optimal treatment timing and duration
The objectives of this study were to (1) determine the effect of MMP-12 suppression by shRNA-mediated gene silencing on neurological/functional recovery, (2) establish the optimal timing of MMP-12shRNA treatment that provides maximum therapeutic benefit, (3) compare the effectiveness of acute versus chronic MMP-12 suppression, and (4) evaluate potential sex-related differences in treatment outcomes. Young male and female Sprague-Dawley rats were subjected to transient middle cerebral artery occlusion and reperfusion. Cohorts of rats were administered either MMP-12shRNA or scrambled shRNA sequence (control) expressing plasm...
Source: Cancer Control - October 21, 2022 Category: Cancer & Oncology Authors: Siva Reddy Challa Koteswara Rao Nalamolu Casimir A Fornal Billy C Wang Ryan C Martin Elsa A Olson Ammar L Ujjainwala David M Pinson Jeffrey D Klopfenstein Krishna Kumar Veeravalli Source Type: research
Incident Cardiovascular Diseases Among Survivors of High-Risk Stage II-III Colorectal Cancer: A Cluster-Wide Cohort Study
CONCLUSIONS: Exposure to adjuvant fluoropyrimidine-based chemotherapy was associated with an increased risk of CVD among survivors of high-risk stage II-III CRC. Cardiovascular risk monitoring of this group throughout cancer survivorship is advisable.PMID:36240841 | DOI:10.6004/jnccn.2022.7042
Source: Cancer Control - October 14, 2022 Category: Cancer & Oncology Authors: Shing Fung Lee Pui Lam Yip Balamurugan A Vellayappan Cheng Ean Chee Lea Choung Wong Eric Yuk-Fai Wan Esther Wai-Yin Chan Chak-Fei Lee Francis Ann-Shing Lee Miguel Angel Luque-Fernandez Source Type: research
Sex- and age-specific all-cause mortality in insomnia with hypnotics: Findings from Japan multi-institutional Collaborative Cohort Study
CONCLUSIONS: Our study revealed sex-age specific associations between hypnotic use and all-cause mortality.PMID:36240602 | DOI:10.1016/j.sleep.2022.09.020
Source: Cancer Control - October 14, 2022 Category: Cancer & Oncology Authors: Rintaro Sogawa Chisato Shimanoe Keitaro Tanaka Megumi Hara Yuichiro Nishida Takuma Furukawa Mako Nagayoshi Asahi Hishida Yoko Kubo Yasufumi Kato Isao Oze Hidemi Ito Yohko Nakamura Miho Kusakabe Shiroh Tanoue Chihaya Koriyama Sadao Suzuki Takahiro Otani Da Source Type: research
Influenza Vaccination and Risk of Ischemic Stroke: A Population-Based Case-Control Study
DISCUSSION: Results are compatible with a moderate protective effect of influenza vaccine on IS appearing early after vaccination. The finding that a reduced risk was also observed in pre-epidemic periods suggests that either the "protection" is not totally linked to prevention of influenza infection, or it may be partly explained by unmeasured confounding factors.PMID:36240087 | DOI:10.1212/WNL.0000000000201123
Source: Cancer Control - October 14, 2022 Category: Cancer & Oncology Authors: Sara Rodr íguez-Martín Diana Barreira-Hern ández Miguel Gil Alberto Garc ía-Lledó Laura Izquierdo-Esteban Francisco Jose De Abajo Source Type: research
Role of Serum Homocysteine and Outcome in Patients With Traumatic Brain Injury
Conclusion The study concluded that patients who had suffered from a TBI had significantly higher serum Hcy levels. Furthermore, the study highlighted that the patients with the worst outcomes had more severe hyperhomocysteinemia (HHcy) than those with better outcomes. Moreover, patients with low GOS scores were more likely to have HHcy.PMID:36237797 | PMC:PMC9548089 | DOI:10.7759/cureus.28968
Source: Cancer Control - October 14, 2022 Category: Cancer & Oncology Authors: Humayoun Amini Hewad Hewadmal Sayed Farhad Rasuli Chowdhury S Shahriar Abdul Fattah Hariharan Kavanoor Sridhar Marjan Khan Sadaf Bhat Abdul Subhan Talpur Laila Tul Qadar Source Type: research
Related factors based on non-targeted metabolomics methods in minor ischaemic stroke
CONCLUSION: Increased levels of lactic acid, pyruvate, and TMAO may be related to the pathophysiological changes in the minor ischaemic stroke population. High blood pressure, a lack of physical activity, smoking, and increased TMAO level were the influencing factors for the occurrence of minor ischaemic stroke. The serum metabolite TMAO may be associated with MS occurrence.PMID:36237188 | PMC:PMC9552842 | DOI:10.3389/fendo.2022.952918
Source: Cancer Control - October 14, 2022 Category: Cancer & Oncology Authors: Chen Chen Xiaoyuan Qiao Jianyong Guo Ting Yang Min Wang Yipeng Ma Shuhe Zhao Ling Ding Hong Liu Jintao Wang Source Type: research
