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Specialty: Cancer & Oncology
Source: Cancer Control

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Total 161 results found since Jan 2013.

Association between self-reported gingival bleeding and prevalent hypertension among adults in a cross-sectional study in Zhejiang province
Conclusion: Frequent gingival bleeding was positively associated with prevalent hypertension among men.PMID:35981987 | DOI:10.3760/cma.j.cn112338-20210922-00744
Source: Cancer Control - August 18, 2022 Category: Cancer & Oncology Authors: H Wang L L Chen Y Q Guan Y Cao D Shen K X Xie X Y Zhang C M Wang P Pei Y Guo M Yu L M Chen Liming Li Source Type: research

Neuroprotective effects of tannic acid in the postischemic brain via direct chelation of Zn < sup > 2 < /sup >
Anim Cells Syst (Seoul). 2022 Aug 19;26(4):183-191. doi: 10.1080/19768354.2022.2113915. eCollection 2022.ABSTRACTTannic acid (TA) is a polyphenolic compound that exerts protective effects under pathological conditions. The diverse mechanisms of TA can exert beneficial anti-oxidative, anti-inflammatory, and anti-cancer effects. Herein, we reported that TA affords robust neuroprotection in an animal model of stroke (transient middle cerebral artery occlusion; tMCAO) and exhibits Zn2+-chelating and anti-oxidative effects in primary cortical neurons. Following tMCAO induction, intravenous administration of TA (5 mg/kg) suppres...
Source: Cancer Control - September 1, 2022 Category: Cancer & Oncology Authors: Seung Woo Kim Da Bin Kim Hong Seok Kim Source Type: research

Recent advances in drug delivery and targeting to the brain
J Control Release. 2022 Aug 31:S0168-3659(22)00574-0. doi: 10.1016/j.jconrel.2022.08.051. Online ahead of print.ABSTRACTOur body keeps separating the toxic chemicals in the blood from the brain. A significant number of drugs do not enter the central nervous system (CNS) due to the blood-brain barrier (BBB). Certain diseases, such as tumor growth and stroke, are known to increase the permeability of the BBB. However, the heterogeneity of this permeation makes it difficult and unpredictable to transport drugs to the brain. In recent years, research has been directed toward increasing drug penetration inside the brain, and na...
Source: Cancer Control - September 3, 2022 Category: Cancer & Oncology Authors: Bharti Sethi Virender Kumar Kalika Mahato Donald W Coulter Ram I Mahato Source Type: research

Is the rule of halves in hypertension valid uniformly across India? A cross-sectional analysis of national family health survey-4 data
CONCLUSION: The rule of halves of India shows that the National Programme for Prevention and Control of Cancer, Diabetes, Cardiovascular Diseases, and Stroke has made relatively good progress with the detection of hypertension and achieving BP control among those on treatment. However, with three-fourth of known hypertensives not availing treatment, more dividends from the detection of hypertension efforts could be realized. The program needs to especially focus on ensuring the treatment for those detected with hypertension.PMID:36149103 | DOI:10.4103/ijph.ijph_2143_21
Source: Cancer Control - September 23, 2022 Category: Cancer & Oncology Authors: Mohd Maroof Nafis Faizi Pruthu Thekkur Sonika Raj Sonu Goel Source Type: research

Understanding knowledge of hypertension among affected individuals in low-Income (B40) communities in Malaysia: The RESPOND study
CONCLUSION: This study provides reassurance that individuals with hypertension in disadvantaged communities in Malaysia have a relatively good understanding of hypertension. Further research should explore the challenges they face on their therapeutic journeys.PMID:36169064
Source: Cancer Control - September 28, 2022 Category: Cancer & Oncology Authors: F Ariffin M R Isa M N Nafiza M Y Mazapuspavina A M Fadhlina B Palafox M McKee Source Type: research

Cigarette Smoking Among US Adults With Selected Chronic Diseases Associated With Smoking, 2010-2019
CONCLUSION: Overall, smoking prevalence remains high and relatively unchanged among people with chronic diseases associated with smoking, even as the overall prevalence of cigarette smoking in the US continues to decrease. The lack of progress in smoking cessation among adults with chronic diseases associated with smoking suggests that access, promotion, and integration of cessation treatment across the continuum of health care (ie, oncology, pulmonology, and cardiology settings) may be important in the success of smoking cessation in this population.PMID:36173703 | DOI:10.5888/pcd19.220086
Source: Cancer Control - September 29, 2022 Category: Cancer & Oncology Authors: Caitlin G Loretan Monica E Cornelius Ahmed Jamal Yiling J Cheng David M Homa Source Type: research

Enhanced autophagy interacting proteins negatively correlated with the activation of apoptosis-related caspase family proteins after focal ischemic stroke of young rats
CONCLUSIONS: Collectively, the present results suggest that the the reduced levels of neuronal death after CIR in young rats were closely related to enhanced levels of autophagy and reduced levels of pro-apoptosis in neurons.PMID:36171540 | DOI:10.1186/s12868-022-00740-w
Source: Cancer Control - September 28, 2022 Category: Cancer & Oncology Authors: Jie Wang Zihao Xia Peng Sheng Mengmeng Shen Lidong Ding Dezhi Liu Bing Chun Yan Source Type: research

Chronic Oxidative Stress as a Marker of Long-term Radiation-Induced Cardiovascular Outcomes in Breast Cancer
We examined associations of biomarkers of oxidative stress (myeloperoxidase, growth differentiation factor-15, 8-hydroxy-2'-deoxyguanosine [8-OH-dG], placental growth factor), cardiac injury (troponin I, cystatin-C), inflammation (interleukin-6, C-reactive protein), and myocardial fibrosis (transforming growth factor-ß) with long-term RICVD in breast cancer (BC) survivors. We conducted a nested case-control study within the Women's Health Initiative of postmenopausal women with incident BC stages I-III, who received radiation and had pre- and post-BC diagnosis serum samples. Cases (n = 55) were defined as developing incid...
Source: Cancer Control - September 30, 2022 Category: Cancer & Oncology Authors: Alexi Vasbinder Richard K Cheng Susan R Heckbert Hilaire Thompson Oleg Zaslavksy Rowan T Chlebowski Aladdin H Shadyab Lisa Johnson Jean Wactawski-Wende Gretchen Wells Rachel Yung Lisa Warsinger Martin Electra D Paskett Kerryn Reding Source Type: research

Role of Serum Homocysteine and Outcome in Patients With Traumatic Brain Injury
Conclusion The study concluded that patients who had suffered from a TBI had significantly higher serum Hcy levels. Furthermore, the study highlighted that the patients with the worst outcomes had more severe hyperhomocysteinemia (HHcy) than those with better outcomes. Moreover, patients with low GOS scores were more likely to have HHcy.PMID:36237797 | PMC:PMC9548089 | DOI:10.7759/cureus.28968
Source: Cancer Control - October 14, 2022 Category: Cancer & Oncology Authors: Humayoun Amini Hewad Hewadmal Sayed Farhad Rasuli Chowdhury S Shahriar Abdul Fattah Hariharan Kavanoor Sridhar Marjan Khan Sadaf Bhat Abdul Subhan Talpur Laila Tul Qadar Source Type: research

Incident Cardiovascular Diseases Among Survivors of High-Risk Stage II-III Colorectal Cancer: A Cluster-Wide Cohort Study
CONCLUSIONS: Exposure to adjuvant fluoropyrimidine-based chemotherapy was associated with an increased risk of CVD among survivors of high-risk stage II-III CRC. Cardiovascular risk monitoring of this group throughout cancer survivorship is advisable.PMID:36240841 | DOI:10.6004/jnccn.2022.7042
Source: Cancer Control - October 14, 2022 Category: Cancer & Oncology Authors: Shing Fung Lee Pui Lam Yip Balamurugan A Vellayappan Cheng Ean Chee Lea Choung Wong Eric Yuk-Fai Wan Esther Wai-Yin Chan Chak-Fei Lee Francis Ann-Shing Lee Miguel Angel Luque-Fernandez Source Type: research

Sex- and age-specific all-cause mortality in insomnia with hypnotics: Findings from Japan multi-institutional Collaborative Cohort Study
CONCLUSIONS: Our study revealed sex-age specific associations between hypnotic use and all-cause mortality.PMID:36240602 | DOI:10.1016/j.sleep.2022.09.020
Source: Cancer Control - October 14, 2022 Category: Cancer & Oncology Authors: Rintaro Sogawa Chisato Shimanoe Keitaro Tanaka Megumi Hara Yuichiro Nishida Takuma Furukawa Mako Nagayoshi Asahi Hishida Yoko Kubo Yasufumi Kato Isao Oze Hidemi Ito Yohko Nakamura Miho Kusakabe Shiroh Tanoue Chihaya Koriyama Sadao Suzuki Takahiro Otani Da Source Type: research

Evaluation of a Novel Synthetic Peptide Derived from Cytolytic Mycotoxin Candidalysin
Toxins (Basel). 2022 Oct 11;14(10):696. doi: 10.3390/toxins14100696.ABSTRACTThe importance of neuroinflammation in neurology is becoming increasingly apparent. In addition to neuroinflammatory diseases such as multiple sclerosis, the role of neuroinflammation has been identified in many non-inflammatory neurological disorders such as stroke, epilepsy, and cancer. The immune response within the brain involves the presence of CNS resident cells; mainly glial cells, such as microglia, the CNS resident macrophages. We evaluated the peptide Ca-MAP1 bioinspired on the C. albicans immature cytolytic toxin candidalysin to develop ...
Source: Cancer Control - October 26, 2022 Category: Cancer & Oncology Authors: Pedro Henrique de Oliveira Cardoso Ana Paula de Ara újo Boleti Patr ícia Souza E Silva Lincoln Takashi Hota Mukoyama Alexya Sandim Guindo Luiz Filipe Ramalho Nunes de Moraes Caio Fernando Ramalho de Oliveira Maria Ligia Rodrigues Macedo Cristiano Marcel Source Type: research

Trimethylamine N-Oxide as a potential risk factor for non-communicable diseases: A systematic review
CONCLUSION: There is a dose-response relationship between TMAO levels and NCDs progression. Therefore, it can be studied as a therapeutic target or prognostic biomarker for dealing with NCDs.PMID:36330632 | DOI:10.2174/1871530323666221103120410
Source: Cancer Control - November 4, 2022 Category: Cancer & Oncology Authors: Zahra Hoseini Tavassol Hanieh-Sadat Ejtahed Bagher Larijani Shirin Hasani-Ranjbar Source Type: research

The effect of voice training interventions on patients with oropharyngeal dysphagia: a systematic review
CONCLUSIONS: In general, statistically significant positive therapy effects were found. Voice training improves the oral and pharyngeal stages of swallowing in patients with neurological causes of dysphagia, such as stroke, and in patients with non-neurological causes of dysphagia, such as head and neck cancer. However, the current literature is limited and further primary research is required to provide more evidence to support voice training intervention in dysphagia. Future studies could further refine the content of voice training interventions, increase the number of patients enrolled, assess the long-term effects of ...
Source: Cancer Control - November 7, 2022 Category: Cancer & Oncology Authors: Chunyan Niu Wenyan Zhou Haifang Wang Yingying Zhang Jianzheng Cai Nini Lu Yalan Wang Source Type: research