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Specialty: Cancer & Oncology
Source: Cancer Control
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Total 161 results found since Jan 2013.
Influenza Vaccination and Risk of Ischemic Stroke: A Population-Based Case-Control Study
DISCUSSION: Results are compatible with a moderate protective effect of influenza vaccine on IS appearing early after vaccination. The finding that a reduced risk was also observed in pre-epidemic periods suggests that either the "protection" is not totally linked to prevention of influenza infection, or it may be partly explained by unmeasured confounding factors.PMID:36240087 | DOI:10.1212/WNL.0000000000201123
Source: Cancer Control - October 14, 2022 Category: Cancer & Oncology Authors: Sara Rodr íguez-Martín Diana Barreira-Hern ández Miguel Gil Alberto Garc ía-Lledó Laura Izquierdo-Esteban Francisco Jose De Abajo Source Type: research
The effects of Baduanjin on physical function, daily living activities and quality of life in patients with stroke: a systematic review and meta-analysis
CONCLUSIONS: Baduanjin is probably an effective rehabilitation method to improve balance, motor, trunk, neurological functions, daily living activities, and quality of life in stroke patients. However, the result of Baduanjin in improving walking function is unstable, and further high-quality randomized controlled trials are needed to confirm the results.PMID:37555455 | DOI:10.1080/10749357.2023.2238433
Source: Cancer Control - August 9, 2023 Category: Cancer & Oncology Authors: Lirong Wei Yun Liu Yanan Wang Jiping Bian Zhengyang Song Xiaofeng Liu Shen Wang Source Type: research
Chronic cerebral hypoperfusion and blood-brain barrier disruption in uninjured brain areas of rhesus monkeys subjected to transient ischemic stroke
J Cereb Blood Flow Metab. 2022 Feb 9:271678X221078065. doi: 10.1177/0271678X221078065. Online ahead of print.ABSTRACTBlood-brain barrier (BBB) disruption is a pivotal pathophysiological process in ischemic stroke. Although temporal changes in BBB permeability during the acute phase have been widely studied, little is known about the chronic phase of cerebrovascular changes that may have a large impact on the long-term outcome. Therefore, this study was aimed to measure cerebral vascular abnormalities using CT perfusion in nine rhesus monkeys subjected to transient middle cerebral artery occlusion (tMCAO) for ≥1 year (MCA...
Source: Cancer Control - February 9, 2022 Category: Cancer & Oncology Authors: Yingqian Zhang Bangcheng Zhao Qi Lai Qinxi Li Xun Tang Yinbing Zhang Zhixiang Pan Qiang Gao Zhihui Zhong Source Type: research
Effectiveness of an individualized home-based physical activity program in surgery-free non-endarterectomized asymptomatic stroke patients: a study protocol for the PACAPh interventional randomized trial
This study has been approved by the National Ethics Committee (IDRCB:2019-A01543-54/SI:19.06.21.40640). ClinicalTrials.gov NCT04053166.PMID:35164816 | DOI:10.1186/s13063-022-06061-x
Source: Cancer Control - February 15, 2022 Category: Cancer & Oncology Authors: Mathilde Mura Emeraude Rivoire Leila Dehina-Khenniche Mich èle Weiss-Gayet B énédicte Chazaud Camille Faes Philippe Connes Anne Long Chantal L Rytz Pauline Mury Lidia Delrieu Etienne Gouraud Marine Bordet Nellie Della Schiava Patrick Lermusiaux Matthie Source Type: research
Influence of hospital capabilities and prehospital time on outcomes of thrombectomy for stroke in Japan from 2013 to 2016
Sci Rep. 2022 Feb 28;12(1):3252. doi: 10.1038/s41598-022-06074-1.ABSTRACTTo determine whether increasing thrombectomy-capable hospitals with moderate comprehensive stroke center (CSC) capabilities is a valid alternative to centralization of those with high CSC capabilities. This retrospective, nationwide, observational study used data from the J-ASPECT database linked to national emergency medical service (EMS) records, captured during 2013-2016. We compared the influence of mechanical thrombectomy (MT) use, the CSC score, and the total EMS response time on the modified Rankin Scale score at discharge among patients with a...
Source: Cancer Control - March 1, 2022 Category: Cancer & Oncology Authors: Ai Kurogi Daisuke Onozuka Akihito Hagihara Kunihiro Nishimura Akiko Kada Manabu Hasegawa Takahiro Higashi Takanari Kitazono Tsuyoshi Ohta Nobuyuki Sakai Hajime Arai Susumu Miyamoto Tetsuya Sakamoto Koji Iihara J-ASPECT Study Collaborators Source Type: research
Therapeutic efficacy of matrix metalloproteinase-12 suppression on neurological recovery after ischemic stroke: Optimal treatment timing and duration
The objectives of this study were to (1) determine the effect of MMP-12 suppression by shRNA-mediated gene silencing on neurological/functional recovery, (2) establish the optimal timing of MMP-12shRNA treatment that provides maximum therapeutic benefit, (3) compare the effectiveness of acute versus chronic MMP-12 suppression, and (4) evaluate potential sex-related differences in treatment outcomes. Young male and female Sprague-Dawley rats were subjected to transient middle cerebral artery occlusion and reperfusion. Cohorts of rats were administered either MMP-12shRNA or scrambled shRNA sequence (control) expressing plasm...
Source: Cancer Control - October 21, 2022 Category: Cancer & Oncology Authors: Siva Reddy Challa Koteswara Rao Nalamolu Casimir A Fornal Billy C Wang Ryan C Martin Elsa A Olson Ammar L Ujjainwala David M Pinson Jeffrey D Klopfenstein Krishna Kumar Veeravalli Source Type: research
Bioinformatic analysis and clinical diagnostic value of hsa_circ_0004099 in acute ischemic stroke
This study investigates the expression and effect of hsa_circ_0004099 in acute ischemic stroke (AIS). We conducted a case-controlled study that included 40 patients with AIS within 24 hours and 40 healthy subjects during the same period as a control group. Differentially expressed circular RNAs (circRNAs) were obtained using GEO2R, and the expression of hsa_circ_0004099 was verified using RT-PCR. Correlation analysis of the National Institutes of Health Stroke Scale (NIHSS) disease severity score and ischemic time with hsa_circ_0004099 expression levels was also performed. The receiver operating characteristic (ROC) curve ...
Source: Cancer Control - November 18, 2022 Category: Cancer & Oncology Authors: Jiqing Zheng Shuiming Luo Yaobin Long Source Type: research
Identification of ligustrazine-based analogs of piperlongumine as potential anti-ischemic stroke agents
Fitoterapia. 2022 Dec 20:105398. doi: 10.1016/j.fitote.2022.105398. Online ahead of print.ABSTRACTPiper longum has a specific aroma and spicy taste. In addition to edible value, current studies have shown that piper longum also has pharmacological activities such as anti-platelet aggregation, anti-inflammation, anti-cancer, anti-diabetes and anti-depression. Piperlongumine is an alkaloid isolated from Piper longum. Based on our previous studies, four Piperlongumine analogs were synthesized, and their anti-platelet aggregation activities were evaluated. Among them, compound 8 has the strongest anti-platelet aggregation acti...
Source: Cancer Control - December 23, 2022 Category: Cancer & Oncology Authors: Tan Lijuan Cao Xiaolu Wan Xin He Yuying Lan Xi Yang Xiliang Wang Ting Min Zhenli Zou Yu Source Type: research
Identification of cell death-related biomarkers and immune infiltration in ischemic stroke between male and female patients
CONCLUSION: These findings contribute to a better knowledge of immune cell infiltration and their corresponding molecular mechanisms of cell death and offer distinct clinically relevant biological targets for IS patients of different genders.PMID:37435058 | PMC:PMC10332266 | DOI:10.3389/fimmu.2023.1164742
Source: Cancer Control - July 12, 2023 Category: Cancer & Oncology Authors: Wenli Chen Yuanfang Chen Liting Wu Yue Gao Hangju Zhu Ye Li Xinyu Ji Ziyi Wang Wen Wang Lei Han Baoli Zhu Hongxing Wang Ming Xu Source Type: research
ACSL4 contributes to ferroptosis-mediated rhabdomyolysis in exertional heat stroke
CONCLUSIONS: These findings demonstrate an important role of ACSL4 in mediating ferroptosis activation in the development of RM following EHS and suggest that targeting ACSL4 may represent a novel therapeutic strategy to limit the skeletal muscle cell death and prevent RM after EHS.PMID:35243801 | DOI:10.1002/jcsm.12953
Source: Cancer Control - March 4, 2022 Category: Cancer & Oncology Authors: Sixiao He Ru Li Yanmei Peng Ziqing Wang Junhao Huang Hongen Meng Junxia Min Fudi Wang Qiang Ma Source Type: research
Deep learning-based classification of DSA image sequences of patients with acute ischemic stroke
CONCLUSION: Our deep learning-based approach to thrombus identification in DSA sequences yielded high accuracy on our single-center test data set. External validation is now required to investigate the generalizability of our method. As demonstrated, using this new approach may help reduce the incident risk of overlooking thrombi during thrombectomy in the future.PMID:35604489 | DOI:10.1007/s11548-022-02654-8
Source: Cancer Control - May 23, 2022 Category: Cancer & Oncology Authors: Benjamin J Mittmann Michael Braun Frank Runck Bernd Schmitz Thuy N Tran Amine Yamlahi Lena Maier-Hein Alfred M Franz Source Type: research
Endovascular therapy for acute ischemic stroke in patients with active malignancy: a meta-analysis with trial sequential analysis
CONCLUSION: Although a quarter of patients with active malignancy and AIS regained functional independence, physicians and patients should consider whether to apply EVT in patients with active malignancy.PMID:36163348 | DOI:10.1136/jnis-2022-019489
Source: Cancer Control - September 26, 2022 Category: Cancer & Oncology Authors: Hong-Jie Jhou Li-Yu Yang Po-Huang Chen Cho-Hao Lee Source Type: research
Assessment of National Program for Prevention and Control of Cancer, Diabetes, CVD and Stroke (NPCDCS): An observational study in rural Jaipur, Rajasthan
CONCLUSION: The study concludes that the implementation of NPCDCS program activities is not in synch with the health staff awareness level. IEC activities were deficient and no work was done for adoption of behavioural change and healthy lifestyle. Actual cases of hypertension were more while cases of diabetes were less than the reported cases found on cross-check survey.PMID:36387714 | PMC:PMC9648218 | DOI:10.4103/jfmpc.jfmpc_2281_21
Source: Cancer Control - November 17, 2022 Category: Cancer & Oncology Authors: Sadhana Meena Monika Rathore Ajay Gupta Pragya Kumawat Arpit Singh Source Type: research
Lost individual income due to severe health events: life-course perspective in the Northern Finland Birth Cohort 1966
CONCLUSIONS: Stroke and heart attack but not cancer have exogenous deleterious effects on individual economy, independently of early-life factors. The effects accelerate by time. Negative income trend in control men shows that severe health events do not explain all decrease in income.PMID:36040214 | DOI:10.1093/eurpub/ckac110
Source: Cancer Control - August 30, 2022 Category: Cancer & Oncology Authors: Ina Rissanen Iiro Nerg Leena Ala-Mursula Marko Korhonen Source Type: research
Left Atrial Appendage Occlusion in Patients With Atrial Fibrillation and Cancer
CONCLUSIONS: Within our cohort, LAAO in cancer patients was achieved with good procedural success and offered a reduction in stroke at no increased bleeding risk similar to noncancer patients.PMID:37144110 | PMC:PMC10152198 | DOI:10.1016/j.jaccao.2022.10.016
Source: Cancer Control - May 5, 2023 Category: Cancer & Oncology Authors: Samuel A Shabtaie Nicholas Y Tan Robert C Ward Bradley R Lewis Eric H Yang David R Holmes Joerg Herrmann Source Type: research
