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Source: The Keio Journal of Medicine
Therapy: Gene Therapy
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Total 59 results found since Jan 2013.
Developing mRNA for Therapy
Keio J Med. 2022;71(1):31. doi: 10.2302/kjm.71-001-ABST.ABSTRACTMessenger RNA was discovered in 1961 and it took 60 years until the first mRNA became FDA-approved product in the form of COVID-19 mRNA vaccine. During those years a lot of progress has been made by hundreds of scientists. It was 1978 when the first-time isolated mRNA delivered into mammalian cells produced the encoded protein. In vitro transcription introduced in 1984 made it possible to generate any desired mRNA from the encoding plasmid using phage RNA polymerases. In the early 90s mRNA was used for therapy as well as vaccine against infectious diseases and...
Source: The Keio Journal of Medicine - March 28, 2022 Category: Universities & Medical Training Authors: Katalin Karik รณ Source Type: research
