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Total 106 results found since Jan 2013.

Never before has it been more exciting and important to be a neurologist
What are the current trends and hot topics in neurology? The increasing insights into the genetics and molecular bases of neurological disorders open new perspectives for specific and personalized treatments. This is evidenced most dramatically by the antisense therapy for spinal muscular atrophy. Promising neurological research currently targets neurodegenerative diseases such as amyotrophic lateral sclerosis, Parkinson’s disease, Duchenne muscular atrophy, or Huntington’s disease. Likewise, brain-machine interfaces and neuroprosthetics offer huge potential. Never before has it been more important and more exciting to...
Source: BioMed Central Blog - December 9, 2019 Category: General Medicine Authors: Victoria Hentschke Tags: Uncategorized Source Type: blogs

Innovations, new strategies and surprising twists in Neurology: captured in new journal Neurological Research and Practice
What are the current hot topics in neurology, what do you anticipate will be the challenges and trends in the future within the field? Neurology is such a rapidly moving field that it is impossible to anticipate what the new trends will be. We were frequently proven wrong with our predictions in the past, while completely unexpected developments happened and new avenues were opened. One thing however is for sure: There will be numerous innovations, new strategies, surprising twists and turns, and within the new journal Neurological Research and Practice we try to capture some of them. What are your research interests and w...
Source: BioMed Central Blog - October 1, 2018 Category: General Medicine Authors: Victoria Hentschke Tags: Biology Medicine Open Access Publishing Neurological Research and Practice Source Type: blogs

More to science: working in Business Management
What is your scientific background? I was conferred my PhD in Neuroscience from the Georgetown University Medical Center (GUMC) Interdisciplinary Program in Neuroscience (IPN). I studied central nervous system trauma in rodent models of contusive spinal cord injury. Judy Lytle My thesis centered on a specific type of progenitor cell, and its role in post-injury adult spinal cord tissue. I worked to characterize this cell population’s proliferative capabilities after injury, its ability to become neural cells in the post-injury environment, and tested various growth factors to attempt to recapitulate the cell populationâ€...
Source: BioMed Central Blog - February 27, 2017 Category: Journals (General) Authors: Dana Berry Tags: Biology Health Medicine #moretoscience careers early career researchers PhD Science > Careers Source Type: blogs

December blogs digest: the health benefits of nuts, sequencing the Iberian lynx genome, the importance of pets and more
How can we measure health behavior theories mathematically? William Riley looks at whether Social Cognitive Theory (SCT) could be expressed mathematically. He reports on his article published in Translational Behavioral Medicine in which he and co-authors developed a dynamic computational model for SCT. Magnesium deficiency and its multiple health outcomes Getting enough magnesium in your diet? A study published in BMC Medicine last month found that increased dietary magnesium is associated with a reduced risk of heart failure, stroke, diabetes, and all-cause mortality. The study was the largest of its kind to date, using ...
Source: BioMed Central Blog - January 6, 2017 Category: Journals (General) Authors: Davy Falkner Tags: Biology Health Medicine Open Access blogs digest Source Type: blogs

Citation bias favoring positive clinical trials
While there is still progress to be made on this front, the development of clinical trial registries such as ClinicalTrials.gov and the EU Clinical Trials Register, together with policies mandating the use of these resources, have given the scientific community the tools needed to largely solve this problem. Unfortunately, far less attention has been given to the question of how best to use research data after they have been made publicly available. PubMed currently includes more than 26 million citations. With such an enormous number of available articles to choose from, it is often easy to find individual studies which s...
Source: BioMed Central Blog - September 28, 2016 Category: Journals (General) Authors: Christopher Jones Tags: Medical Evidence Uncategorized citation clinical trials Source Type: blogs

Secondary prevention after ischaemic stroke: the ASPIRE-S study
Conclusion: This prospective multi-centre survey of IS patients demonstrated a high prevalence of remaining modifiable risk factors at 6 months post stroke, despite the widespread prescription of secondary preventive medications. There is scope to improve preventive measures after IS (in particular blood pressure) by incorporating evidence-based guidelines into quality assurance cycles in stroke care.
Source: BioMed Central - October 23, 2015 Category: Journals (General) Authors: Linda BrewerLisa MellonPatricia HallEamon DolanFrances HorganEmer ShelleyAnne HickeyDavid Williamson behalf of the ASPIRE-S Study Group Source Type: research

Development and psychometric evaluation of a new patient -reported outcome measure for stroke self -management: The Southampton Stroke Self - Management Questionnaire (SSSMQ)
Conclusions: Early findings suggest the Southampton Stroke Self-Management Questionnaire is a reliable and valid scale of self-management competency. The SSSMQ represents a potentially valid PROM for the evaluation of self-management following stroke.
Source: BioMed Central - October 3, 2015 Category: Journals (General) Authors: Emma J BogerMatthew HankinsSara H DemainSusan M Latter Source Type: research

Heterogeneity of aquaporin-4 localization and expression after focal cerebral ischemia underlies differences in white versus grey matter swelling
Conclusions: The findings reported here raise the possibility that cerebral white matter may play a heretofore underappreciated role in the formation of cerebral edema following ischemia.
Source: BioMed Central - September 30, 2015 Category: Journals (General) Authors: Jesse StokumRupal MehtaSvetlana IvanovaEdward YuVolodymyr GerzanichJ. Simard Source Type: research

Clinical usefulness and validity of robotic measures of reaching movement in hemiparetic stroke patients
Conclusions: The robot-derived measures could successfully differentiate between the paretic arm and the non-paretic arm and were valid in comparison to the well-established clinical scales.
Source: BioMed Central - August 11, 2015 Category: Journals (General) Authors: Eri OtakaYohei OtakaShoko KasugaAtsuko NishimotoKotaro YamazakiMichiyuki KawakamiJunichi UshibaMeigen Liu Source Type: research

A novel method for the quantification of key components of manual dexterity after stroke
Conclusions: Quantifying some of the key components of manual dexterity with the FFM is feasible in moderately affected hemiparetic patients. The FFM can detect group differences and individual profiles of deficient dexterity. The FFM is a promising tool for the measurement of key components of manual dexterity after stroke and could allow improved targeting of motor rehabilitation.
Source: BioMed Central - August 1, 2015 Category: Journals (General) Authors: Maxime TérémetzFlorence ColleSonia HamdounMarc MaierPåvel Lindberg Source Type: research

Clinical feasibility of interactive motion-controlled games for stroke rehabilitation
Conclusions: A post-stroke intervention using interactive motion-controlled games shows promise as a feasible and potentially effective treatment approach. This paper presents important recommendations for future game development and research to further explore long-term adherence, acceptability, safety and efficacy.Trial registrationAustralian and New Zealand Clinical Trials Registry (ACTRN12613000220763)
Source: BioMed Central - August 1, 2015 Category: Journals (General) Authors: Kelly BowerJulie LouieYoseph LandesrochaPaul SeedyAlexandra GorelikJulie Bernhardt Source Type: research

Predictors of caregiver depression and family functioning after perinatal stroke
Conclusions: Adverse parental outcomes can be predicted in perinatal stroke populations. Moreover, anxiety and stress management techniques, marital support, and psychoeducation regarding the unpreventable nature of perinatal stroke may be utilized in the future to enhance family outcomes.
Source: BioMed Central - July 14, 2015 Category: Journals (General) Authors: Taryn BemisterBrian BrooksRichard DyckAdam Kirton Source Type: research

Is there association between hyperdense middle cerebral artery sign on CT scan and time from stroke onset within the first 24-hours?
Conclusions: No evidence of a correlation between time of stroke onset and presence of a HAS within the first 24-h post acute ischaemic stroke was identified. The HAS was associated with a higher NIHSS score at presentation.
Source: BioMed Central - July 2, 2015 Category: Journals (General) Authors: James HaridyLeonid ChurilovPeter MitchellRichard DowlingBernard Yan Source Type: research