Never before has it been more exciting and important to be a neurologist

What are the current trends and hot topics in neurology? The increasing insights into the genetics and molecular bases of neurological disorders open new perspectives for specific and personalized treatments. This is evidenced most dramatically by the antisense therapy for spinal muscular atrophy. Promising neurological research currently targets neurodegenerative diseases such as amyotrophic lateral sclerosis, Parkinson’s disease, Duchenne muscular atrophy, or Huntington’s disease. Likewise, brain-machine interfaces and neuroprosthetics offer huge potential. Never before has it been more important and more exciting to be a neurologist! Neurological Research and Practice is celebrating its 1st anniversary of the submission system launch. As the Past President and one of the main drivers for the society’s own English-language open access journal, what has the journal achieved so far? Are you happy with the progress you are seeing now? Within only one year, a new journal has been established with a regular publication schedule of already 3 -4 articles per month with the first articles being published in February 2019. The article accesses of research articles, e.g., “Safety and clinical impact of FEES – results of the FEES registry”, or review articles, e.g., “Navigating choice in multiple sclerosis management”, demonstrate that the topics covered in the journal meet the readers’ interests. In addition to review and research...
Source: BioMed Central Blog - Category: General Medicine Authors: Tags: Uncategorized Source Type: blogs

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Publication date: February 2020Source: Learning and Individual Differences, Volume 78Author(s): Catherine Gunzenhauser, Henrik SaalbachAbstractSelf-regulation is crucial for acquiring mathematical competencies in elementary school. The present longitudinal study aimed at investigating determinants and consequences of domain-specific self-regulation with regard to the mathematics domain.Participants were N = 257 third graders (MAge = 8.59 years, SD = 0.57 years; 51% girls) from East Germany as well as children's mathematics teachers. The project included two time points (6-month interval). Children's self-re...
Source: Learning and Individual Differences - Category: Psychiatry & Psychology Source Type: research
Manchester City ’s fortunes changed dramatically with the takeover by Sheikh Mansour of Abu Dhabi. But after years of success, Europe’s governing body has banned the club from its most prestigious tournament, the Champions League. David Conn explains why. Plus: Alok Jha on the ethics of gene editingIt was deep into injury time in the final match of the 2011-12 season and Manchester City needed a goal to win the Premier League with just seconds remaining. The Argentinian striker Sergio Ag üero jinked past a QPR defender and smashed the ball into the net, sending the crowd into raptures and securing the club...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Manchester City Football UK news Gene editing Genetics Science Source Type: news
This article intends to verify the association of dysfunctional beliefs of personality disorders with the executive performance in people with juvenile myoclonic epilepsy (JME).MethodsFifty-two patients (35 women, 67.3%) with JME aged 18–50 yrs. (32.3 ± 9.7) were evaluated between May 2017 and April 2018 and compared with controls. All subjects were submitted to the Personality Beliefs Questionnaire (PBQ) (Beck &Beck, 1991; Savoia et al., 2006), Dysexecutive Questionnaire (DQ; Wilson et al., 1996; Macuglia et al., 2016), estimated intelligence quotient (IQ) using Vocabulary and Block Design tests, at...
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
FIBRE, fruit and vegetables cut the risk of a stroke but eggs may raise it, a major study suggests.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
A major study of more than 400,000 people suggested that consuming more milk, cheese and yogurt can cut the risk of the most common type of stroke.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Authors: Khan R Abstract Introduction: There has been considerable study assessing the treatment of cryptogenic stroke (CS) recently. This review examines the role of patent foramen ovale (PFO) closure in CS, while also discussing the evidence for alternative medical therapies in disease treatment.Areas Covered: PFO closure for treatment of CS has been assessed in 6 randomized controlled trials (RCTs). This review summarizes the background, results and limitations of these trials. Methodological and treatment-related differences in RCTs provide potential explanations for the discordance in outcomes observed between...
Source: Expert Review of Cardiovascular Therapy - Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research
Publication date: Available online 22 February 2020Source: Neuroscience LettersAuthor(s): Raffaele Nardone, Stefan Golaszewski, Aljoscha Thomschewski, Luca Sebastianelli, Viviana Versace, Francesco Brigo, Andrea Orioli, Leopold Saltuari, Yvonne Höller, Eugen TrinkaAbstractIn patients with amyotrophic lateral sclerosis (ALS) a motor cortical hyperexcitability has been reported in transcranial magnetic stimulation studies, but little is known about the neuronal excitability in other cortical areas. The aim of the present study was the functional evaluation of the sensory cortex in subjects with ALS by assessing the high...
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
Authors: Valentí V, Cienfuegos JA, Becerril Mañas S, Frühbeck G Abstract Bariatric-metabolic surgery is the safest, most effective and long-lasting treatment for obesity and its associated co-morbidities, whether they be metabolic (type 2 diabetes, hyperlipidemia non-alcoholic fatty liver disease) or cardiovascular (myocardial infarction, stroke). Due to the obesity pandemic, bariatric-metabolic surgery is the second most frequent intra-abdominal procedure and the gastroenterologist and the surgeon must be aware of the physiologic changes caused by the anatomic reconfiguration following surgery. ...
Source: Revista Espanola de Enfermedades Digestivas - Category: Gastroenterology Tags: Rev Esp Enferm Dig Source Type: research
CONCLUSION: The concentration of sdLDL in plasma lipoprotein spectrum obtained by two different laboratory procedures was analysed, compared, evaluated and 70% identical corresponding results have been confirmed. PMID: 32087095 [PubMed - as supplied by publisher]
Source: Neuroendocrinology Letters - Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research
CONCLUSIONS: This case indicates the need for early diagnosis and multidisciplinary action to achieve satisfactory quality of life in patients with 18q- syndrome. PMID: 32087092 [PubMed - as supplied by publisher]
Source: Neuroendocrinology Letters - Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research
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