Filtered By:
Source: Heart

This page shows you your search results in order of relevance. This is page number 7.

Order by Relevance | Date

Total 262 results found since Jan 2013.

Non-vitamin K antagonist oral anticoagulants (NOACs) for the management of venous thromboembolism
Learning objectives Understand the importance of venous thrombosis in cardiovascular medicine. Appreciate the mode of action of different oral anticoagulants. Recall the uses, risks and benefits of each non-vitamin K antagonist oral anticoagulants. Introduction Thrombosis is the common pathophysiology responsible for ischaemic heart disease, ischaemic stroke and venous thromboembolism (VTE), and a major contributor to the global disease burden.1 This effect is markedly more pronounced by considering the view that cancer is also a thrombotic disease.2 3 Cardiovascular disease (CVD, manifesting as acute coronary syndromes, m...
Source: Heart - June 5, 2016 Category: Cardiology Authors: Blann, A. D., Lip, G. Y. H. Tags: Education in Heart, Drugs: cardiovascular system, Acute coronary syndromes, Venous thromboembolism, Epidemiology Source Type: research

Cardiovascular highlights from non-cardiology journals
Pre-operative aspirin does not influence CABG outcomes Aspirin is a common therapy for risk reduction among patients with coronary artery disease. However, among patients undergoing coronary artery bypass surgery, the benefits of aspirin on the risk of myocardial infarction and stroke may be outweighed by perioperative bleeding risk. To address this question, the ATACAS trial randomized 2100 patients to either receive 100 mg aspirin daily or matching placebo for 4 days immediately prior to the operation with all patients resuming aspirin within 24 hours of their bypass surgery. The primary outcome was a composite of d...
Source: Heart - June 5, 2016 Category: Cardiology Authors: Bradley, S. M. Tags: Journal scan Source Type: research

Native valve disease in patients with non-valvular atrial fibrillation on warfarin or rivaroxaban
Conclusions We found that patients with AF and AS on oral anticoagulants may have distinctly different efficacy and safety outcomes than patients with MR or AR or no SVD. Trial registration number NCT00403767; Post-results.
Source: Heart - June 9, 2016 Category: Cardiology Authors: Breithardt, G., Baumgartner, H., Berkowitz, S. D., Hellkamp, A. S., Piccini, J. P., Lokhnygina, Y., Halperin, J. L., Singer, D. E., Hankey, G. J., Hacke, W., Becker, R. C., Nessel, C. C., Mahaffey, K. W., Califf, R. M., Fox, K. A. A., Patel, M. R., for th Tags: Open access, Drugs: cardiovascular system, Interventional cardiology, Aortic valve disease, Mitral valve disease Valvular heart disease Source Type: research

Cardiovascular disease risk assessment in HIV: navigating data-sparse zones
Persons with HIV are surviving longer than ever before due to effective antiretroviral therapy (ART) and are increasingly at risk for chronic, non-communicable diseases.1–3 Data from large cohorts in North America and Europe have demonstrated that HIV-infected persons have roughly 50% greater risks for myocardial infarction (MI) than uninfected persons, as well as greater risks for other cardiovascular diseases such as heart failure and stroke.4 5 These elevated risks for MI persist even after accounting for cardiovascular risk factors and ART regimens and are thought to result from HIV-associated inflammation, immun...
Source: Heart - July 10, 2016 Category: Cardiology Authors: Feinstein, M. J. Tags: Drugs: cardiovascular system, Acute coronary syndromes Editorials Source Type: research

Significance of apical cavity obliteration in apical hypertrophic cardiomyopathy
Conclusions The ratio of obliteration to cavity could provide useful information to predict the occurrence of adverse events in apical HCM.
Source: Heart - July 10, 2016 Category: Cardiology Authors: Kim, H., Park, J.-H., Won, K.-B., Yoon, H.-J., Park, H.-S., Cho, Y.-K., Nam, C.-W., Han, S., Hur, S.-H., Kim, Y.-N., Kim, K.-B. Tags: Hypertrophic cardiomyopathy, Drugs: cardiovascular system, Hypertension, Epidemiology Heart failure and cardiomyopathies Source Type: research

Perioperative outcomes of patients with hypertrophic cardiomyopathy undergoing non-cardiac surgery
Conclusions Patients with HCM undergoing high-risk and intermediate-risk non-cardiac surgeries have a low perioperative event rate, at an experienced centre. However, they have a higher risk of composite events versus matched patients without HCM.
Source: Heart - September 26, 2016 Category: Cardiology Authors: Dhillon, A., Khanna, A., Randhawa, M. S., Cywinski, J., Saager, L., Thamilarasan, M., Lever, H. M., Desai, M. Y. Tags: Hypertrophic cardiomyopathy, Drugs: cardiovascular system, Heart failure, Acute coronary syndromes, Clinical diagnostic tests, Epidemiology Heart failure and cardiomyopathies Source Type: research

Screening for atrial fibrillation in 13 122 Hong Kong citizens with smartphone electrocardiogram
Conclusion Community screening for AF with SL-ECG was feasible and it identified a significant proportion of citizens with newly diagnosed AF. The prevalence of AF in a Chinese population in Hong Kong was comparable with that of contemporary Western counterparts. Apart from age and sex, different anthropometric parameters and cardiovascular comorbid conditions were identified as independent predictors of AF.
Source: Heart - December 8, 2016 Category: Cardiology Authors: Chan, N.-y., Choy, C.-c. Tags: Editor's choice, Press releases, Drugs: cardiovascular system, Heart failure, Hypertension, Epidemiology, Metabolic disorders Arrhythmias and sudden death Source Type: research

Cochrane corner: self-monitoring and self-management of oral anticoagulation
Background Use of oral anticoagulants such as warfarin is increasing. Part of the reason for this is the rising prevalence of atrial fibrillation, an ageing population and the widening indications for treatment based on evidence of benefit in reducing risk of stroke. A meta-analysis of 29 randomised trials including 28 044 participants with atrial fibrillation found that warfarin decreased the absolute risk of stroke by 2.7% per year (the number needed to treat (NNT) 37) compared with placebo or no treatment and by 0.7% per year (NNT=143) compared with aspirin.1 Management of warfarin, however, is challenging bec...
Source: Heart - May 31, 2017 Category: Cardiology Authors: Heneghan, C. J., Spencer, E. A., Mahtani, K. R. Tags: Editorials Source Type: research

Association of physical activity trajectories with major cardiovascular diseases in elderly people
Conclusion Increasingly active trajectories of physical activity were associated with lower rates of cardiovascular diseases and overall mortality. Promoting at least 20 min/day of physical activity early in late life seems to provide the greatest cardiovascular benefits.
Source: Heart - February 16, 2022 Category: Cardiology Authors: Barbiellini Amidei, C., Trevisan, C., Dotto, M., Ferroni, E., Noale, M., Maggi, S., Corti, M. C., Baggio, G., Fedeli, U., Sergi, G. Tags: Editor's choice Cardiac risk factors and prevention Source Type: research

Smoking cessation, weight gain and risk of cardiovascular disease
Conclusions Postcessation weight gain did not attenuate the protective association between smoking cessation and risk of CVD.
Source: Heart - February 16, 2022 Category: Cardiology Authors: Wang, X., Dong, J.-Y., Cui, R., Muraki, I., Shirai, K., Yamagishi, K., Kokubo, Y., Saito, I., Yatsuya, H., Sawada, N., Iso, H., Tsugane, S., for the Japan Public Health Center-based Prospective Study Group Tags: Cardiac risk factors and prevention Source Type: research

Refined atrial fibrillation screening and cost-effectiveness in the German population
Conclusions In our middle-aged population cohort, we identified 0.2% new AF by single timepoint screening. There was a significant estimated risk of stroke and heart failure in these individuals. Cost-effectiveness for screening may be reached in individuals aged 65 years and older. The simple age cut-off is not improved by using Nt-proBNP as a biomarker to guide a screening programme.
Source: Heart - February 24, 2022 Category: Cardiology Authors: Schnabel, R. B., Wallenhorst, C., Engler, D., Blankenberg, S., Pfeiffer, N., Spruenker, N. A., Buettner, M., Michal, M., Lackner, K. J., Münzel, T., Wild, P. S., Martinez, C., Freedman, B., Gutenberg Health Study investigators Tags: Open access Cardiac risk factors and prevention Source Type: research

Management and outcomes of patients with left atrial appendage thrombus prior to percutaneous closure
Conclusion In the presence of LAA thrombus, IAT was the initial management strategy in half of our cohort, with initial thrombus resolution in 60% of these, but with a relatively high bleeding rate (~10%). Direct LAAC was feasible, with high procedural success and absence of periprocedural embolic complications. However, a high rate of device-related thrombosis was detected during follow-up.
Source: Heart - June 24, 2022 Category: Cardiology Authors: Marroquin, L., Tirado-Conte, G., Pracon, R., Streb, W., Gutierrez, H., Boccuzzi, G., Arzamendi-Aizpurua, D., Cruz-Gonzalez, I., Ruiz-Nodar, J. M., Kim, J.-S., Freixa, X., Lopez-Minguez, J. R., De Backer, O., Ruiz-Salmeron, R., Dominguez, A., McInerney, A. Tags: Open access Arrhythmias and sudden death Source Type: research

Eligibility for early rhythm control in patients with atrial fibrillation in the UK Biobank
Conclusion Around 80% of participants diagnosed with AF in the UK population are eligible for early rhythm-control. Early rhythm-control therapy was safe in routine care.
Source: Heart - November 10, 2022 Category: Cardiology Authors: Kany, S., Cardoso, V. R., Bravo, L., Williams, J. A., Schnabel, R., Fabritz, L., Gkoutos, G. V., Kirchhof, P. Tags: Open access Arrhythmias and sudden death Source Type: research

Cardiovascular disease and mortality sequelae of COVID-19 in the UK Biobank
Conclusions Individuals hospitalised with COVID-19 have increased risk of incident cardiovascular events across a range of disease and mortality outcomes. The risk of most events is highest in the early postinfection period. Individuals not requiring hospitalisation have increased risk of VTE, but not of other cardiovascular-specific outcomes.
Source: Heart - December 22, 2022 Category: Cardiology Authors: Raisi-Estabragh, Z., Cooper, J., Salih, A., Raman, B., Lee, A. M., Neubauer, S., Harvey, N. C., Petersen, S. E. Tags: Open access, Editor's choice, Press releases, COVID-19 Cardiac risk factors and prevention Source Type: research

Early surgical intervention versus conservative management of asymptomatic severe aortic stenosis: a systematic review and meta-analysis
Conclusions This study suggests that for patients with asymptomatic severe AS an early surgical intervention compared with a conservative WW strategy was associated with a lower heart failure hospitalisation and a similar rate of stroke or myocardial infarction, although with significant risk of bias. PROSPERO registration number CRD42021291144.
Source: Heart - January 27, 2023 Category: Cardiology Authors: Costa, G. N. F., Cardoso, J. F. L., Oliveiros, B., Goncalves, L., Teixeira, R. Tags: Valvular heart disease Source Type: research