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Source: Internal Medicine Journal

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Total 81 results found since Jan 2013.

Recurrent contrast ‐induced encephalopathy following coronary angiography
Contrast‐induced encephalopathy (CIE) is an acute and reversible neurological disturbance associated with the intra‐arterial administration of iodinated contrast medium during cardiac catheterisation. It may manifest with encephalopathy, motor and sensory disturbances; vision disturbances, including cortical blindness, ophthalmoplegia, aphasia; and seizures. Disruption of the blood–brain barrier and direct neuronal toxicity are believed to be implicated in the pathophysiology of the syndrome. Symptoms appear soon after contrast administration and resolve completely within 24–48 h. Risk factors may include hypertens...
Source: Internal Medicine Journal - February 14, 2017 Category: Internal Medicine Authors: Roberto Spina, Neil Simon, Romesh Markus, David W. M. Muller, Krishna Kathir Tags: Brief Communication Source Type: research

Disparities in the incidence of acute myocardial infarction: Long term trends from the Hunter Region
ConclusionsBetween 1996 and 2013 in the Hunter region, the adjusted incidence of AMI increased for regional patients compared to metropolitan patients with a trend towards a higher adjusted incidence of AMI in the indigenous population.
Source: Internal Medicine Journal - February 13, 2017 Category: Internal Medicine Authors: Allan J Davies, Crystal Naudin, Mohammed Al Omari, Arshad Khan, Chris Oldmeadow, Mark Jones, Bruce Bastian, Rohan Bhagwandeen, Peter Fletcher, James Leitch, Andrew Boyle Tags: Original Article Source Type: research

CHA2DS2VASc score predicts unsuccessful electrical cardioversion in patients with persistent atrial fibrillation
ConclusionThe CHA2DS2VAS score routinely used in thromboembolic risk assessment may be a simple, easy and reliable scoring system that can be used to predict unsuccessful electrical cardioversion.
Source: Internal Medicine Journal - November 8, 2016 Category: Internal Medicine Authors: Elzbieta Mlodawska, Anna Tomaszuk ‐Kazberuk, Paulina Lopatowska, Marcin Kaminski, Wlodzimierz Jerzy Musial Tags: Original Article Source Type: research

An audit of coagulation screening in patients presenting to the Emergency Department for potential stroke thrombolysis
ConclusionsA high proportion of laboratory specimens were unsuitable for testing and overall samples took an unacceptably long time to process. Point‐of‐care testing may potentially allow quicker decisions regarding whether thrombolysis is contra‐indicated but is likely to affect only a small proportion of patients.
Source: Internal Medicine Journal - October 31, 2016 Category: Internal Medicine Authors: Katie Thorne, Harry McNaughton, Mark Weatherall Tags: Original Article Source Type: research

Adoption of direct oral anticoagulants for stroke prevention in atrial fibrillation
Conclusion DOAC prescribing grew rapidly from 2013 to 2014, regionally and nationally. Warfarin prescriptions have remained stable, indicating that more patients are being appropriately anticoagulated for AF who previously were not. DOAC were found to be prescribed to patients with lower CHA2DS2VASc and HAS‐BLED scores, younger age and higher glomerular filtration rates. Aspirin therapy remains over utilised in AF.
Source: Internal Medicine Journal - July 11, 2016 Category: Internal Medicine Authors: D. Baker, B. Wilsmore, S. Narasimhan Tags: Original Article Source Type: research

Burden of Atrial Fibrillation: A Retrospective Review of Patients Presenting to Acute Medical Services
ConclusionAnti‐coagulation for stroke prevention in AF remains under‐utilised in eligible patients presenting to acute medical services at a tertiary level hospital.
Source: Internal Medicine Journal - June 30, 2016 Category: Internal Medicine Authors: Evan Jolliffe, Vivian Fu, Jeremiah Lanford, Mark Weatherall, Ian Rosemergy Tags: Original Article Source Type: research

Endovascular thrombectomy for acute ischaemic stroke – a real world experience
ConclusionsThis cohort of patients with anterior cerebral circulation occlusions were treated outside the well‐resourced situation of clinical trials and good functional outcomes are similar. The study translates endovascular thrombectomy to a “real world” situation.
Source: Internal Medicine Journal - June 26, 2016 Category: Internal Medicine Authors: Cecilia Cappelen‐Smith, Dennis Cordato, Zeljka Calic, Andrew Cheung, Jason Wenderoth Tags: Original Article Source Type: research

Outcomes are superior in patients with acute stroke from new zealand versus rest of world: data from the efficacy of nitric oxide in stroke (enos) trial
Source: Internal Medicine Journal - May 14, 2016 Category: Internal Medicine Tags: Abstracts Source Type: research

Anabolic androgenic steroids, an easily forgotten cause of polycythaemia and cerebral infarction
We report a case of exogenous anabolic androgenic steroid‐induced polycythaemia and stroke and explore possible pitfalls for clinicians.
Source: Internal Medicine Journal - April 6, 2016 Category: Internal Medicine Authors: M. S. Y. Low, S. Vilcassim, P. Fedele, G. Grigoriadis Tags: Brief Communication Source Type: research

The adoption of direct oral anticoagulants for stroke prevention in atrial fibrillation
ConclusionDOACs prescribing grew rapidly from 2013 to 2014, regionally and nationally. Warfarin prescriptions have remained stable, indicating that more patients are being appropriately anticoagulated for atrial fibrillation that previously were not. DOACs were found to be prescribed to patients with lower CHA2DS2VASc and HASBLED scores, younger age, and higher GFR. Aspirin therapy remains over utilised in AF.
Source: Internal Medicine Journal - April 3, 2016 Category: Internal Medicine Authors: David Baker, Bradley Wilsmore, Seshasayee Narasimhan Tags: Original Article Source Type: research

Quality of warfarin control in atrial fibrillation patients in South East Queensland, Australia
ConclusionsThe observed mean TTR of over 80% is superior to the minimum recommended threshold of 60%. The TTR achieved by the Queensland pathology practice demonstrates that dedicated warfarin programs can produce high quality warfarin care ensuring full benefit of warfarin for Australian patients.
Source: Internal Medicine Journal - April 3, 2016 Category: Internal Medicine Authors: Nijole Bernaitis, Tony Badrick, Andrew K Davey, Shailendra Anoopkumar‐Dukie Tags: Original Article Source Type: research

Do physicians correctly calculate thromboembolic risk scores? A comparison of concordance between manual and computer‐based calculation of CHADS2 and CHA2DS2‐VASc scores
CONCLUSIONWe have found a strong concordance between manual and computer‐based score calculation of both CHADS2 and CHA2DS2‐VASc risk scores with minimal changes in anticoagulation recommendations. The use of CHA2DS2‐VASc score significantly improves classification of atrial fibrillation patients at low and intermediate risk of stroke into higher grade of thromboembolic score. Moreover, CHA2DS2‐VASc score could identify ‘truly low risk” patients compared to CHADS2 score.
Source: Internal Medicine Journal - March 1, 2016 Category: Internal Medicine Authors: María Asunción Esteve‐Pastor, Francisco Marín, Vicente Bertomeu Martínez, Inmaculada Roldán Rabadán, Ángel Cequier Fillat, Lina Badimon, Javier Muñiz García, Mariano Valdés, Manuel Anguita Sánchez, Tags: Original Article Source Type: research

Cannabis, serotonergic drug use and stroke in a 50‐year‐old woman
Source: Internal Medicine Journal - December 9, 2015 Category: Internal Medicine Authors: W. Y. Yau, E. Chu, N. Lai Tags: Clinical‐scientific notes Source Type: research

Outcomes of Transcatheter Aortic Valve Implantation in High Surgical Risk and Inoperable Patients with Aortic Stenosis ‐ A Single Australian Centre Experience
ConclusionsTAVI with various valve systems, delivered via a number of approaches, is feasible in high surgical risk and inoperable patients with severe aortic stenosis, with acceptable outcomes at short‐ and intermediate‐term follow‐up.
Source: Internal Medicine Journal - October 1, 2015 Category: Internal Medicine Authors: Vijayakumar Subban, Dale Murdoch, Michael L Savage, James Crowhurst, Ramakrishna Saireddy, Karl K Poon, Alexander Incani, Nicholas Bett, Darryl J Burstow, Gregory M Scalia, Andrew Clarke, Owen Christopher Raffel, Constantine N Aroney, Darren L Walters Tags: Original Article Source Type: research

Atrial fibrillation in older inpatients: are there any differences in clinical characteristics and pharmacological treatment between the frail and the non‐frail?
ConclusionsFrailty status had little impact on antithrombotic prescription and no impact on anti‐arrhythmic prescription.
Source: Internal Medicine Journal - September 19, 2015 Category: Internal Medicine Authors: T. N. Nguyen, R. G. Cumming, S. N. Hilmer Tags: Original Article Source Type: research