Filtered By:
Specialty: Internal Medicine
Source: PLoS Medicine
This page shows you your search results in order of relevance. This is page number 2.
Order by Relevance | Date
Total 74 results found since Jan 2013.
Uncovering Treatment Burden as a Key Concept for Stroke Care: A Systematic Review of Qualitative Research
Conclusions Stroke management is extremely demanding for patients, and treatment burden is influenced by micro and macro organisation of health services. Knowledge deficits mean patients are ill equipped to organise their care and develop coping strategies, making adherence less likely. There is a need to transform the approach to care provision so that services are configured to prioritise patient needs rather than those of health care systems. Systematic Review Registration International Prospective Register of Systematic Reviews CRD42011001123Please see later in the article for the Editors' Summary
Source: PLoS Medicine - June 25, 2013 Category: Internal Medicine Authors: Katie Gallacher et al. Source Type: research
The Effect of Tobacco Control Measures during a Period of Rising Cardiovascular Disease Risk in India: A Mathematical Model of Myocardial Infarction and Stroke
Conclusions Smoke-free laws and substantially increased tobacco taxation appear to be markedly potent population measures to avert future cardiovascular deaths in India. Despite the rise in co-morbid cardiovascular disease risk factors like hyperlipidemia and hypertension in low- and middle-income countries, tobacco control is likely to remain a highly effective strategy to reduce cardiovascular deaths.Please see later in the article for the Editors' Summary
Source: PLoS Medicine - July 9, 2013 Category: Internal Medicine Authors: Sanjay Basu et al. Source Type: research
Long-term trends in incidence and risk factors for ischaemic stroke subtypes: Prospective population study of the South London Stroke Register
by Hatem A. Wafa, Charles D. A. Wolfe, Anthony Rudd, Yanzhong Wang
BackgroundAs the average life expectancy increases, more people are predicted to have strokes. Recent studies have shown an increasing incidence in certain types of cerebral infarction. We aimed to estimate time trends in incidence, prior risk factors, and use of preventive treatments for ischaemic stroke (IS) aetiological subtypes and to ascertain any demographic disparities. Methods and findingsPopulation-based data from the South London Stroke Register (SLSR) between 2000 and 2015 were studied. IS was classified, based on the underlying mechanism, into l...
Source: PLoS Medicine - October 5, 2018 Category: Internal Medicine Authors: Hatem A. Wafa Source Type: research
Long-term trends in death and dependence after ischaemic strokes: A retrospective cohort study using the South London Stroke Register (SLSR)
This study estimates time trends in mortality and functional dependence by ischaemic stroke (IS) aetiological subtype over a 16-year period. Methods and findingsThe study population was 357,308 in 2011; 50.4% were males, 56% were white, and 25% were of black ethnic backgrounds. Population-based case ascertainment of stroke was conducted, and all participants who had their first-ever IS between 2000 and 2015 were identified. Further classification was concluded according to the underlying mechanism into large-artery atherosclerosis (LAA), cardio-embolism (CE), small-vessel occlusion (SVO), other determined aetiologies (OTH)...
Source: PLoS Medicine - March 11, 2020 Category: Internal Medicine Authors: Hatem A. Wafa Source Type: research
Effectiveness of a primary care-based integrated mobile health intervention for stroke management in rural China (SINEMA): A cluster-randomized controlled trial
This study aims to determine whether a primary care-based integrated mobile health intervention (SINEMA intervention) could improve stroke management in rural China. Methods and findingsBased on extensive barrier analyses, contextual research, and feasibility studies, we conducted a community-based, two-arm cluster-randomized controlled trial with blinded outcome assessment in Hebei Province, rural Northern China including 1,299 stroke patients (mean age: 65.7 [SD:8.2], 42.6% females, 71.2% received education below primary school) recruited from 50 villages between June 23 and July 21, 2017. Villages were randomly assigned...
Source: PLoS Medicine - April 28, 2021 Category: Internal Medicine Authors: Lijing L. Yan Source Type: research
Evaluation of a multicomponent intervention to shorten thrombolytic door-to-needle time in stroke patients in China (MISSION): A cluster-randomized controlled trial
ConclusionsThe teleconference-delivered PEITEM intervention resulted in a moderate but clinically relevant shorter DNT and better functional outcome in AIS patients receiving IVT. Trial registrationClinicaltrials.gov NCT03317639.
Source: PLoS Medicine - July 5, 2022 Category: Internal Medicine Authors: Wansi Zhong Source Type: research
Estimated stroke risk, yield, and number needed to screen for atrial fibrillation detected through single time screening: a multicountry patient-level meta-analysis of 141,220 screened individuals
by Nicole Lowres, Jake Olivier, Tze-Fan Chao, Shih-Ann Chen, Yi Chen, Axel Diederichsen, David A. Fitzmaurice, Juan Jose Gomez-Doblas, Joseph Harbison, Jeff S. Healey, F. D. Richard Hobbs, Femke Kaasenbrood, William Keen, Vivian W. Lee, Jes S. Lindholt, Gregory Y. H. Lip, Georges H. Mairesse, Jonathan Mant, Julie W. Martin, Enrique Mart ín-Rioboó, David D. McManus, Javier Muñiz, Thomas Münzel, Juliet Nakamya, Lis Neubeck, Jessica J. Orchard, Luis Ángel Pérula de Torres, Marco Proietti, F. Russell Quinn, Andrea K. Roalfe, Roopinder K. Sandhu, Renate B. Schnabel, Breda Smyth, Apurv Soni, Robert Tieleman, Jiguang Wang, ...
Source: PLoS Medicine - September 24, 2019 Category: Internal Medicine Authors: Nicole Lowres Source Type: research
Association between exercise habits and stroke, heart failure, and mortality in Korean patients with incident atrial fibrillation: A nationwide population-based cohort study
by Hyo-Jeong Ahn, So-Ryoung Lee, Eue-Keun Choi, Kyung-Do Han, Jin-Hyung Jung, Jae-Hyun Lim, Jun-Pil Yun, Soonil Kwon, Seil Oh, Gregory Y. H. Lip
BackgroundThere is a paucity of information about cardiovascular outcomes related to exercise habit change after a new diagnosis of atrial fibrillation (AF). We investigated the association between exercise habits after a new AF diagnosis and ischemic stroke, heart failure (HF), and all-cause death. Methods and findingsThis is a nationwide population-based cohort study using data from the Korea National Health Insurance Service. A retrospective analysis was performed for 66,692 pa...
Source: PLoS Medicine - June 8, 2021 Category: Internal Medicine Authors: Hyo-Jeong Ahn Source Type: research
Acute Cardiovascular Events after Herpes Zoster: A Self-Controlled Case Series Analysis in Vaccinated and Unvaccinated Older Residents of the United States
Conclusions Stroke and MI rates are transiently increased after exposure to herpes zoster. We found no evidence for a role of zoster vaccination in these associations. These findings enhance our understanding of the temporality and magnitude of the association between zoster and acute cardiovascular events.
Source: PLoS Medicine - December 15, 2015 Category: Internal Medicine Authors: Caroline Minassian et al. Source Type: research
Mortality attributable to hot and cold ambient temperatures in India: a nationally representative case-crossover study
ConclusionsPublic health interventions to mitigate temperature effects need to focus not only on extremely hot temperatures but also moderately cold temperatures. Future absolute totals of temperature-related deaths are likely to depend on the large absolute numbers of people exposed to both extremely hot and moderately cold temperatures. Similar large-scale and nationally representative studies are required in other low- and middle-income countries to better understand the impact of future temperature changes on cause-specific mortality.
Source: PLoS Medicine - July 24, 2018 Category: Internal Medicine Authors: Sze Hang Fu Source Type: research
The Association between Sulfonylurea Use and All-Cause and Cardiovascular Mortality: A Meta-Analysis with Trial Sequential Analysis of Randomized Clinical Trials
Conclusions Sulfonylureas are not associated with increased risk for all-cause mortality, cardiovascular mortality, myocardial infarction, or stroke. Current evidence supports the safety of sulfonylureas; an absolute risk of 0.5% could be firmly discarded. Review registration PROSPERO CRD42014004330
Source: PLoS Medicine - April 11, 2016 Category: Internal Medicine Authors: Dimitris Varvaki Rados Source Type: research
Incidence of eclampsia and related complications across 10 low- and middle-resource geographical regions: Secondary analysis of a cluster randomised controlled trial
ConclusionsThe large variation in eclampsia and maternal and neonatal fatality from hypertensive disorders of pregnancy between countries emphasises that inequality and inequity persist in healthcare for women with hypertensive disorders of pregnancy. Alongside the growing interest in improving community detection and health education for these disorders, efforts to improve quality of care within healthcare facilities are key. Strategies to prevent eclampsia should be informed by local data. Trial registrationISRCTN: 41244132.
Source: PLoS Medicine - March 28, 2019 Category: Internal Medicine Authors: Nicola Vousden Source Type: research
Incidence of nonvalvular atrial fibrillation and oral anticoagulant prescribing in England, 2009 to 2019: A cohort study
ConclusionsThe incidence of NVAF increased between 2009 and 2015, before plateauing. Underprescribing of OACs in NVAF is associated with a range of comorbidities, ethnicity, and socioeconomic factors, demonstrating the need for initiatives to reduce inequalities in the care for AF patients.
Source: PLoS Medicine - June 7, 2022 Category: Internal Medicine Authors: Alyaa M. Ajabnoor Source Type: research
The Causal Effect of Vitamin D Binding Protein (DBP) Levels on Calcemic and Cardiometabolic Diseases: A Mendelian Randomization Study
Conclusions DBP has no demonstrable causal effect on any of the diseases or traits investigated here, except 25OHD levels. It remains to be determined whether 25OHD has a causal effect on these outcomes independent of DBP.Please see later in the article for the Editors' Summary
Source: PLoS Medicine - October 28, 2014 Category: Internal Medicine Authors: Aaron Leong et al. Source Type: research
