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Specialty: Internal Medicine
Source: Annals of Medicine
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Total 216 results found since Jan 2013.
Obstructive sleep apnea risk and psychological health among non-Hispanic blacks in the Metabolic Syndrome Outcome (MetSO) cohort study.
CONCLUSION: Our results suggest that non-Hispanic blacks with metabolic syndrome who experience anxiety and/or depression should be screened for OSA.
PMID: 26593384 [PubMed - indexed for MEDLINE]
Source: Annals of Medicine - October 14, 2016 Category: Internal Medicine Tags: Ann Med Source Type: research
Time interval between infective endocarditis first symptoms and diagnosis: relationship to infective endocarditis characteristics, microorganisms and prognosis.
CONCLUSIONS: The time interval between IE first symptoms and diagnosis is closely related to the IE clinical presentation, patient characteristics and causative microorganism. Better prognosis reported in late-diagnosed IE may be related to a higher rate of valvular surgery. KEY MESSAGES Infective endocarditis, which time interval between first symptoms and diagnosis was less than one month, were mainly due to Staphylococcus aureus in France. Staphylococcus aureus infective endocarditis were associated with septic shock, transient ischemic attack or stroke and higher mortality rates than infective endocarditis due to other...
Source: Annals of Medicine - November 5, 2016 Category: Internal Medicine Tags: Ann Med Source Type: research
Diabetes and new-onset atrial fibrillation in a hypertensive population.
CONCLUSION: Diabetes was modestly associated with new-onset AF in hypertensive patients with no ischemic vascular disease. Among diabetic patients, only obesity reached significance in its association with this arrhythmia.
PMID: 26939743 [PubMed - indexed for MEDLINE]
Source: Annals of Medicine - January 1, 2017 Category: Internal Medicine Tags: Ann Med Source Type: research
Effect of renal function on whole blood and fibrin clot formation in atrial fibrillation patients on warfarin.
CONCLUSION: In warfarinised AF patients, renal function is linked to whole blood clot and fibrin clot formation, structure and dissolution, but has no effect on the INR. Key messages Despite oral anticoagulation, patients with atrial fibrillation (AF) still suffer from stroke and venous thromboembolism. The effect of renal function in warfarinised patients with AF is unknown and may account for excess thrombosis and/or haemorrhage. Using two different laboratory methods, our data point to an effect of renal function on clot structure and function that is independent of an effect of warfarin.
PMID: 27043881 [PubMed - indexed for MEDLINE]
Source: Annals of Medicine - January 20, 2017 Category: Internal Medicine Tags: Ann Med Source Type: research
Is monocyte to HDL ratio superior to monocyte count in predicting the cardiovascular outcomes: evidence from a large cohort of Chinese patients undergoing coronary angiography.
CONCLUSIONS: Our data firstly indicated that MHR was an independent predictor of MACEs whereas the prognostic impact was not superior to MC in patients who underwent coronary angiography. Key Messages MHR has been suggested as a novel prognostic indicator of several cardiovascular diseases. No study is currently available regarding the comparison of MHR to MC in predicting the outcomes in a large cohort of patients undergoing coronary angiography. Our data firstly indicate that MHR is independently associated with MACEs in patients undergoing coronary angiography whereas the prognostic impact is similar to MC.
PMID: 27...
Source: Annals of Medicine - July 8, 2017 Category: Internal Medicine Tags: Ann Med Source Type: research
Role of lipids and intraplaque hypoxia in the formation of neovascularization in atherosclerosis.
Authors: Chistiakov DA, Melnichenko AA, Myasoedova VA, Grechko AV, Orekhov AN
Abstract
According to the current paradigm, chronic vascular inflammation plays a central role in the pathogenesis of atherosclerosis. The plaque progression is typically completed with rupture and subsequent acute cardiovascular complications. Previously, the role of adventitial vasa vasorum in atherogenesis was underestimated. However, investigators then revealed that vasa vasorum neovascularization can be observed when no clinical manifestation of atherosclerosis is present. Vasa vasorum is involved in various proatherogenic processes ...
Source: Annals of Medicine - August 13, 2017 Category: Internal Medicine Tags: Ann Med Source Type: research
Direct, indirect and total bilirubin and risk of incident coronary heart disease in the Dongfeng-Tongji cohort.
CONCLUSION: DBIL was associated with a dose-response increased risk for CHD incidence. However, a U-shaped association existed between TBIL, IBIL and incident CHD risk.
PMID: 28879775 [PubMed - as supplied by publisher]
Source: Annals of Medicine - September 9, 2017 Category: Internal Medicine Tags: Ann Med Source Type: research
Enhancing the 'real world' prediction of cardiovascular events and major bleeding with the CHA2DS2-VASc and HAS-BLED scores using multiple biomarkers.
CONCLUSIONS: Addition of biomarkers enhanced the predictive value of CHA2DS2-VASc and HAS-BLED, although the overall improvement was modest and the added predictive advantage over original scores was marginal.
PMID: 28892413 [PubMed - as supplied by publisher]
Source: Annals of Medicine - September 13, 2017 Category: Internal Medicine Tags: Ann Med Source Type: research
Next Generation Sequencing Applications for Cardiovascular Disease.
Authors: Kalayinia S, Goodarzynejad H, Maleki M, Mahdieh N
Abstract
The Human Genome Project (HGP), as the primary sequencing of the human genome, lasted more than one decade to be completed using the traditional Sanger's method. At present, next-generation sequencing (NGS) technology could provide the genome sequence data in hours. NGS has also decreased the expense of sequencing; therefore, nowadays it is possible to carry out both whole-genome (WGS) and whole-exome sequencing (WES) for the variations detection in patients with rare genetic diseases as well as complex disorders such as common cardiovascular disea...
Source: Annals of Medicine - October 16, 2017 Category: Internal Medicine Tags: Ann Med Source Type: research
The association of non-alcoholic fatty liver disease and atrial fibrillation: a review.
Authors: Juhani Käräjämäki A, Hukkanen J, Ukkola O
Abstract
Non-alcoholic fatty liver disease (NAFLD) is highly prevalent and causes an enormous burden to human health and health-care systems all over the world. A great proportion of this burden results from increased risk of cardiovascular diseases. Atrial fibrillation (AF) is the most common chronic heart arrhythmia globally and it increases the risk of embolic stroke and heart failure. Recent studies have explored the association between NAFLD and AF with somewhat conflicting results. However, ultrasound-verified prospective studies concur that NAFLD is asso...
Source: Annals of Medicine - June 26, 2018 Category: Internal Medicine Tags: Ann Med Source Type: research
Left atrial thrombus resolution in non-valvular atrial fibrillation or flutter: Biomarker substudy results from a prospective study with rivaroxaban (X-TRA).
CONCLUSIONS: Biomarkers of inflammation are significantly associated with LA/LAA thrombus outcomes in AF patients prospectively treated with rivaroxaban.
PMID: 29956554 [PubMed - as supplied by publisher]
Source: Annals of Medicine - July 1, 2018 Category: Internal Medicine Tags: Ann Med Source Type: research
Thoracic endovascular aortic repair versus open chest surgical repair for patients with type B aortic dissection: A systematic review and meta-analysis.
Conclusions: The findings of this meta-analysis study suggested that TEVAR resulted in more short-term survival benefits. Moreover, the reduced risk of acute renal failure, respiratory failure and bleeding was detected in TEVAR group. The treatment effects of TEVAR versus OCSR on specific complications should be further verified by a study with high-level of evidence. Key message Comprehensive collected studies investigated the treatment effectiveness between TEVAR and OCSR for TBAD patients TEVAR resulted in more survival benefits, in addition to lower risk of acute renal failure, respiratory failure and bleeding The resu...
Source: Annals of Medicine - October 12, 2019 Category: Internal Medicine Tags: Ann Med Source Type: research
Endothelial function in patients with atrial fibrillation.
Authors: Khan AA, Thomas GN, Lip GYH, Shantsila A
Abstract
Atrial fibrillation is the most common heart arrhythmia and is associated with poor outcomes. The adverse effects of atrial fibrillation are mediated through multiple pathways, including endothelial dysfunction, as measured by flow-mediated dilatation. Flow-mediated dilatation has demonstrated endothelial dysfunction in several conditions and is associated with poor outcomes including mortality, yet can be improved with medical therapy. It is thus a useful tool in assessing endothelial function in patients.Endothelial dysfunction is present in patients with...
Source: Annals of Medicine - January 8, 2020 Category: Internal Medicine Tags: Ann Med Source Type: research
Prognostic value of myocardial injury-related findings onresting electrocardiography for cardiovascular risk in the asymptomatic general population: The 12-year follow-up report from the Ansan-Ansung cohort.
Conclusions: The presence of STA oranterior PQ wasassociated with worse cardiovascular outcomes in the asymptomatic general population. However, the addition of MIFs to the conventional risk estimators was of limited value in the prediction of MACEs. Key MessagesMyocardial injury-related findings including ST-T wave abnormalities and anterior pathologic Q waves in resting electrocardiography predict long-term cardiovascular outcomes in an asymptomatic low-risk population.However, ST-T wave abnormalities and anterior pathologic Q waves add only limited value to conventional cardiovascular risk estimators in the prediction o...
Source: Annals of Medicine - April 28, 2020 Category: Internal Medicine Tags: Ann Med Source Type: research
Title: Cytomegalovirus antibody levels and mortality among hospitalized elderly patients.
Conclusions: Increased IgG antibody levels against CMV are associated with increased short and long-term mortality in elderly hospitalized patients, especially in the patients without cardiovascular disease.
PMID: 32803995 [PubMed - as supplied by publisher]
Source: Annals of Medicine - August 19, 2020 Category: Internal Medicine Tags: Ann Med Source Type: research
