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Source: Respiratory Care
Infectious Disease: Influenza

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Total 211 results found since Jan 2013.

Healthcare personnel in 2016-2019 prospective cohort infrequently got vaccinated, worked while ill, and frequently used antibiotics rather than antivirals against viral influenza illnesses
Influenza Other Respir Viruses. 2023 Sep 7;17(9):e13189. doi: 10.1111/irv.13189. eCollection 2023 Sep.ABSTRACTBACKGROUND: Uncertainty about risk of illness and the value of influenza vaccines negatively affects vaccine uptake among persons targeted for influenza vaccination.METHODS: During 2016-2019, we followed a cohort of healthcare personnel (HCP) targeted for free-of-charge influenza vaccination in five Lima hospitals to quantify risk of influenza, workplace presenteeism (coming to work despite illness), and absenteeism (taking time off from work because of illness). The HCP who developed acute respiratory illnesses (A...
Source: Respiratory Care - September 11, 2023 Category: Respiratory Medicine Authors: Eduardo Azziz-Baumgartner Joan Neyra Tat S Yau Giselle Soto Daniel Owusu Chao Zhang Candice Romero Young M Yoo Miriam Gonzales Yeny Tinoco Mar ía Silva Eduar Bravo Nancy Rojas Serrano Eduardo Matos Victor Chavez-Perez Juan Carlos Castro Maria Esther Cast Source Type: research

Cost and health-related quality of life for children hospitalized with respiratory syncytial virus in Central China
CONCLUSIONS: RSV-associated hospitalization poses high economic and health burden in Central China particularly for children <1 year old. Our findings are crucial for determining the priority of interventions and allocation of health resources.PMID:37640557 | DOI:10.1111/irv.13180
Source: Respiratory Care - August 28, 2023 Category: Respiratory Medicine Authors: Lingshuang Ren Lidan Cui Qianli Wang Liujiong Gao Meng Xu Meng Wang Qianhui Wu Jinxin Guo Li Lin Yuxia Liang Nuolan Liu Yibing Cheng Juan Yang Hongjie Yu Source Type: research

Age-specific severity of severe acute respiratory syndrome coronavirus 2  in February 2020 to June 2021 in the Netherlands
CONCLUSION: Whereas the increase in severity of Severe Acute Respiratory Syndrome Coronavirus 2 with age remained stable, the risk of death upon infection decreased over time. A significant drop in risk of death among elderly coincided with the introduction of COVID-19 vaccination.PMID:37621921 | PMC:PMC10444602 | DOI:10.1111/irv.13174
Source: Respiratory Care - August 25, 2023 Category: Respiratory Medicine Authors: Pieter T de Boer Jan van de Kassteele Eric R A Vos Liselotte van Asten Dave A Dongelmans Arianne B van Gageldonk-Lafeber Gerco den Hartog Agnetha Hofhuis Fiona van der Klis Dylan W de Lange Lenny Stoeldraijer RIVM COVID ‐19 epidemiology and surveillance Source Type: research

Estimating SARS-CoV-2 infections and associated changes in COVID-19 severity and fatality
CONCLUSIONS: Since 2021, changes in the dominant SARS-CoV-2 variant, vaccination rollout, and the shift of infection to younger ages have reduced SARS-CoV-2 infection ascertainment. The same factors, combined with the improvement of patient management and care, contributed to a massive reduction in the severity and fatality of COVID-19.PMID:37599801 | PMC:PMC10432583 | DOI:10.1111/irv.13181
Source: Respiratory Care - August 21, 2023 Category: Respiratory Medicine Authors: Valentina Marziano Giorgio Guzzetta Francesco Menegale Chiara Sacco Daniele Petrone Alberto Mateo Urdiales Martina Del Manso Antonino Bella Massimo Fabiani Maria Fenicia Vescio Flavia Riccardo Piero Poletti Mattia Manica Agnese Zardini Valeria d'Andrea Fi Source Type: research

Comparison of clinical outcomes, demographic, and laboratory characteristics of hospitalized COVID-19 patients during major three waves driven by Alpha, Delta, and Omicron variants in Tehran, Iran
CONCLUSIONS: Although the Omicron variant caused less severe disease, in older patients who were hospitalized due to Omicron infection, longer hospital and ICU stays were reported, which could be attributed to their old age. In particular, elderly patients are more vulnerable to severe COVID-19; otherwise, as expected, other laboratory parameters and clinical outcomes were in accordance with differences in pathogenicity and infectivity of these variants.PMID:37565071 | PMC:PMC10410233 | DOI:10.1111/irv.13184
Source: Respiratory Care - August 11, 2023 Category: Respiratory Medicine Authors: Zahra Heydarifard Nazanin-Zahra Shafiei-Jandaghi Moslem Safaei Forough Tavakoli Somayeh Shatizadeh Malekshahi Source Type: research

Safety and efficacy of AK0529 in respiratory syncytial virus-infected infant patients: A phase 2 proof-of-concept trial
CONCLUSIONS: AK0529 was well tolerated in hospitalized RSV-infected infant patients. Treatment with AK0529 2 mg/kg bid was observed to reduce viral load and Wang Respiratory Score.CLINICAL TRIALS REGISTRATION: NCT02654171.PMID:37502622 | PMC:PMC10368966 | DOI:10.1111/irv.13176
Source: Respiratory Care - July 28, 2023 Category: Respiratory Medicine Authors: Li-Min Huang Andreas Schibler Yi-Chuan Huang Andrew Tai Hsin Chi Chae-Hee Chieng Jinn-Li Wang Aviv Goldbart Swee-Ping Tang Yhu-Chering Huang Shane George Derya Alabaz Lea Bentur Siew-Choo Su Jessie de Bruyne Bulent Karadag Feng Gu Gang Zou Stephen Toovey Source Type: research

Severe forms of influenza infections admitted in intensive care units: Analysis of mortality factors
CONCLUSION: Patient's underlying conditions influence hospital admission and secondary ICU admission but were not found to impact ICU mortality except in patients age >65, history of cancer, and bacterial coinfections. Pulmonary involvement was often present, required MV, and often evolved toward ARDS. ICU mortality was strongly related to ARDS severity. We recommend rapid ICU admission of patients with influenza-related pneumonia, management of bacterial coinfection, and early administration of oseltamivir.PMID:37483265 | PMC:PMC10359970 | DOI:10.1111/irv.13168
Source: Respiratory Care - July 24, 2023 Category: Respiratory Medicine Authors: Victor Verdier Fran çois Lilienthal Arnaud Desvergez Virgile Gazaille Arnaud Winer Fabrice Paganin Source Type: research

Understanding the Global Burden of Influenza in Adults Aged 18-64  years: A Systematic Literature Review from 2012 to 2022
CONCLUSIONS: High levels of hospitalization and outpatient visits demonstrated a clinical influenza-associated burden on patients and healthcare systems, which is exacerbated by comorbidities. Considering the size and breadth of the general population aged 18-64 years, the limited humanistic and economic findings of this SLR likely reflect an underreported burden. Greater investigation into indirect costs and prolonged absenteeism associated with influenza infection is required to fully understand the economic burden in this population.PMID:37470942 | DOI:10.1007/s12325-023-02610-1
Source: Respiratory Care - July 20, 2023 Category: Respiratory Medicine Authors: Farzaneh Maleki Verna Welch Santiago M C Lopez Alejandro Cane Jakob Langer Ashley Enstone Kristen Markus Olivia Wright Nicole Hewitt Isabelle Whittle Source Type: research