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Source: Reviews in Cardiovascular Medicine
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Total 968 results found since Jan 2013.
Simulation of anticoagulation in atrial fibrillation patients with rivaroxaban-from trial to target population
This study aimed to estimate the real-world outcomes of rivaroxaban in patients with AF accurately. A discrete event simulation (DES) was used to predict the counterfactual results of the ROCKET AF study. The hypothetical cohorts of patients were generated using Monte Carlo simulation according to the baseline covariate distributions that matched the marginal distribution of covariates reported in the ROCKET AF and three observational studies. The DES model structure was constructed based on a priori knowledge about disease progression and possible outcomes of patients with AF. The DES model accurately replicated the overa...
Source: Reviews in Cardiovascular Medicine - September 26, 2021 Category: Cardiology Authors: Chi Zhang Wei-Wei Wang Mang-Mang Pan Zhi-Chun Gu Source Type: research
Bleeding risk in patients with atrial fibrillation treated with combined anti-platelet and non-vitamin K antagonist oral anticoagulant therapy
CONCLUSIONS: The combination therapy group had higher incidences of any bleeding events compared to the monotherapy in patients with appropriate dosing. However, there was no difference in stroke/SE, and MACE. The bleeding risk in AF patients taking the combination of NOACs and APT should be carefully evaluated.PMID:35092194 | DOI:10.31083/j.rcm2301002
Source: Reviews in Cardiovascular Medicine - January 29, 2022 Category: Cardiology Authors: Dong Geum Shin Sunhwa Kim Yoo Ri Kim Source Type: research
