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Specialty: Neurology
Source: Journal of Clinical Neurology
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Total 608 results found since Jan 2013.

Relationship Between MicroRNA Signature and Arterial Stiffness in Patients With Ischemic Stroke
CONCLUSIONS: The expression level of let-7i was independently related to arterial stiffness in patients with cerebral infarction, suggesting that it plays a pathophysiological role in atherosclerosis.PMID:36606643 | DOI:10.3988/jcn.2023.19.1.28
Source: Journal of Clinical Neurology - January 6, 2023 Category: Neurology Authors: Sang-Jin Lee Jeong-Min Kim Eun Sun Lee Kwang-Yeol Park Hye Ryoun Kim Source Type: research

Update on the Epidemiology, Pathogenesis, and Biomarkers of Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy
J Clin Neurol. 2023 Jan;19(1):12-27. doi: 10.3988/jcn.2023.19.1.12.ABSTRACTCerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic disorder of the cerebral small blood vessels. It is caused by mutations in the NOTCH3 gene on chromosome 19, and more than 280 distinct pathogenic mutations have been reported to date. CADASIL was once considered a very rare disease with an estimated prevalence of 1.3-4.1 per 100,000 adults. However, recent large-scale genomic studies have revealed a high prevalence of pathogenic NOTCH3 variants among the general populati...
Source: Journal of Clinical Neurology - January 6, 2023 Category: Neurology Authors: Yumi Yamamoto Yi-Chu Liao Yi-Chung Lee Masafumi Ihara Jay Chol Choi Source Type: research

Relationship Between MicroRNA Signature and Arterial Stiffness in Patients With Ischemic Stroke
CONCLUSIONS: The expression level of let-7i was independently related to arterial stiffness in patients with cerebral infarction, suggesting that it plays a pathophysiological role in atherosclerosis.PMID:36606643 | DOI:10.3988/jcn.2023.19.1.28
Source: Journal of Clinical Neurology - January 6, 2023 Category: Neurology Authors: Sang-Jin Lee Jeong-Min Kim Eun Sun Lee Kwang-Yeol Park Hye Ryoun Kim Source Type: research

Update on the Epidemiology, Pathogenesis, and Biomarkers of Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy
J Clin Neurol. 2023 Jan;19(1):12-27. doi: 10.3988/jcn.2023.19.1.12.ABSTRACTCerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic disorder of the cerebral small blood vessels. It is caused by mutations in the NOTCH3 gene on chromosome 19, and more than 280 distinct pathogenic mutations have been reported to date. CADASIL was once considered a very rare disease with an estimated prevalence of 1.3-4.1 per 100,000 adults. However, recent large-scale genomic studies have revealed a high prevalence of pathogenic NOTCH3 variants among the general populati...
Source: Journal of Clinical Neurology - January 6, 2023 Category: Neurology Authors: Yumi Yamamoto Yi-Chu Liao Yi-Chung Lee Masafumi Ihara Jay Chol Choi Source Type: research

Relationship Between MicroRNA Signature and Arterial Stiffness in Patients With Ischemic Stroke
CONCLUSIONS: The expression level of let-7i was independently related to arterial stiffness in patients with cerebral infarction, suggesting that it plays a pathophysiological role in atherosclerosis.PMID:36606643 | DOI:10.3988/jcn.2023.19.1.28
Source: Journal of Clinical Neurology - January 6, 2023 Category: Neurology Authors: Sang-Jin Lee Jeong-Min Kim Eun Sun Lee Kwang-Yeol Park Hye Ryoun Kim Source Type: research

Update on the Epidemiology, Pathogenesis, and Biomarkers of Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy
J Clin Neurol. 2023 Jan;19(1):12-27. doi: 10.3988/jcn.2023.19.1.12.ABSTRACTCerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic disorder of the cerebral small blood vessels. It is caused by mutations in the NOTCH3 gene on chromosome 19, and more than 280 distinct pathogenic mutations have been reported to date. CADASIL was once considered a very rare disease with an estimated prevalence of 1.3-4.1 per 100,000 adults. However, recent large-scale genomic studies have revealed a high prevalence of pathogenic NOTCH3 variants among the general populati...
Source: Journal of Clinical Neurology - January 6, 2023 Category: Neurology Authors: Yumi Yamamoto Yi-Chu Liao Yi-Chung Lee Masafumi Ihara Jay Chol Choi Source Type: research

Relationship Between MicroRNA Signature and Arterial Stiffness in Patients With Ischemic Stroke
CONCLUSIONS: The expression level of let-7i was independently related to arterial stiffness in patients with cerebral infarction, suggesting that it plays a pathophysiological role in atherosclerosis.PMID:36606643 | DOI:10.3988/jcn.2023.19.1.28
Source: Journal of Clinical Neurology - January 6, 2023 Category: Neurology Authors: Sang-Jin Lee Jeong-Min Kim Eun Sun Lee Kwang-Yeol Park Hye Ryoun Kim Source Type: research

Update on the Epidemiology, Pathogenesis, and Biomarkers of Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy
J Clin Neurol. 2023 Jan;19(1):12-27. doi: 10.3988/jcn.2023.19.1.12.ABSTRACTCerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic disorder of the cerebral small blood vessels. It is caused by mutations in the NOTCH3 gene on chromosome 19, and more than 280 distinct pathogenic mutations have been reported to date. CADASIL was once considered a very rare disease with an estimated prevalence of 1.3-4.1 per 100,000 adults. However, recent large-scale genomic studies have revealed a high prevalence of pathogenic NOTCH3 variants among the general populati...
Source: Journal of Clinical Neurology - January 6, 2023 Category: Neurology Authors: Yumi Yamamoto Yi-Chu Liao Yi-Chung Lee Masafumi Ihara Jay Chol Choi Source Type: research

Collateral Flow in Magnetic Resonance Angiography: Prognostic Value for Vertebrobasilar Stenosis With Stroke Recurrence
CONCLUSIONS: The new PCoA-P1 score appears to provide improve predictions of stroke recurrence in patients with IVBAS.PMID:36062767 | PMC:PMC9444559 | DOI:10.3988/jcn.2022.18.5.507
Source: Journal of Clinical Neurology - September 5, 2022 Category: Neurology Authors: Long Yan Ying Yu Kaijiang Kang Zhikai Hou Min Wan Weilun Fu Rongrong Cui Yongjun Wang Zhongrong Miao Xin Lou Ning Ma Source Type: research