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Endovascular treatment of wide-necked intracranial aneurysms using the Nautilus Intrasaccular System: initial case series of 41 patients at a single center
Conclusion This study demonstrates good safety and effectiveness using the Nautilus Intrasaccular System to treat both ruptured and unruptured intracranial aneurysms. Larger studies are needed to confirm these findings.
Source: Journal of NeuroInterventional Surgery - September 15, 2023 Category: Neurosurgery Authors: Sirakov, A., Bhogal, P., Sirakova, K., Penkov, M., Minkin, K., Ninov, K., Hristov, H., Hadzhiyanev, A., Karakostov, V., Sirakov, S. Tags: Open access, New devices New devices and techniques Source Type: research

P010/89 Endovascular treatment of carotid petrous segment giant saccular aneurysm presented with cerebral ischemia
ConclusionEndovascular treatment using flow diverter with additional coiling seems to be the first choice of treatment in selected patients with petrous segment carotid aneurysms.Disclosure of InterestNothing to disclose
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Lazovic, L., Alsarraf, L., Andrejevic, A., Bosnjakovic, P. Tags: 4.3 CASE PROPOSAL - Acute ischemic stroke Source Type: research

E-078 Advancement in coil technology for treatment of brain aneurysms
ConclusionThis study concludes that is SMART coil system is safe and efficacious for the use in Endovascular treatment of intracranial aneurysms. The smart coil system is promising in the treatment of wide spectrum of intracranial aneurysms. The result of follow up angiographic data should reflect the high packing density and will be published when completed.Disclosures S. Khairandish: None. S. Pakbaz: None. M. McManus: None. G. Ammirati: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Khairandish, S., Pakbaz, S., McManus, M., Ammirati, G. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

O-063 First U.S. multicenter experience using the pipeline flex embolization device with shield technology for treatment of intracranial aneurysms
ConclusionOur study is the first to report the early experience with the newly FDA-approved PED Flex with Shield technology amongst US centers. Our results are comparable with non-US, international studies showing a high technical success rate and safe peri-procedural angiographic and patient outcome. Longer follow-up will be needed to provide more robust data on angiographic and patient outcomes.Disclosures A. Kuhn: None. J. Singh: None. A. Abdelsalam: None. V. Saini: None. J. Burks: None. G. Cortez: None. R. Abbas: None. M. Pervez: None. H. Saei: None. S. Burke: None. M. Salem: None. J. Vivanco-Suarez: None. R. Kutcher-D...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Kuhn, A., Singh, J., Abdelsalam, A., Saini, V., Burks, J., Cortez, G., Abbas, R., Pervez, M., Saei, H., Burke, S., Salem, M., Vivanco-Suarez, J., Kutcher-Diaz, R., Bounajem, M., Naragum, V., Massari, F., Marwah, S., Gounis, M., Hassan, A., Malek, A., Dabu Tags: SNIS 20th annual meeting oral abstracts Source Type: research

E-261 Variability of response on prophylactic prasugrel for endovascular treatment of intracranial aneurysms: clinical implications
ConclusionIn the neurointerventional field, high BMI and prior use of antithrombotic agents were related to HTPR, and low BMI was associated with LTPR on prophylactic prasugrel. High hematocrit levels decreased the risk of HTPR. When preparing endovascular treatment for intracranial aneurysms, attention to patients with these clinical features is required to address the possibility of ischemic or bleeding complications.Abstract E-261 Table 1Risk factor analysis of high on-treatment platelet reactivity (HTPR) Variables Univariate Analysis Multivariate Analysis OR (95% CI) P OR (95% CI) P Age 1.02 (0.97-1.06) 0.53 Female o...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Son, Y., Hong, N. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-262 Pipeline embolization device for the treatment of unruptured intracranial saccular aneurysms: a systematic review and meta-analysis of long-term outcomes
ConclusionThe PED is a safe and effective method to treat intracranial saccular aneurysms: The long-term complete occlusion rate is high (81%), with almost a quarter of the patients persist with residual filling. Even longer follow-ups are expected to show higher occlusion rates.Disclosures A. Ghaith: None. J. Rios-Zermeno: None. E. Greco: None. M. Bydon: None. R. Tawk: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Ghaith, A., Rios-Zermeno, J., Greco, E., Bydon, M., Tawk, R. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-025 The rate and predictors of 30-day readmission in patients treated for cerebral aneurysms: a large single-center study
ConclusionIn our study, risk factors for 30-day readmission were increasing BMI, cancer, increasing aneurysm width, and anticoagulation use. Future studies should focus on aneurysm dimensions and the use of blood thinners as the literature pertaining these predictors is still scarce.Abstract E-025 Table 1 Variables N(%) 30-day Readmission 36 (6.6) Cause of Readmission: Infection Stroke Re-Rupture Wound Dehiscence Seizures CSF Leak Hydrocephalus Headache Wound Area Swelling Groin Hematoma Pseudo meningocele 9 (25)11 (30.6)1 (2.8)1 (2.8)1 (2.8)1 (2.8)1 (2.8)7 (19.4)2 (5.6)1 (2.8)1 (2.8) Causes and Rate of ReadmissionAbstrac...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: El Naamani, K., Hunt, A., Jain, P., Lawall, C., Yudkoff, C., El Fadel, O., Ghanem, M., Momin, A., Atallah, E., Abbas, R., Zakar, R., Tjoumakaris, S., Gooch, M., Herial, N., Zarzour, H., Schmidt, R., Rosenwasser, R., Jabbour, P. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-065 Interim safety and occlusion outcomes of endovascular treatment of large intracranial aneurysms in the sterling registry
ConclusionEarly results from the STERLING registry for large aneurysms are promising. Adequate occlusion per Independent Core Lab was achieved in 86.7% and retreatment rates were relatively low over 1-year follow-up. A good functional outcome was achieved in 85.7% of patientsDisclosures O. Zaidat: 1; C; Stryker, Medtronic, Cerenovus, Penumbra, and Genentech. 2; C; Stryker, Medtronic, Cerenovus, Penumbra, and Neuravi. 4; C; ownership interest in Galaxy Therapeutics LLC;. 6; C; honoraria from Codman,Stryker,Penumbra, Medtronic. serves on the endovascular committee as co-chair for NIH StrokeNet Consortium; has served as an ex...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Zaidat, O., Ashouri, Y., Starke, R., Puri, A., Jankowitz, B., Yoo, A., Marnat, G., Kulcsar, Z., Sugiu, K., Jahshan, S., Machi, P., Pero, G., Castro, S., Howington, J., Schirmer, C., Kilburg, C., Chivot, C., Al-Mufti, F., Da Ros, V., Gory, B., Yao, T., Pol Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

Clinical experience with the Bendit steerable microcatheter: a new paradigm for endovascular treatment
Conclusions Our initial clinical experience with the Bendit21 microcatheter demonstrates its usefulness in achieving technical success in patients with challenging neurovascular conditions.
Source: Journal of NeuroInterventional Surgery - July 14, 2023 Category: Neurosurgery Authors: Killer-Oberpfalzer, M., Chapot, R., Orion, D., Barr, J. D., Cabiri, O., Berenstein, A. Tags: Open access, New devices New devices and techniques Source Type: research

Endovascular coiling versus neurosurgical clipping for treatment of ruptured and unruptured intracranial aneurysms during pregnancy and postpartum period
Conclusions Most pregnant and postpartum patients are treated with EC for both ruptured and unruptured IA. For treatment of ruptured IA, EC is independently associated with a lower risk of perioperative ischemic stroke, but other in-hospital complications and mortality are comparable between EC and NC.
Source: Journal of NeuroInterventional Surgery - March 14, 2023 Category: Neurosurgery Authors: Garg, A., Elmashala, A., Roeder, H., Ortega-Gutierrez, S. Tags: Editor''s choice, Hemorrhagic stroke Source Type: research

Antiplatelet therapy for standalone coiling of ruptured intracranial aneurysms: a systematic review and meta-analysis
Conclusions Although this study showed no beneficial effect of AT on clinical outcomes, the results suggest that AT could be combined with standalone coiling to avoid thromboembolism during the perioperative period. A large prospective study and/or an additional meta-analysis would be required to further investigate how AT benefits standalone coil embolization in aSAH.
Source: Journal of NeuroInterventional Surgery - November 14, 2022 Category: Neurosurgery Authors: Takase, H., Tatezuki, J., Salem, M. M., Tayama, K., Nakamura, Y., Burkhardt, J.-K., Yamamoto, T. Tags: Hemorrhagic stroke Source Type: research

Patient and aneurysm factors associated with aneurysm recanalization after coiling
Conclusions Several factors are identified by the ARETA study as playing a role in aneurysm recanalization after coiling: current smoking, aneurysm status (ruptured), aneurysm size (≥10 mm), neck size (wide neck), and aneurysm location (middle cerebral artery). This finding has important consequences in clinical practice. Trial registration number URL: http://www.clinicaltrials.gov; Unique Identifier: NCT01942512.
Source: Journal of NeuroInterventional Surgery - October 14, 2022 Category: Neurosurgery Authors: Pierot, L., Barbe, C., Thierry, A., Bala, F., Eugene, F., Cognard, C., Herbreteau, D., Velasco, S., Chabert, E., Desal, H., Aggour, M., Rodriguez-Regent, C., Gallas, S., Sedat, J., Marnat, G., Sourour, N., Consoli, A., Papagiannaki, C., Spelle, L., White, Tags: Open access, Hemorrhagic stroke Source Type: research

Endovascular treatment of ruptured anterior communicating aneurysms: a 17-year institutional experience with coil embolization
Conclusions Endovascular treatment of ruptured ACoA aneurysms is safe and is associated with low mortality and retreatment rates. Younger patients with favorable functional status and larger aneurysm size are more likely to be retreated. Ruptured aneurysms <4 mm, although prevalent in the study (29%), never required retreatment.
Source: Journal of NeuroInterventional Surgery - September 14, 2022 Category: Neurosurgery Authors: Catapano, J. S., Karahalios, K., Rumalla, K., Srinivasan, V. M., Rutledge, C., Baranoski, J. F., Cole, T. S., Jadhav, A. P., Ducruet, A. F., Albuquerque, F. C. Tags: Hemorrhagic stroke Source Type: research

O10 The necessity of monitoring platelet response and adjusting antiplatelet agents for endovascular treatment of unruptured intracranial aneurysms: a single-center, retrospective, cohort study
ConclusionActive monitoring and adjustment antiplatelet agents did not reduce ischemic complications in endovascular treatment; however, tended to reduce the ischemic complication, especially in flow diversion. Low-dose prasugrel may be feasible without increasing hemorrhage in the endovascular treatment of unruptured intracranial aneurysms.ReferencesLi W. Effect of Adjusted Antiplatelet Therapy on Preventing Ischemic Events after Stenting for Intracranial Aneurysms. Stroke. 2021 Dec;52(12):3815–3825. DOI: 10.1161/StrokeAHA.120.032989. EPUB 2021 SEP 20. PMID: 34538087.Hwang G. Standard vs Modified Antiplatelet Prepar...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Moon, E., Kwon, B., Song, Y., Lee, D., Park, J., Suh, D. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

P25 Short- and long-term mortality of subarachnoid hemorrhage according to hospital volume and severity using a nationwide multicenter stroke registry
ConclusionShort- and long-term mortality in patients with SAH differed according to hospital volume. In the modern endovascular era, clipping and coiling can lead to better outcomes in facilities with high stroke-care capabilities.ReferencesPobereskin LH. Incidence and outcome of subarachnoid haemorrhage: a retrospective population based study. J Neurol Neurosurg Psychiatry 2001;70:340–3. DOI:10.1136/JNNP.70.3.340.Lee JY, Heo NH, Lee MR, Ahn JM, Oh HJ, Shim JJ, et al. Short and long-term outcomes of subarachnoid hemorrhage treatment according to hospital volume in korea: a nationwide multicenter registry. J Korean Me...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Oh, J. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

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