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Source: American Journal of Translational Research
Education: Study
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Total 871 results found since Jan 2013.
Association between HMGB1 genetic variants and ischemic stroke susceptibility, onset age, and recurrence risk among Chinese Han individuals
CONCLUSIONS: Our study provided evidence for the association between HMGB1 polymorphisms and ischemic stroke susceptibility and recurrence, indicating that HMGB1 gene variants may be potential markers for first and secondary stroke prevention.PMID:37303653 | PMC:PMC10251027
Source: American Journal of Translational Research - June 12, 2023 Category: Research Authors: Luying Qiu Long Li Zhiyi He Fang Liu Shumin Deng Yanzhe Wang Source Type: research
Different impairment of immune and inflammation functions in short and long-term after ischemic stroke.
This study aims to explore the difference of global gene expression profiles and impairment of biological functions between short-term and long-term after stroke onset. We compared three short-term (3 h, 5 h and 24 h) and a long-term (6-month) gene expression levels by a multi-platform microarray data integration method. RankProd was used to calculate the differentially expressed genes between stroke patients and controls. DAVID Bioinformatics Resources was utilized to determine affected biological functions. Consensus cluster and hierarchical cluster methods were employed to compare the gene expression patterns of the com...
Source: American Journal of Translational Research - March 27, 2017 Category: Research Tags: Am J Transl Res Source Type: research
T-lymphocyte subsets as a predictive biomarker for stroke-associated pneumonia.
Authors: Feng HX, Cheng Y, Zhu W, Jiang LL, Dong XF, Gui Q, Wu GH, Xu QR, Shen MQ, Cheng QZ
Abstract
The aim of this study was to facilitate the clinical treatment and prognosis of stroke-associated pneumonia (SAP) by examining changes in T-lymphocyte subsets. Stroke patients admitted in Suzhou Hospital between 2014 and 2016 participated in the study. Patients were divided into a pneumonia group (50 patients) and a non-pneumonia group (254 patients) based on a diagnosis of pneumonia. Information regarding risk factors for ischemic stroke was collected from all patients using a questionnaire. Compared with non-SAP p...
Source: American Journal of Translational Research - January 24, 2019 Category: Research Tags: Am J Transl Res Source Type: research
Neuropathic pain releasing calcitonin gene related peptide protects against stroke in rats.
Authors: Wang Y, Liu Z, Ge X, Hu X, Cao X, Li L, Xia J, Li F, Gao L
Abstract
Neuropathic pain (NPP) is deemed as a potential risk of stroke; however, recent pieces of evidence showed that calcitonin gene-related peptide is involving in pain progression as well as organ protection. The mechanisms underlying the neuroprotection of calcitonin gene-related peptide are yet poorly described with respect to stroke. The present study showed that the elevated level of calcitonin gene-related peptide-induced by NPP exerts a protective effect against stroke in rats, which was further confirmed in vivo and vitro via mitigation...
Source: American Journal of Translational Research - February 15, 2020 Category: Research Tags: Am J Transl Res Source Type: research
Analysis of influencing factors of rehabilitation treatment effect in patients with first-episode stroke
CONCLUSION: Age, the number of residual symptoms, depression status, attitude towards rehabilitation treatment, starting time of rehabilitation treatment, rehabilitation treatment duration, and family environment score are independent factors for rehabilitation treatment effect in patients with first-episode stroke.PMID:35035747 | PMC:PMC8748090
Source: American Journal of Translational Research - January 17, 2022 Category: Research Authors: Qianfeng Yan Xiangming Wang Yun Zhang Huijun Zhang Lipeng Zhao Source Type: research
