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Source: Journal of Clinical Neuroscience
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Total 163 results found since Jan 2013.
Treatment of patients with mild acute ischemic stroke and associated large vessel occlusion
Publication date: Available online 3 April 2016 Source:Journal of Clinical Neuroscience Author(s): Russell Cerejo, Esteban Cheng-Ching, Ferdinand Hui, M. Shazam Hussain, Ken Uchino, Jennifer Bullen, Gabor Toth Several recent studies have shown that patients presenting with mild acute ischemic stroke (mAIS) symptoms may have an unfavorable natural history. The presence of associated large vessel occlusion (LVO) may lead to even worse outcomes, but most mAIS patients are still excluded from acute stroke treatment (AST). A retrospective review of patients with acute ischemic stroke presenting to our institution betwe...
Source: Journal of Clinical Neuroscience - April 3, 2016 Category: Neuroscience Source Type: research
Microvascular decompression for elderly patients with trigeminal neuralgia
Publication date: Available online 2 March 2016 Source:Journal of Clinical Neuroscience Author(s): Kevin Phan, Prashanth J. Rao, Mark Dexter Microvascular decompression (MVD) has been demonstrated to be an excellent surgical treatment approach in younger patients with trigeminal neuralgia (TN). However, it is not clear whether there are additional morbidity and mortality risks for MVD in the elderly population. We performed a systematic literature review using six electronic databases for studies that compared outcomes for MVD for TN in elderly (cut-off ⩾60, 65, 70years) versus younger populations. Outcomes examined...
Source: Journal of Clinical Neuroscience - March 2, 2016 Category: Neuroscience Source Type: research
Airplane stroke syndrome
We describe the patient, stroke, and flight characteristics. Over the study period, 131 million passengers arrived at Melbourne airport. Our centre admitted 5727 stroke patients, of whom 42 (0.73%) had flight-related strokes. Flight-related stroke patients were younger (median age 65 versus 73, p<0.001), had similar stroke severity, and received intravenous thrombolysis more often than non-flight-related stroke patients. Seven patients had flight-related intracerebral haemorrhage. The aetiology of the ischaemic strokes was cardioembolic in 14/35 (40%), including seven patients with confirmed PFO, one with atrial sep...
Source: Journal of Clinical Neuroscience - February 20, 2016 Category: Neuroscience Source Type: research
Intravenous thrombolysis, mechanical embolectomy, and intracranial stenting for hyperacute ischemic stroke in a patient with moyamoya disease
Publication date: Available online 17 February 2016 Source:Journal of Clinical Neuroscience Author(s): Debora S. Argetsinger, Jeffrey W. Miller, Jeffrey J. Fletcher The Japanese translation of moyamoya means “puff of smoke” and refers to the angiographic appearance of dilated collateral vessels seen during chronic progressive narrowing of the intracranial supraclinoid portions of the internal carotid arteries. Despite cerebral ischemia being the most common presenting symptom, 20% to 40% of adults suffer a hemorrhagic stroke. Due to the lack of evidence and histopathologic findings, intravenous and endovascular re...
Source: Journal of Clinical Neuroscience - February 18, 2016 Category: Neuroscience Source Type: research
Isolated asymptomatic pulmonary arteriovenous malformation presenting with ischaemic stroke
Publication date: Available online 17 February 2016 Source:Journal of Clinical Neuroscience Author(s): Kelly L. Bertram, Anoop Madan, Judith Frayne Young onset stroke is uncommon, and may be due to conditions other than traditional vascular risk factors. A 42-year-old woman with an ischaemic stroke was found to have left atrial bubble study positivity on transthoracic echocardiogram (TTE) suggestive of patent foramen ovale, however she also had low peripheral oxygen saturation. Investigation revealed an isolated pulmonary arteriovenous malformation (PAVM), visible on admission chest radiograph. This can cause embolic ...
Source: Journal of Clinical Neuroscience - February 18, 2016 Category: Neuroscience Source Type: research
Ten year clinical experience with stroke and cerebral vasculitis
Publication date: Available online 8 January 2016 Source:Journal of Clinical Neuroscience Author(s): Peter A. Kempster, Catriona A. McLean, Thanh G. Phan Angiitis of the central nervous system (CNS) is difficult to diagnose but potentially fatal. When stroke occurs in a younger individual or is associated with multiple infarcts on imaging, clinicians must decide how far to pursue a possible diagnosis of vasculitis. The aim of this study is to establish the prevalence of primary and secondary cerebral angiitis among patients presenting with stroke. Hospital attendances over a 10year period were surveyed by searching fo...
Source: Journal of Clinical Neuroscience - January 11, 2016 Category: Neuroscience Source Type: research
Flexor and extensor muscle tone evaluated using the quantitative pendulum test in stroke and parkinsonian patients
In conclusion, the hypertonia of parkinsonian and stroke patients could not be differentiated by the modified pendulum test; the elbow extensors showed a higher muscle tone in both control and patient groups; and hypertonia of both parkinsonian and stroke patients is velocity dependent.
Source: Journal of Clinical Neuroscience - January 11, 2016 Category: Neuroscience Source Type: research
Holmes’ tremor as a delayed complication of thalamic stroke
We present a 75-year-old man who developed a disabling tremor 1year after a posterolateral thalamic stroke. This tremor had low frequency (3–4Hz), did not disappear on focus and was exacerbated by maintaining a static posture and on target pursuit, which made it very difficult to perform basic functions. MRI demonstrated an old ischemic lesion at the left posterolateral thalamus. Treatment with levodopa led to symptom control. Lesions in the midbrain, cerebellum and thalamus may cause Holmes’ tremor. Delayed onset of symptoms is usually seen, sometimes appearing 2years after the original injury. This may be due to matu...
Source: Journal of Clinical Neuroscience - November 21, 2015 Category: Neuroscience Source Type: research
Pure agraphia after infarction in the superior and middle portions of the left precentral gyrus: Dissociation between Kanji and Kana
Publication date: Available online 17 November 2015 Source:Journal of Clinical Neuroscience Author(s): Yoshiko Kurosaki, Ryusaku Hashimoto, Hiroshi Tatsumi, Kazuo Hadano The present study describes a Japanese patient with pure agraphia displaying differential disturbances in processing Kanji (morphogram) and Kana (syllabogram) letters after an infarction in the middle and superior portions of the left precentral gyrus. Kana errors reflected the patient’s difficulty with retrieving both motor and visual letter images, whereas Kanji errors included partial letter stroke omissions or additions. This present case sugge...
Source: Journal of Clinical Neuroscience - November 17, 2015 Category: Neuroscience Source Type: research
Transorbital neuroendoscopic surgery for the treatment of skull base lesions
In this study, we aimed to retrospectively review the largest experience to our knowledge with regards to surgical outcomes of skull base pathologies treated with a TONES procedure. Forty patients (aged 3–89years) underwent 45 TONES procedures between the years of 2006–2013. Pathologies were cerebrospinal fluid leak repair (n=16), traumatic fracture (n=8), tumor (n=11), meningoencephalocele (n=5), hematoma (n=1), and infection (n=4). Three patients had a persistent complication at 3months, including a case each of enophthalmos (unnoticed by patient), epiphora (delayed presentation at 2months requiring dacryocystorhinos...
Source: Journal of Clinical Neuroscience - November 10, 2015 Category: Neuroscience Source Type: research
Diagnostic accuracy of EEG changes during carotid endarterectomy in predicting perioperative strokes
Publication date: Available online 21 October 2015 Source:Journal of Clinical Neuroscience Author(s): Parthasarathy D. Thirumala, Karthy Thiagarajan, Satyanarayana Gedela, Donald J. Crammond, Jeffrey R. Balzer The 30 day stroke rate following carotid endarterectomy (CEA) ranges between 2–6%. Such periprocedural strokes are associated with a three-fold increased risk of mortality. Our primary aim was to determine the diagnostic accuracy of electroencephalogram (EEG) in predicting perioperative strokes through meta-analysis of existing literature. An extensive search for relevant literature was undertaken using PubM...
Source: Journal of Clinical Neuroscience - October 22, 2015 Category: Neuroscience Source Type: research
Electrocardiograph abnormalities in intracerebral hemorrhage
This study investigated the prevalence and type of electrocardiography (ECG) abnormalities, and their possible association with the clinical/radiological findings in 118 consecutive patients with non-traumatic, non-neoplastic intracerebral hemorrhage (ICH). ECG frequently demonstrates abnormalities in patients with ischemic stroke and subarachnoid hemorrhage, but little is known of ECG changes in ICH patients. Clinical and radiological information was retrospectively reviewed. ECG recordings that were obtained within 24hours of the initial hemorrhage were analyzed. Sixty-six patients (56%) had one or more ECG abnormalities...
Source: Journal of Clinical Neuroscience - September 11, 2015 Category: Neuroscience Source Type: research
Changes in differential gene expression during a fatal stroke
We present a young woman (with an identical twin sister) who arrived at the Emergency Department (ED) within 1hour of her initial stroke symptoms. Previous microarray studies have demonstrated differential expression of multiple genes between stroke patients and healthy controls. However, for many of these studies there is a significant delay between the initial symptoms and collection of blood samples, potentially leaving the important early activators/regulators of the inflammatory response unrecognised. Blood samples were collected from the patient for an analysis of differential gene expression over time during the evo...
Source: Journal of Clinical Neuroscience - August 29, 2015 Category: Neuroscience Source Type: research
Impact of early enteral nutrition on short term prognosis after acute stroke
Publication date: Available online 14 July 2015 Source:Journal of Clinical Neuroscience Author(s): Tianheng Zheng , Xinpu Zhu , Huazheng Liang , Haixia Huang , Jiandao Yang , Shaoshi Wang We hypothesized that early enteral nutritional support would improve the short term prognosis of acute stroke patients with dysphagia, demonstrated by lower malnutrition rates, lower complication rates, and lower National Institutes of Health Stroke Scale (NIHSS) scores at 90days post stroke. Nutrition support is an essential element in the care of stroke patients and many studies have investigated the effect of specific nutritional ele...
Source: Journal of Clinical Neuroscience - July 14, 2015 Category: Neuroscience Source Type: research
Muscle haematoma due to antithrombotic treatment for ischaemic stroke
Publication date: July 2015 Source:Journal of Clinical Neuroscience, Volume 22, Issue 7 Author(s): Akiyuki Hiraga , Yoko Nakagawa , Ikuo Kamitsukasa , Takeshi Suzuki , Satoshi Kuwabara The purpose of this study was to evaluate the incidence and clinical features of muscle haematoma in ischaemic stroke patients. Muscle haematomas are rare complications that occur during antithrombotic treatment for acute ischaemic stroke. Clinical and laboratory records of ischaemic stroke patients with muscle haematomas in the last 3.5years were retrospectively reviewed. Muscular haematoma developed in three of 694 (0.4%) consecutive pat...
Source: Journal of Clinical Neuroscience - May 31, 2015 Category: Neuroscience Source Type: research
