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Source: Journal of Stroke and Cerebrovascular Diseases
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Total 3074 results found since Jan 2013.
Mechanism of Acute Ischemic Stroke in Patients with Severe Middle Cerebral Artery Atherosclerotic Disease
Conclusions: In patients with severe MCA ICAD, the mechanism of stroke is multifactorial, but hemodynamic insufficiency plays a significant role. This finding is important in selecting a subgroup of patients who may benefit from revascularization.
Source: Journal of Stroke and Cerebrovascular Diseases - January 13, 2014 Category: Neurology Authors: Jordan S. Dubow, Elliott Salamon, Edward Greenberg, Athos Patsalides Tags: Original Articles Source Type: research
Physical Activity Early after Stroke and Its Association to Functional Outcome 3 Months Later
Conclusions: This study confirms that time in bed in the early phase is associated with poor functional outcome 3 months later, indicating that too much bed rest should be avoided in the early phase after stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - February 14, 2014 Category: Neurology Authors: Torunn Askim, Julie Bernhardt, Øyvind Salvesen, Bent Indredavik Tags: Original Articles Source Type: research
A Matched Comparison of Eptifibatide Plus rt-PA Versus rt-PA Alone in Acute Ischemic Stroke
Conclusions: The safety and direction of effect of eptifibatide plus rt-PA were confirmed. A phase III trial is needed to determine the efficacy of eptifibatide plus rt-PA for improving long-term outcomes after AIS.
Source: Journal of Stroke and Cerebrovascular Diseases - February 19, 2014 Category: Neurology Authors: Opeolu Adeoye, William A. Knight, Jane Khoury, Pamela A. Schmit, Heidi Sucharew, Joseph P. Broderick, Arthur M. Pancioli, CLEAR-ER Investigators Tags: Original Articles Source Type: research
Alpha 1-Antitrypsin Therapy Mitigated Ischemic Stroke Damage in Rats
Our objective is to develop a new therapy for the treatment of stroke. Currently, the only effective therapy for acute ischemic stroke is the thrombolytic agent recombinant tissue plasminogen activator. α1-Antitrypsin (AAT), a serine proteinase inhibitor with potent anti-inflammatory, anti-apoptotic, antimicrobial, and cytoprotective activities, could be beneficial in stroke. The goal of this study is to test whether AAT can improve ischemic stroke outcome in an established rat model. Middle cerebral artery occlusion was induced in male rats via intracranial (i.c.) microinjection of endothelin-1. Five to 10 minutes after...
Source: Journal of Stroke and Cerebrovascular Diseases - March 3, 2014 Category: Neurology Authors: Huong L. Moldthan, Aaron C. Hirko, Jeffrey S. Thinschmidt, Maria B. Grant, Zhimin Li, Joanna Peris, Yuanqing Lu, Ahmed S. Elshikha, Michael A. King, Jeffrey A. Hughes, Sihong Song Tags: Original Articles Source Type: research
Characteristics of Wake-up Stroke
Conclusions: WUS is more likely to result from small-vessel disease mechanism. Poorer cholesterol profile and frequent snoring may contribute to WUS.
Source: Journal of Stroke and Cerebrovascular Diseases - December 20, 2013 Category: Neurology Authors: Aki Tanimoto, Prachi Mehndiratta, Brian B. Koo Tags: Original Articles Source Type: research
Impact of Thyroid Autoantibodies on Functional Outcome in Patients with Acute Ischemic Stroke
Conclusions: This study showed that elevated thyroid autoantibodies were independently associated with unfavorable outcome in patients with acute ischemic stroke. We speculate that immune-mediated vascular damage may contribute to the increased risk of unfavorable outcome by providing insufficient cerebral blood flow to the ischemic area.
Source: Journal of Stroke and Cerebrovascular Diseases - May 5, 2014 Category: Neurology Authors: Han-Jin Cho, Sang-Soo Kim, Sang-Min Sung, Dae-Soo Jung Tags: Original Articles Source Type: research
A Comparative Study of Dual versus Monoantiplatelet Therapy in Patients with Acute Large-Artery Atherosclerosis Stroke
Background: Antiplatelet drugs are recommended for patients with acute noncardioembolic stroke. However, few randomized clinical trials have investigated the safety and efficacy of dual antiplatelet therapy for these patients. The aim of this study was to evaluate the effects of treatment with clopidogrel and aspirin (combination therapy) and aspirin alone (monotherapy) on neurologic deterioration, platelet activation, and other short-term outcomes in patients with acute large-artery atherosclerosis stroke.Materials and Methods: Altogether 574 patients with acute (≤2 days) large-artery atherosclerosis stroke were random...
Source: Journal of Stroke and Cerebrovascular Diseases - April 15, 2014 Category: Neurology Authors: Xingyang Yi, Jing Lin, Chun Wang, Biao Zhang, Wanzhang Chi Tags: Original Articles Source Type: research
The Quality of Prehospital Ischemic Stroke Care: Compliance with Guidelines and Impact on In-hospital Stroke Response
This study examined performance measure compliance among EMS-transported stroke patients and the relationship between compliance and in-hospital stroke response.
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2014 Category: Neurology Authors: John Adam Oostema, Mojdeh Nasiri, Todd Chassee, Mathew J. Reeves Source Type: research
Association of Leukoaraiosis with Stroke Recurrence within 5 Years after Initial Stroke
In this study, we sought to identify whether LA contributes to the recurrence of certain subtypes of stroke at long term.
Source: Journal of Stroke and Cerebrovascular Diseases - December 19, 2014 Category: Neurology Authors: Emre Kumral, Halil Güllüoğlu, Naila Alakbarova, Bedriye Karaman, Emrah Emre Deveci, Aydın Bayramov, Dilek Evyapan, Figen Gökçay, Mehmet Orman Source Type: research
Poor Stroke Risk Perception despite Moderate Public Stroke Awareness: Insight from a Cross-sectional National Survey in Greece
Although stroke is the fourth cause of death in Western societies, public stroke awareness remains suboptimal. The aim of this study was to estimate stroke risk perception and stroke awareness in Greece through a cross-sectional telephone survey.
Source: Journal of Stroke and Cerebrovascular Diseases - February 11, 2015 Category: Neurology Authors: George Ntaios, Vasiliki Melikoki, George Perifanos, Kalliopi Perlepe, Fotios Gioulekas, Anastasia Karagiannaki, Ioanna Tsantzali, Chrysanthi Lazarou, Nikolaos Beradze, Evdoxia Poulianiti, Matina Poulikakou, Theofanis Palantzas, Stavrina Kaditi, Fay Perlep Source Type: research
The Obesity Paradox and Survivors of Ischemic Stroke
Although obesity is a risk factor for stroke and achieving normal weight is advocated to decrease stroke risk, the risk associated with obesity and weight loss after stroke has not been well established. The aim of this study was to assess the association of obesity at the time of stroke admission and weight loss after stroke with total mortality.
Source: Journal of Stroke and Cerebrovascular Diseases - April 9, 2015 Category: Neurology Authors: Peter Wohlfahrt, Francisco Lopez-Jimenez, Alena Krajcoviechova, Marie Jozifova, Otto Mayer, Jiri Vanek, Jan Filipovsky, Ernesto M. Llano, Renata Cifkova Source Type: research
Diabetes Is an Independent Risk Factor for Stroke Recurrence in Stroke Patients: A Meta-analysis
This study aimed to assess the association between diabetes and risk of stroke recurrence (especially ischemic stroke recurrence) and to evaluate whether diabetes was an independent predictor for stroke recurrence in stroke patients with diabetes.
Source: Journal of Stroke and Cerebrovascular Diseases - July 9, 2015 Category: Neurology Authors: Juan Shou, Li Zhou, Shanzhu Zhu, Xiangjie Zhang Source Type: research
External Validation of the Prestroke Independence, Sex, Age, National Institutes of Health Stroke Scale (ISAN) Score for Predicting Stroke-Associated Pneumonia in the Athens Stroke Registry
The Prestroke Independence, Sex, Age, National Institutes of Health Stroke Scale (ISAN) score was developed recently for predicting stroke-associated pneumonia (SAP), one of the most common complications after stroke. The aim of the present study was to externally validate the ISAN score.
Source: Journal of Stroke and Cerebrovascular Diseases - September 5, 2015 Category: Neurology Authors: Vasileios Papavasileiou, Haralampos Milionis, Craig J. Smith, Konstantinos Makaritsis, Benjamin D. Bray, Patrik Michel, Efstathios Manios, Konstantinos Vemmos, George Ntaios Source Type: research
Stroke Risk Perception in Atrial Fibrillation Patients is not Associated with Clinical Stroke Risk
Clinical risk stratification models, such as the CHA2DS2-VASc, are used to assess stroke risk in atrial fibrillation (AF) patients. No study has yet investigated whether and to which extent these patients have a realistic perception of their personal stroke risk. The purpose of this study was to investigate and describe the association between AF patients' stroke risk perception and clinical stroke risk.
Source: Journal of Stroke and Cerebrovascular Diseases - September 11, 2015 Category: Neurology Authors: Anders Fournaise, Jane Skov, Else-Marie Bladbjerg, Anja Leppin Source Type: research
Tobacco Use and Cryptogenic Stroke in Young Adults
Objective: Cryptogenic stroke is the leading subtype of ischemic stroke in the young. We sought to evaluate the association between traditional cardiovascular risk factors and cryptogenic stroke by using a case–control study. Methods: Patients aged 18-54 years, consecutively treated for first-ever cryptogenic ischemic stroke in an academic stroke unit, were compared with subjects from the general population living in the same geographic area. Control subjects were matched for age and sex with patients.
Source: Journal of Stroke and Cerebrovascular Diseases - October 5, 2015 Category: Neurology Authors: Aude Jaffre, Jean Bernard Ruidavets, Nathalie Nasr, Brigitte Guidolin, Jean Ferrieres, Vincent Larrue Source Type: research
