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Source: Journal of Stroke and Cerebrovascular Diseases
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Total 3074 results found since Jan 2013.

Investigation of Vaspin Level in Patients with Acute Ischemic Stroke
This study was intended to investigate the relation between vaspin and stroke and stroke and other risk factors.Methods: A total of 50 patients with stroke, as 28 men (56%) and 22 women (44%), and a total of 50 healthy individuals, as 25 men (50%) and 25 women (50%), were enrolled in the study. Blood samples were taken in the acute period (first 48 hours) in the patient group, and serum vaspin levels were measured. Vaspin level was also measured in the control group. The association of vaspin with the lipid parameters, gender, and the severity of internal carotid artery (ICA) stenosis in the patient group was evaluated. S...
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2013 Category: Neurology Authors: Hasan S. Cura, Hasan H. Özdemir, Caner F. Demir, Serpil Bulut, Nevin İlhan, Mehmet Fatih Inci Tags: Original Articles Source Type: research

Early Mobilization after Acute Stroke
Conclusions: Neither time to mobilization nor any other candidate variable was associated with good outcome 3 months poststroke.
Source: Journal of Stroke and Cerebrovascular Diseases - May 15, 2013 Category: Neurology Authors: Antje Sundseth, Bente Thommessen, Ole Morten Rønning Tags: Original Articles Source Type: research

The Impact of World and European Football Cups on Stroke in the Population of Dijon, France: A Longitudinal Study from 1986 to 2006
Conclusions: Watching European football competitions had a positive impact in the city of Dijon with a decrease of stroke numbers. European championship is possibly associated with higher television audience and long-lasting euphoria although other factors may be involved. Further studies using nationwide data are recommended to validate these findings.
Source: Journal of Stroke and Cerebrovascular Diseases - December 9, 2013 Category: Neurology Authors: Corine Aboa-Eboulé, Yannick Béjot, Jonathan Cottenet, Mehni Khellaf, Agnès Jacquin, Jérôme Durier, Olivier Rouaud, Marie Hervieu-Begue, Guy-Victor Osseby, Maurice Giroud, Catherine Quantin Tags: Original Articles Source Type: research

A Blood-based Biomarker Panel to Detect Acute Stroke
Background: The aim of this study was to develop an adjunctive, peripheral biomarker test to differentiate ischemic strokes, intracranial hemorrhages (ICHs), and stroke mimics in the acute setting.Methods: Serum samples were collected from 167 patients who presented with an acute neurologic deficit within 24 hours of symptom onset. Patients were adjudicated to ischemic stroke, ICH, and mimic pathology groups based on clinical and radiographic findings. Samples were tested for levels of 262 potential markers. A multivariate Cox proportional hazards regression model of 5 biomarkers was built by stepwise selection and valida...
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2013 Category: Neurology Authors: Richa Sharma, Stephanie Macy, Kara Richardson, Yuliya Lokhnygina, Daniel T. Laskowitz Tags: Original Articles Source Type: research

Does Symptom Onset to Primary Stroke Center Time Goals Affect Stroke Outcome?
Background: Treating acute ischemic stroke (AIS) within 4.5 hours and door-to-needle time of less than 60 minutes may optimize recovery. It is unknown if onset to Primary Stroke Center (PSC) time goals affect outcome. The purpose of this study was to examine effects of symptom onset to PSC time goals on outcome.Methods: Analysis included prospectively collected data from the University of California San Diego Specialized Program of Treatment Research in Acute Stroke. All AIS patients treated with intravenous recombinant tissue plasminogen activator were included if treated within 270 minutes, and 90-day modified Rankin ...
Source: Journal of Stroke and Cerebrovascular Diseases - October 7, 2013 Category: Neurology Authors: Bryant Chee, Rema Raman, Karin Ernstrom, Amy K. Guzik, Thomas M. Hemmen, Karen S. Rapp, Brett C. Meyer, Dawn M. Meyer Tags: Original Articles Source Type: research

The Impact of Comprehensive Stroke Care Capacity on the Hospital Volume of Stroke Interventions: A Nationwide Study in Japan: J-ASPECT Study
We examined the effect of hospital characteristics, having a t-PA protocol, and the number of fulfilled CSC items (total CSC score) on the hospital volume of t-PA infusion, removal of intracerebral hemorrhage, and coiling and clipping of intracranial aneurysms performed in 2009.Results: Approximately 55% of hospitals responded to the survey. Facilities with t-PA protocols (85%) had a significantly higher likelihood of having 23 CSC items, for example, personnel (eg, neurosurgeons: 97.3% versus 66.1% and neurologists: 51.3% versus 27.7%), diagnostic (eg, digital cerebral angiography: 87.4% versus 43.2%), specific expertise...
Source: Journal of Stroke and Cerebrovascular Diseases - October 7, 2013 Category: Neurology Authors: Koji Iihara, Kunihiro Nishimura, Akiko Kada, Jyoji Nakagawara, Kazunori Toyoda, Kuniaki Ogasawara, Junichi Ono, Yoshiaki Shiokawa, Toru Aruga, Shigeru Miyachi, Izumi Nagata, Shinya Matsuda, Koichi B. Ishikawa, Akifumi Suzuki, Hisae Mori, Fumiaki Nakamura, Tags: Original Articles Source Type: research

Quality of Life after Lacunar Stroke: The Secondary Prevention of Small Subcortical Strokes Study
Background: We sought to describe the course and predictors of quality of life (QOL) after lacunar stroke. We hypothesized that there is a decline in QOL after recovery from lacunar stroke.Methods: The Secondary Prevention of Small Subcortical Strokes is a clinical trial in lacunar stroke patients with annual assessments of QOL with the stroke-specific QOL score. The overall score was used and analyzed as a continuous variable (range 0-5). We fit linear mixed models to assess the trend in QOL over time, assuming linearity of time, and adjusted for demographics, medical risk factors, cognitive factors, and functional status...
Source: Journal of Stroke and Cerebrovascular Diseases - October 30, 2013 Category: Neurology Authors: Mandip S. Dhamoon, Leslie A. McClure, Carole L. White, Helena Lau, Oscar Benavente, Mitchell S.V. Elkind Tags: Original Articles Source Type: research

Outcomes in People after Stroke Attending an Adapted Cardiac Rehabilitation Exercise Program: Does Time from Stroke Make a Difference?
The objectives of the present study are (1) to evaluate the effects of a CRP in participants with motor impairment after stroke and (2) to explore the effects of elapsed time from stroke on physiological/quality-of-life outcomes.Methods: The CRP included 24 weeks of resistance and aerobic training. Primary outcomes in 120 participants, 25.4 ± 42.3 (mean ± standard deviation) months after stroke, included 6-minute walk distance (6MWD), VO2peak, timed repeated sit-to-stand performance, and affected-side isometric knee extensor strength (IKES). Secondary measures included gait characteristics (cadence, step lengths, an...
Source: Journal of Stroke and Cerebrovascular Diseases - April 7, 2014 Category: Neurology Authors: Susan Marzolini, Ada Tang, William McIlroy, Paul I. Oh, Dina Brooks Tags: Original Articles Source Type: research

Spontaneous Swallow Frequency Compared with Clinical Screening in the Identification of Dysphagia in Acute Stroke
Conclusions: Spontaneous SFA has high potential to identify dysphagia in acute stroke with psychometric properties equal or superior to clinical screening protocols.
Source: Journal of Stroke and Cerebrovascular Diseases - August 4, 2014 Category: Neurology Authors: Michael A. Crary, Giselle D. Carnaby, Isaac Sia Tags: Original Articles Source Type: research

Association between Helicobacter pylori Infection and Stroke: A Meta-analysis of Prospective Observational Studies
Conclusions: In conclusion, our formal meta-analysis indicated no strong association between H. pylori infection and stroke, neither in those with cytotoxin-associated gene-A–positive infection. We believe that future epidemiologic studies of H. pylori and stroke are unlikely to be fruitful.
Source: Journal of Stroke and Cerebrovascular Diseases - September 29, 2014 Category: Neurology Authors: Min Yu, Yangbo Zhang, Zhen Yang, Jiangwu Ding, Chuan Xie, Nonghua Lu Tags: Original Articles Source Type: research

Association of Variants in KCNK17 Gene with Ischemic Stroke and Cerebral Hemorrhage in a Chinese Population
Conclusions: The T carrier of an SNP (rs12214600) is associated with reduced risk of cerebral hemorrhage in the Chinese population, together with previous findings that SNPs rs10947803 and rs12214600 in the KCNK17 gene are associated with hemorrhagic stroke, but none of the SNPs tested had an association with ischemic stroke. KCNK17 may be important in the pathogenesis of cerebral hemorrhage.
Source: Journal of Stroke and Cerebrovascular Diseases - September 1, 2014 Category: Neurology Authors: Lingbin He, Qingfeng Ma, Yongqin Wang, Xin Liu, Yuan Yuan, Yongzhi Zhang, Wenjing Ou, Lisheng Liu, Xuerui Tan, Xingyu Wang Tags: Original Articles Source Type: research

Predictors of Cholesterol and Lipoprotein(a) Testing in Children with Arterial Ischemic Stroke
The objective of this study is to identify predictors and modifiable barriers to lipid testing in pediatric stroke.Methods: In this cross-sectional analysis, children (28 days-18 years) with arterial ischemic stroke were identified from the International Pediatric Stroke Study registry (January 2003-April 2012). Analyzed predictors of recorded lipid or lipoprotein a (Lp(a)) testing were age, sex, race, ethnicity, body mass index (BMI) category, other stroke risk factors, country, US region, and recurrent thrombosis.Results: Among 1652 participants (median, 6 years [interquartile range, 1.7-12.7]; 59.0% male; 40.8% white;...
Source: Journal of Stroke and Cerebrovascular Diseases - September 1, 2014 Category: Neurology Authors: Sally Sultan, Nicole Schupf, Michael Dowling, Gabrielle DeVeber, Adam Kirton, Mitchell S.V. Elkind, IPSS Investigators Tags: Original Articles Source Type: research

The Second Elevation of Neuron-Specific Enolase Peak after Ischemic Stroke Is Associated with Hemorrhagic Transformation
Conclusions: Serial NSE analysis during the acute period of ischemic stroke is useful for monitoring hemorrhagic transformation and the blood-brain barrier disruption status.
Source: Journal of Stroke and Cerebrovascular Diseases - September 1, 2014 Category: Neurology Authors: Bum Joon Kim, Yeon-Jung Kim, Sung Ho Ahn, Na Young Kim, Dong-Wha Kang, Jong S. Kim, Sun U. Kwon Tags: Original Articles Source Type: research

Predicting Daily Use of the Affected Upper Extremity 1 Year after Stroke
The ultimate goal of upper extremity (UE) stroke rehabilitation is for the individual with stroke to return using their arms and hands during daily activities in their own environment. No studies have monitored arm use as individuals with stroke transition from rehabilitation to the home setting. This longitudinal study compared the functional ability and daily use of the affected UE of individuals with stroke between discharge to home and 12 months after stroke and predicted the UE daily use 12 months after stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - December 17, 2014 Category: Neurology Authors: Debbie Rand, Janice J. Eng Source Type: research

Acute Stroke Registry Malaysia, 2010-2014: Results from the National Neurology Registry
Background: Stroke remains a major health burden worldwide. The incidence and prevalence rates of stroke are decreasing in developed countries, an opposite trend is taking place in the Asia Pacific, where an increasing number of patients are being diagnosed with acute stroke. The results of the present study on acute stroke in multi-ethnic Malaysia will significantly contribute to the global stroke epidemiological data. We aimed to present epidemiological data of stroke including incidence and prevalence rates as well as associated risk factors from a prospective nationwide hospital-based registry from 2010 to 2014.
Source: Journal of Stroke and Cerebrovascular Diseases - August 31, 2015 Category: Neurology Authors: Zariah A. Aziz, Yvonne Y.L. Lee, Bahari Awang Ngah, Norsima Nafizah Sidek, Irene Looi, Md. Rafia Hanip, Hamidon B. Basri Source Type: research