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146. Excitatory deep transcranial magnetic stimulation with H-coil over the right homologous Broca’s region improves naming in chronic post-stroke aphasia
This study aimed to compare the effect of excitatory, inhibitory and sham rTMS delivered with H-coil over the right inferior frontal gyrus (IFG) in chronic aphasic patients. Five right-handed post-stroke aphasic patients underwent a picture naming task before and immediately after each of three sessions of rTMS: excitatory (10Hz), inhibitory (1Hz) and sham rTMS, in random sequence and separated by at least 1 week. Only the excitatory 10Hz stimulation was associated with a significant improvement in naming performance, (p=0.043) and was significantly more effective than 1Hz rTMS (p=0.043). A single session of excitatory dee...
Source: Clinical Neurophysiology - October 21, 2013 Category: Neuroscience Authors: R. Chieffo, F. Ferrari, P. Battista, E. Houdayer, A. Nuara, F. Alemanno, J. Abutalebi, A. Zangen, G. Comi, S.F. Cappa, L. Leocani Tags: Society Proceedings Source Type: research

Effects of Non-Invasive Brain Stimulation on Post-Stroke Dysphagia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Studies report that 50% to 81% of people who have a stroke experience swallowing problems (Hamdy, 2010; Meng et al., 2000). This impact is staggering when the cost implications and morbidity of post-stroke dysphagia are considered. Stroke patients with dysphagia cost more to treat (about $4,510 more per patient than a stroke patient without dysphagia) because their hospital stay is nearly doubled, they require more therapy, and they have more complications with worse outcomes (Bonilha et al., 2014; Altman et al., 2010).
Source: Clinical Neurophysiology - May 8, 2015 Category: Neuroscience Authors: Jessica M. Pisegna, Asako Kaneoka, William G. Pearson, Sandeep Kumar, Susan E. Langmore Source Type: research

Bilateral changes in muscle architecture of physically active people with chronic stroke: a quantitative muscle ultrasound study
Stroke is primarily regarded as a central nervous system (CNS) disorder, but post-stroke structural changes in skeletal muscles have been described. Imaging techniques such as Dual Energy X-ray Absorptiometry (DEXA) and Computed Tomography (CT) have revealed atrophy in several paretic side muscles of stroke survivors (English et al., 2010; Scherbakov et al., 2015). In addition to atrophy, increased intramuscular fat has been found in hemiparetic muscles of post-stroke patients (Ryan et al., 2002, Klein et al., 2010, Ryan et al., 2011).
Source: Clinical Neurophysiology - November 9, 2016 Category: Neuroscience Authors: Frank Berenpas, Anne-Marieke Martens, Vivian Weerdesteyn, Alexander C. Geurts, Nens van Alfen Source Type: research

PB 23 Factors predicting global cognitive ability 6month after stroke – preliminary results from the Phys-Stroke trial
Stroke is one of the most frequent causes of chronic and often severe language and motor impairments. Moreover, stroke increases the risk of developing cognitive impairments or even dementia over time (Pendlebury and Rothwell, 2009). Although recent studies investigated predictors of cognitive decline after stroke, several questions remain. In particular, it needs to be clarified whether therapies applied during the rehabilitation phase may reduce or even prevent cognitive decline.
Source: Clinical Neurophysiology - September 8, 2017 Category: Neuroscience Authors: T. Rackoll, K. Prehn, C. N àjera, L. Doppelbauer, A. Flöel Tags: Poster Blitz Source Type: research

IS 27. Brain stimulation in stroke therapy
Non-invasive brain stimulation has shown its potential to modulate brain plasticity and enhance the effects of training in humans (Zimerman et al., Ann Neurol; 2012). Endeavour has been made to utilize brain stimulation in neurological diseases to enhance adaptive processes and prevent potential maladaptive ones. First studies presented evidence that non-invasive brain stimulation might not only transiently improve functions of the paretic hand, but can also modulate processes of learning (Zimerman et al., Stroke; 2012), a basis to achieve longer lasting effects. Based on this enhancement of functional recovery of both, se...
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: F.C. Hummel Tags: Society Proceedings Source Type: research

P 155. Serial anodal tDCS over V1 induces long-term effects on colour discrimination in V4 measured in the unimpaired hemifield of patients with occipital stroke
Conclusion: Long-term modulation in colour perception following serial anodal tDCS may represent evidence of inducible long-term plasticity in distantly connected components of the visual system (V1 and V4) in patients with occipital stroke measured in the unimpaired hemifield. This builds on studies describing the immediate effects of tDCS in the visual system in healthy volunteers. The temporal dynamics of serial anodal tDCS seem to interact with learning processes, and may yield potential support for neuroplastic adaptation processes following cerebral lesions. Future studies should examine the long-term outcomes and dy...
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: R. Dargie, M. Olma, J. Behrens, A. Kraft, K. Irlbacher, M. Fahle, S. Brandt Tags: Society Proceedings Source Type: research

P 240. Improvement of language functions in a chronic non-fluent post-stroke aphasic patient following sequential bilateral non-invasive neuromodulation by theta burst magnetic stimulation
Conclusions: Described sequential bilateral physiologically balanced TMS modulation of activation of the language related areas of both hemispheres may result in considerable and rather fast language benefits in chronic nfA patients. Whether this approach is better than usual unilateral stimulation requires further studies.
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: S. Filipovic, V. Stevanovic, I. Avramovic, M. Jelic, I. Avramovic, A. Jeremic, K. Kacar, S. Milanovic, L. Konstantinovic, J. Vuksanovic Tags: Society Proceedings Source Type: research

IS 27. Brain stimulation in stroke therapy
Non-invasive brain stimulation has shown its potential to modulate brain plasticity and enhance the effects of training in humans (Zimerman et al., Ann Neurol; 2012). Endeavour has been made to utilize brain stimulation in neurological diseases to enhance adaptive processes and prevent potential maladaptive ones. First studies presented evidence that non-invasive brain stimulation might not only transiently improve functions of the paretic hand, but can also modulate processes of learning (Zimerman et al., Stroke; 2012), a basis to achieve longer lasting effects. Based on this enhancement of functional recovery of both, se...
Source: Clinical Neurophysiology - September 19, 2013 Category: Neuroscience Authors: F.C. Hummel Tags: Society Proceedings Source Type: research

P 155. Serial anodal tDCS over V1 induces long-term effects on colour discrimination in V4 measured in the unimpaired hemifield of patients with occipital stroke
Conclusion: Long-term modulation in colour perception following serial anodal tDCS may represent evidence of inducible long-term plasticity in distantly connected components of the visual system (V1 and V4) in patients with occipital stroke measured in the unimpaired hemifield. This builds on studies describing the immediate effects of tDCS in the visual system in healthy volunteers. The temporal dynamics of serial anodal tDCS seem to interact with learning processes, and may yield potential support for neuroplastic adaptation processes following cerebral lesions. Future studies should examine the long-term outcomes and dy...
Source: Clinical Neurophysiology - September 19, 2013 Category: Neuroscience Authors: R. Dargie, M. Olma, J. Behrens, A. Kraft, K. Irlbacher, M. Fahle, S. Brandt Tags: Society Proceedings Source Type: research

P 240. Improvement of language functions in a chronic non-fluent post-stroke aphasic patient following sequential bilateral non-invasive neuromodulation by theta burst magnetic stimulation
Conclusions: Described sequential bilateral physiologically balanced TMS modulation of activation of the language related areas of both hemispheres may result in considerable and rather fast language benefits in chronic nfA patients. Whether this approach is better than usual unilateral stimulation requires further studies.
Source: Clinical Neurophysiology - September 19, 2013 Category: Neuroscience Authors: S. Filipovic, V. Stevanovic, I. Avramovic, M. Jelic, I. Avramovic, A. Jeremic, K. Kacar, S. Milanovic, L. Konstantinovic, J. Vuksanovic Tags: Society Proceedings Source Type: research

56. Effects of deep repetitive transcranial magnetic stimulation (rTMS) on motor function of paretic lower limb in chronic sub-cortical stroke: A pilot study
Repetitive transcranial magnetic stimulation (rTMS) has been recognized as a promising intervention for treatment of stroke patients. The purpose of this double-blind placebo-controlled crossover study was to assess the efficacy of 20Hz rTMS delivered with H-coil on lower limb (LL) motor function in patients with chronic (>6months) subcortical stroke. Nine patients received both real and sham rTMS in a random sequence. rTMS treatments were composed of 11 sessions (administered over 3-weeks) and were separated by a 4-week wash-out period. LL functions were assessed by the Fugl-Meyer LL scale (FM-LL), the 10-meters walking t...
Source: Clinical Neurophysiology - October 21, 2013 Category: Neuroscience Authors: R. Chieffo, S. De Prezzo, E. Houdayer, A. Nuara, L. Straffi, F. Spagnolo, D.Dalla Libera, G.Di Maggio, E. Coppi, L. Ferrari, M. Sessa, M. Comola, A. Zangen, G. Comi, L. Leocani Tags: Society Proceedings Source Type: research

Priming sensorimotor cortex to enhance task-specific training after subcortical stroke
Conclusion: Primary motor cortex iTBS not only modulates M1 corticospinal excitability but also increases M1 receptiveness to sensory input.Significance: Priming with iTBSiM1 may enhance ipsilesional sensorimotor integration and facilitate better quality sensorimotor training after subcortical stroke.
Source: Clinical Neurophysiology - December 23, 2013 Category: Neuroscience Authors: Suzanne J. Ackerley, Cathy M. Stinear, P. Alan Barber, Winston D. Byblow Tags: Neural Plasticity, Functional Adaptation and Recovery Source Type: research

106. Deep repetitive transcranial magnetic stimulation (rTMS) with H-coil coupled with cycling in chronic lower limb dysfuncion after stroke: A randomized, placebo-controlled, crossover study
Repetitive transcranial magnetic stimulation (rTMS) has been recognized as a promising intervention for treatment of post-stroke deficits. We evaluated the feasibility, safety and efficacy of excitatory Hz rTMS with H-coil over the leg motor areas combined with active cycling on paretic lower limb motor function in chronic post-stroke. rTMS was delivered with the H-coil targeting the lower limbs (real or sham for 11 sessions over 3weeks, with cross-over after 4weeks wash-out, in 12 subjects with first stroke more than 6months before.
Source: Clinical Neurophysiology - December 13, 2014 Category: Neuroscience Authors: R. Chieffo, F. Giatsidis, E. Houdayer, M. Fichera, A. Nuara, E. Coppi, L. Ferrari, G. Di Maggio, R. Santangelo, A. Poggi, M. Sessa, M. Comola, A. Zangen, G. Comi, L. Leocani Source Type: research

1. Epileptic seizures in pediatric stroke: Data from the Italian Registry for Childhood Thrombosis
According to data from the Italian Registry for Childhood Thrombosis (R.I.T.I.), in about half cases diagnosis of pediatric stroke occurs after 24h from clinical onset (Baggio et al., SINP2013). The aim of the present study was to evaluate the frequency of seizures at stroke onset and their correlation with time to diagnosis in the pediatric stroke patients in the R.I.T.I. We selected the R.I.T.I. children with first acute arterial (AIS) or venous (CSVT) cerebral infarction occurring between January 2007 and June 2012; we studied prevalence, characteristics and recurrence of epileptic seizures, focusing on diagnostic delay.
Source: Clinical Neurophysiology - December 13, 2014 Category: Neuroscience Authors: L. Baggio, S. Sartori, M. Nosadini, C. Gentilomo, P. Saracco, M. Agostini, B. Bassi, A. Palmieri, A.M. Laverda, P. Simioni, A. Suppiej, per il G.I.R.T.I. (Gruppo Italiano Registro Trombosi Infantili) Source Type: research

ID 297 – Changes in finger tapping-related desynchronization during motor stroke recovery
Complex mechanisms underlying stroke recovery and modulations of associated brain activities are still far to be well elucidated. Here we investigated the potential effects of motor stroke recovery on finger tapping-related (FTR) brain dynamics by using high-power EEG with 128 channels and 2048Hz sampling rate. A follow-up study was carried out on six patients with ischemic stroke. Patients were instructed to perform finger tapping with their right or left index finger at a pace determined by a visual cue.
Source: Clinical Neurophysiology - February 11, 2016 Category: Neuroscience Authors: B. Weiss, J. Körmendi, A. Papp, M. Dombovári, Z. Nagy Source Type: research

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