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Impact of mechanical circulatory support on post-transplant stroke risk
This study assesses if the type of circulatory support device affects stroke risk in this population. The study cohort of 4257 adult patients bridged with mechanical support to cardiac transplant were derived from the UNOS transplant registry data. Risk factors assessed were age, gender, ischemic time, diabetes (recipient), durable mechanical support at listing and mechanical ventilation pre-transplant. Descriptive statistics were used to describe characteristics of the study cohort. Univariate logistic regression was used to test if there is a significant association between stroke event and all the potential risk factors...
Source: The International Journal of Artificial Organs - August 19, 2021 Category: Transplant Surgery Authors: Nandini Nair Shengping Yang Enrique Gongora Source Type: research

Predicting post-LVAD outcome: Is there a role for cognition?
CONCLUSION: Cognitive performance was predictive of post-LVAD risk of stroke and death. Results are consistent with findings from other studies in non-LVAD samples and may reflect early signs of neurologic vulnerability. Further studies are needed to clarify the relationship between cognition and LVAD outcomes in order to optimize patient selection, management, and advanced care planning. PMID: 32907453 [PubMed - as supplied by publisher]
Source: The International Journal of Artificial Organs - September 9, 2020 Category: Transplant Surgery Authors: Pavol MA, Boehme AK, Willey JZ, Festa JR, Lazar RM, Nakagawa S, Casida J, Yuzefpolskaya M, Colombo PC Tags: Int J Artif Organs Source Type: research

Outcomes of systemic anticoagulation with bivalirudin for Impella 5.0
Int J Artif Organs. 2021 Jul 12:3913988211032238. doi: 10.1177/03913988211032238. Online ahead of print.ABSTRACTTemporary mechanical circulatory support (tMCS) devices are used for the management of cardiogenic shock. The Impella 5.0 (Abiomed; Danvers, MA) (IMP5) is a commonly used, surgically implanted, tMCS device that requires systemic anticoagulation and purge solution to avoid pump failure. To avoid heparin-induced thrombocytopenia (HIT) from unfractionated heparin (UFH) use, our program has explored the utility of bivalirudin (BIV) for systemic anticoagulation in IMP5. This single center, retrospective study included...
Source: The International Journal of Artificial Organs - July 12, 2021 Category: Transplant Surgery Authors: Carly Fabrizio Marissa N Levito Ryan Rivosecchi Michael Bashline Brittany Slocum Arman Kilic Catalin Toma Holt Murray Raj Ramanan Jeffrey Fowler Gavin W Hickey Edward T Horn Source Type: research

Direct epicardial assist device using artificial rubber muscle in a swine model of pediatric dilated cardiomyopathy.
CONCLUSIONS: Use of a circumferential direct epicardial assistant device resulted in improvement in hemodynamic data in a dilated cardiomyopathy model. Although there is still a need for improvements in device components, the direct cardiac assist device may be a good alternative to recent heart failure device therapies. PMID: 26659480 [PubMed - as supplied by publisher]
Source: The International Journal of Artificial Organs - December 7, 2015 Category: Transplant Surgery Authors: Saito Y, Suzuki Y, Kondo N, Kowatari R, Daitoku K, Minakawa M, Fukuda I Tags: Int J Artif Organs Source Type: research

Comparison of household income in in-hospital outcomes after implantation of left ventricular assist device
CONCLUSION: In patients undergoing LVAD implantation nationwide, low-income was associated with increased comorbidity burden, younger age, and fewer in-hospital complications and all-cause mortality.PMID:34719291 | DOI:10.1177/03913988211056960
Source: The International Journal of Artificial Organs - November 1, 2021 Category: Transplant Surgery Authors: Bertrand Ebner Morgan Karetnick Jelani Grant Louis Vincent Jennifer Maning Neal Olarte Odunayo Olorunfemi Colombo Rosario Sandra Chaparro Source Type: research

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