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Source: Stroke
Education: Study
Procedure: PET Scan
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Total 111 results found since Jan 2013.
Quantifying Infarct Growth and Secondary Injury Volumes Clinical Sciences
Conclusions—The contributions of IG and AD to lesion expansion can be measured separately over time through the use of image registration. This approach can be used to combine imaging outcome data from computed tomography and MRI.
Source: Stroke - June 25, 2018 Category: Neurology Authors: George W.J. Harston, Davide Carone, Fintan Sheerin, Mark Jenkinson, James Kennedy Tags: Imaging, Ischemic Stroke Original Contributions Source Type: research
Texture Analysis of T1-Weighted and Fluid-Attenuated Inversion Recovery Images Detects Abnormalities That Correlate With Cognitive Decline in Small Vessel Disease Clinical Sciences
Conclusions—TP, which can be obtained from routine clinical images, are abnormal in SVD, and the degree of abnormality correlates with executive dysfunction and global cognition at baseline and decline during 5 years. TP may be useful to assess disease severity in clinically collected data. This needs testing in data clinically acquired across multiple sites.
Source: Stroke - June 25, 2018 Category: Neurology Authors: Daniel J. Tozer, Eva Zeestraten, Andrew J. Lawrence, Thomas R. Barrick, Hugh S. Markus Tags: Imaging, Magnetic Resonance Imaging (MRI), Vascular Disease Original Contributions Source Type: research
Magnetic Resonance Imaging Selection for Endovascular Stroke Therapy Clinical Sciences
Conclusions—Workflow in GOLIATH demonstrates that magnetic resonance imaging selection for endovascular therapy can be accomplished rapidly and within a similar time frame as computed tomography-based selection.Clinical Trial Registration—URL: https://www.clinicaltrials.gov. Unique identifier: NCT02317237.
Source: Stroke - May 25, 2018 Category: Neurology Authors: Claus Z. Simonsen, Albert J. Yoo, Mads Rasmussen, Kristina E. Sorensen, Thabele Leslie–Mazwi, Grethe Andersen, Leif H. Sorensen Tags: Magnetic Resonance Imaging (MRI), Revascularization, Ischemic Stroke Original Contributions Source Type: research
Clinical Utility of Electronic Alberta Stroke Program Early Computed Tomography Score Software in the ENCHANTED Trial Database Clinical Sciences
Background and Purpose—Clinical utility of electronic Alberta Stroke Program Early CT Score (e-ASPECTS), an automated system for quantifying signs of infarction, was evaluated in a large database of thrombolyzed patients with acute ischemic stroke.Methods—All baseline noncontrast computed tomographic scans of patients with anterior circulation acute ischemic stroke who participated in the alteplase dose arm of the randomized controlled trial ENCHANTED (Enhanced Control of Hypertension and Thrombolysis Stroke Study) were reviewed; poor quality and large (>6 mm) slice thickness were excluded. Included scans had e-ASPECTS...
Source: Stroke - May 25, 2018 Category: Neurology Authors: Simon Nagel, Xia Wang, Cheryl Carcel, Thompson Robinson, Richard I. Lindley, John Chalmers, Craig S. Anderson Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research
Time From Imaging to Endovascular Reperfusion Predicts Outcome in Acute Stroke Clinical Sciences
Conclusions—Compared with target mismatch patients, those with the malignant profile experience faster infarct growth and a steeper decline in the odds of functional independence, with longer delays between baseline imaging and reperfusion. However, this does not exclude the possibility of treatment benefit in patients with a malignant profile.
Source: Stroke - March 26, 2018 Category: Neurology Authors: Jenny P. Tsai, Michael Mlynash, Soren Christensen, Stephanie Kemp, Sun Kim, Nishant K. Mishra, Christian Federau, Raul G. Nogueira, Tudor G. Jovin, Thomas G. Devlin, Naveed Akhtar, Dileep R. Yavagal, Roland Bammer, Matus Straka, Gregory Zaharchuk, Michael Tags: Revascularization, Cerebrovascular Procedures, Ischemic Stroke Original Contributions Source Type: research
Association of Progression of Carotid Artery Wall Volume and Recurrent Transient Ischemic Attack or Stroke Clinical Sciences
Conclusions—The annual progression of carotid wall volume is independently associated with recurrent ischemic cerebrovascular events, and this measurement has added value for intraplaque hemorrhage and fibrous cap rupture in predicting future events.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Mingming Lu, Peng Peng, Yuanyuan Cui, Huiyu Qiao, Dongye Li, Jianming Cai, Xihai Zhao Tags: Clinical Studies, Magnetic Resonance Imaging (MRI), Atherosclerosis Original Contributions Source Type: research
Oxidative Stress Biomarkers of Brain Damage Clinical Sciences
Conclusions—Elevated hyperacute plasma F2-isoP concentrations independently predict the occurrence of IG and IG volume in patients with acute ischemic stroke. If validated in future studies, measuring plasma F2-isoP might be helpful in the acute setting to stratify patients with acute ischemic stroke for relative severity of ischemic injury and expected progression.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Svetlana Lorenzano, Natalia S. Rost, Muhib Khan, Hua Li, Fabricio O. Lima, Matthew B. Maas, Rebecca E. Green, Tijy K. Thankachan, Allison J. Dipietro, Ken Arai, Angel T. Som, Loc-Duyen D. Pham, Ona Wu, Gordon J. Harris, Eng H. Lo, Jeffrey B. Blumberg, Pau Tags: Ischemic Stroke Original Contributions Source Type: research
Lacunar Infarcts, but Not Perivascular Spaces, Are Predictors of Cognitive Decline in Cerebral Small-Vessel Disease Clinical Sciences
Conclusions—Although a feature of small-vessel disease, PvS are not a predictor of cognitive decline, in contrast to lacunes. This study highlights the importance of carefully differentiating between lacunes and PvS in studies investigating vascular cognitive impairment.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Philip Benjamin, Sarah Trippier, Andrew J. Lawrence, Christian Lambert, Eva Zeestraten, Owen A. Williams, Bhavini Patel, Robin G. Morris, Thomas R. Barrick, Andrew D. MacKinnon, Hugh S. Markus Tags: Aging, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research
Induced Hypertension for Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage Clinical Sciences
Conclusions—Before this trial, the effectiveness of induced hypertension for DCI in aneurysmal subarachnoid hemorrhage patients was unknown because current literature consists only of uncontrolled case series. The results from our premature halted trial do not add any evidence to support induced hypertension and show that this treatment can lead to serious adverse events.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT01613235.
Source: Stroke - December 22, 2017 Category: Neurology Authors: Celine S. Gathier, Walter M. van den Bergh, Mathieu van der Jagt, Bon H. Verweiȷ, Jan Willem Dankbaar, Marcella C. Muller, Annemarie W. Oldenbeuving, Gabriel J.E. Rinkel, Arȷen J.C. Slooter, for the HIMALAIA Study Group* Tags: Treatment, Quality and Outcomes, Cerebrovascular Disease/Stroke Original Contributions Source Type: research
Prehospital Systolic Blood Pressure Is Related to Intracerebral Hemorrhage Volume on Admission Brief Report
Background and Purpose—Ultra-early blood pressure (BP) management in the prehospital setting could improve the efficacy of this treatment on attenuating intracerebral hemorrhage (ICH) expansion. We aimed to determine the association of prehospital systolic BP (SBP) with ICH volume, ultra-early hematoma growth, and the spot sign on admission.Methods—We conducted a retrospective study of a prospective database of 219 consecutive patients with spontaneous ICH admitted to the emergency department of a tertiary stroke center during a 3-year period. Prehospital SBP and ICH volume, ultra-early hematoma growth (ICH volume/onse...
Source: Stroke - December 22, 2017 Category: Neurology Authors: David Rodriguez–Luna, Noelia Rodriguez–Villatoro, Jesus M. Juega, Sandra Boned, Marian Muchada, Estela Sanȷuan, Jorge Pagola, Marta Rubiera, Marc Ribo, Pilar Coscoȷuela, Carlos A. Molina Tags: High Blood Pressure, Computerized Tomography (CT), Intracranial Hemorrhage Brief Reports Source Type: research
DWI-ASPECTS (Diffusion-Weighted Imaging-Alberta Stroke Program Early Computed Tomography Scores) and DWI-FLAIR (Diffusion-Weighted Imaging-Fluid Attenuated Inversion Recovery) Mismatch in Thrombectomy Candidates Brief Report
Conclusions—Agreement between clinicians assessing DWI-ASPECTS and DWI-FLAIR mismatch may not be sufficient to make repeatable clinical decisions in mechanical thrombectomy. The dichotomization of the DWI-ASPECTS (0–5 versus 0–6 or 0–6 versus 7–10) improved interrater and intrarater agreement, however, its relevance for patients selection for mechanical thrombectomy needs to be validated in a randomized trial.
Source: Stroke - December 22, 2017 Category: Neurology Authors: Robert Fahed, Augustin Lecler, Candice Sabben, Naim Khoury, Celina Ducroux, Vanessa Chalumeau, Daniele Botta, Erwah Kalsoum, William Boisseau, Loic Duron, Dominique Cabral, Patricia Koskas, Azzedine Benaissa, Hasmik Koulakian, Michael Obadia, Benȷa Tags: Magnetic Resonance Imaging (MRI), Ischemic Stroke Brief Reports Source Type: research
Prevalence and Natural History of Superficial Siderosis Clinical Sciences
This study aimed to report the prevalence and natural history of SS in a population-based study.Methods—Brain magnetic resonance imaging scans from the MCSA (Mayo Clinic Study of Aging), a population-based study of residents 50 to 89 years of age in Olmsted County, Minnesota, were reviewed. Participants with imaging consistent with SS were identified from 2011 through 2016. An inverse probability weighting approach was used to convert our observed frequencies to population prevalence of SS. Additional data abstracted included amyloid positron emission tomography, Apolipoprotein E genotype, coexisting cerebral microbleeds...
Source: Stroke - November 27, 2017 Category: Neurology Authors: Michael Pichler, Prashanthi Vemuri, Alejandro A. Rabinstein, Jeremiah Aakre, Kelly D. Flemming, Robert D. Brown Jr, Neeraj Kumar, Kejal Kantarci, Walter Kremers, Michelle M. Mielke, David S. Knopman, Clifford R. Jack Jr, Ronald C. Petersen, Val Lowe, Jona Tags: Magnetic Resonance Imaging (MRI), Cerebrovascular Malformations, Intracranial Hemorrhage Original Contributions Source Type: research
Neuroimaging Correlates of Cerebral Microbleeds Clinical Sciences
Conclusions—CMBs are a common vascular pathology in the elderly. Markers of hypertensive small-vessel disease may contribute to deep CMBs while cerebral amyloid angiopathy may drive development of lobar CMBs.
Source: Stroke - October 23, 2017 Category: Neurology Authors: Jonathan Graff-Radford, Jeannette Simino, Kejal Kantarci, Thomas H. Mosley Jr, Michael E. Griswold, B. Gwen Windham, A. Richey Sharrett, Marilyn S. Albert, Rebecca F. Gottesman, Clifford R. Jack Jr, Prashanthi Vemuri, David S. Knopman Tags: Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Atherosclerosis Original Contributions Source Type: research
Island Sign Clinical Sciences
Conclusions—The island sign is a reliable CT imaging marker that independently predicts hematoma expansion and poor outcome in patients with ICH. The noncontrast CT island sign may serve as a potential marker for therapeutic intervention.
Source: Stroke - October 23, 2017 Category: Neurology Authors: Qi Li, Qing-Jun Liu, Wen-Song Yang, Xing-Chen Wang, Li-Bo Zhao, Xin Xiong, Rui Li, Du Cao, Dan Zhu, Xiao Wei, Peng Xie Tags: Intracranial Hemorrhage Original Contributions Source Type: research
Microbleeds, Cerebral Hemorrhage, and Functional Outcome After Stroke Thrombolysis Clinical Sciences
Background and Purpose—We assessed whether the presence, number, and distribution of cerebral microbleeds (CMBs) on pre-intravenous thrombolysis MRI scans of acute ischemic stroke patients are associated with an increased risk of intracerebral hemorrhage (ICH) or poor functional outcome.Methods—We performed an individual patient data meta-analysis, including prospective and retrospective studies of acute ischemic stroke treated with intravenous tissue-type plasminogen activator. Using multilevel mixed-effects logistic regression, we investigated associations of pre-treatment CMB presence, burden (1, 2–4, ≥5, and>10...
Source: Stroke - July 24, 2017 Category: Neurology Authors: Andreas Charidimou, Guillaume Turc, Catherine Oppenheim, Shenqiang Yan, Jan F. Scheitz, Hebun Erdur, Pascal P. Klinger–Gratz, Marwan El–Koussy, Wakoh Takahashi, Yusuke Moriya, Duncan Wilson, Chelsea S. Kidwell, Jeffrey L. Saver, Asma Sallem, S Tags: Magnetic Resonance Imaging (MRI), Prognosis, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research
