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Specialty: Neurology
Source: Stroke
Education: Study
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Total 1821 results found since Jan 2013.
P-Wave Indices and Risk of Ischemic Stroke Clinical Sciences
Background and Purpose—Atrial cardiomyopathy is associated with an increased risk of ischemic stroke. P-wave terminal force in lead V1, P-wave duration, and maximum P-wave area are electrocardiographic parameters that have been used to assess left atrial abnormalities related to developing atrial fibrillation. The aim of this systematic review and meta-analysis was to examine their values for predicting ischemic stroke risk.Methods—PubMed and EMBASE databases were searched until December 2016 for studies that evaluated the association between P-wave indices and stroke risk. Both fixed- and random-effects models were us...
Source: Stroke - July 24, 2017 Category: Neurology Authors: Jinli He, Gary Tse, Panagiotis Korantzopoulos, Konstantinos P. Letsas, Sadeq Ali-Hasan-Al-Saegh, Hooman Kamel, Guangping Li, Gregory Y.H. Lip, Tong Liu Tags: Risk Factors, Electrocardiology (ECG), Complications, Meta Analysis, Cerebrovascular Disease/Stroke Original Contributions Source Type: research
Workup for Perinatal Stroke Does Not Predict Recurrence Clinical Sciences
Conclusions—Thrombophilia, arteriopathy, or cardioembolic risk factors were not predictive of recurrent events after perinatal stroke. Thrombophilia evaluation in perinatal stroke should only rarely be considered.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Laura L. Lehman, Jeanette Beaute, Kush Kapur, Amy R. Danehy, Miya E. Bernson-Leung, Hayley Malkin, Michael J. Rivkin, Cameron C. Trenor III Tags: Pediatrics, Quality and Outcomes, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research
Microbleeds, Cerebral Hemorrhage, and Functional Outcome After Stroke Thrombolysis Clinical Sciences
Background and Purpose—We assessed whether the presence, number, and distribution of cerebral microbleeds (CMBs) on pre-intravenous thrombolysis MRI scans of acute ischemic stroke patients are associated with an increased risk of intracerebral hemorrhage (ICH) or poor functional outcome.Methods—We performed an individual patient data meta-analysis, including prospective and retrospective studies of acute ischemic stroke treated with intravenous tissue-type plasminogen activator. Using multilevel mixed-effects logistic regression, we investigated associations of pre-treatment CMB presence, burden (1, 2–4, ≥5, and>10...
Source: Stroke - July 24, 2017 Category: Neurology Authors: Andreas Charidimou, Guillaume Turc, Catherine Oppenheim, Shenqiang Yan, Jan F. Scheitz, Hebun Erdur, Pascal P. Klinger–Gratz, Marwan El–Koussy, Wakoh Takahashi, Yusuke Moriya, Duncan Wilson, Chelsea S. Kidwell, Jeffrey L. Saver, Asma Sallem, S Tags: Magnetic Resonance Imaging (MRI), Prognosis, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research
Use of Statins and Outcomes in Intracerebral Hemorrhage Patients Clinical Sciences
Conclusions—Although statin use, especially continued/new use, was associated with improved intracerebral hemorrhage outcomes, this effect may merely reflect the physician’s view of a patient’s prognosis rather than a predictor of survival.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Fazeel M. Siddiqui, Carl D. Langefeld, Charles J. Moomaw, Mary E. Comeau, Padmini Sekar, Jonathan Rosand, Chelsea S. Kidwell, Sharyl Martini, Jennifer L. Osborne, Sonja Stutzman, Christiana Hall, Daniel Woo Tags: Intracranial Hemorrhage Original Contributions Source Type: research
PHASES Score for the Management of Intracranial Aneurysm Clinical Sciences
Conclusions—There is a progression of PHASES score between stable UIA, growing observed UIA, immediately treated UIA, and aSAH groups. PHASES score of ≤3 is associated with a low but not negligible likelihood of aneurysm rupture, and specificity of the classifier is low.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Philippe Biȷlenga, Renato Gondar, Sabine Schilling, Sandrine Morel, Sven Hirsch, Johanna Cuony, Marco–Vincenzo Corniola, Fabienne Perren, Daniel Rufenacht, Karl Schaller Tags: Clinical Studies, Risk Factors, Cerebral Aneurysm Original Contributions Source Type: research
Admission Brain Cortical Volume Clinical Sciences
Conclusions—Smaller cortical volumes in fronto-temporo-insular areas measured 24 to 72 hours post stroke are associated with cognitive vulnerability in the subacute stroke phase.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Sharmila Sagnier, Gwenaelle Catheline, Bixente Dilharreguy, Fanny Munsch, Antoine Bigourdan, Mathilde Poli, Sabrina Debruxelles, Stephane Olindo, Pauline Renou, Francois Rouanet, Vincent Dousset, Thomas Tourdias, Igor Sibon Tags: Magnetic Resonance Imaging (MRI), Cognitive Impairment, Ischemic Stroke Original Contributions Source Type: research
Age-Specific Sex Differences in Magnetic Resonance Imaging-Depicted Carotid Intraplaque Hemorrhage Clinical Sciences
We report age-specific sex differences in the presence of magnetic resonance imaging-depicted carotid IPH.Methods—Patients (n=1115) underwent magnetic resonance imaging for carotid IPH between 2005 and 2014. Low-grade carotid stenosis patients (n=906) without prior endarterectomy were eligible for this cross-sectional study.Results—Of the 906 patients included (mean age±SD in years, 66.98±15.15), 63 (6.95%) had carotid IPH. In men and women, carotid IPH was present in 11.43% (48 of 420) and 3.09% (15 of 486), respectively (P
Source: Stroke - July 24, 2017 Category: Neurology Authors: Navneet Singh, Alan R. Moody, Bowen Zhang, Isabella Kaminski, Kush Kapur, Stephanie Chiu, Pascal N. Tyrrell Tags: Pathophysiology, Vascular Biology, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Atherosclerosis Original Contributions Source Type: research
Effectiveness and Safety of Apixaban, Dabigatran, and Rivaroxaban Versus Warfarin in Patients With Nonvalvular Atrial Fibrillation and Previous Stroke or Transient Ischemic Attack Clinical Sciences
Conclusions—Results from our study of the 3 NOACs versus warfarin in nonvalvular atrial fibrillation patients with a previous history of stroke/transient ischemic attack are relatively consistent with their respective phase III trials and previous stroke/transient ischemic attack subgroup analyses. All NOACs seemed no worse than warfarin in respect to ischemic stroke, ICH, or major bleeding risk.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Craig I. Coleman, W. Frank Peacock, Thomas J. Bunz, Mark J. Alberts Tags: Arrhythmias, Quality and Outcomes, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research
Challenges in the Medical Management of Symptomatic Intracranial Stenosis in an Urban Setting Clinical Sciences
Background and Purpose—Since the SAMMPRIS trial (Stenting and Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis), aggressive medical management (AMM), which includes dual antiplatelet therapy (DAPT) and high-dose statin (HDS) therapy, is recommended for patients with symptomatic intracranial atherosclerotic disease. However, limited data on the real-world application of this regimen exist. We hypothesized that recurrent stroke risk among patients treated with AMM is similar to the medical arm of the SAMMPRIS cohort.Methods—Using a prospective registry, we identified all patients adm...
Source: Stroke - July 24, 2017 Category: Neurology Authors: Rajbeer S. Sangha, Andrew M. Naidech, Carlos Corado, Sameer A. Ansari, Shyam Prabhakaran Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke, Stenosis, Vascular Disease Original Contributions Source Type: research
Acute Occlusions of Dual-Layer Carotid Stents After Endovascular Emergency Treatment of Tandem Lesions Clinical Sciences
Conclusions—The recently introduced dual-layer stents have a higher risk of acute occlusion compared with single-layer stents in the treatment of acute stroke.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Umut Yilmaz, Heiko Korner, Ruben Muhl–Benninghaus, Andreas Simgen, Catherine Kraus, Silke Walter, Stefanie Behnke, Klaus Fassbender, Wolfgang Reith, Marcus M. Unger Tags: Revascularization, Stent, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research
In-Patient Code Stroke Clinical Sciences
Conclusions—Our study reveals the efficacy of an inpatient code stroke algorithm and educational intervention directed at nurses and allied health personnel to optimize the prompt management of inpatient strokes. Prompt assessment may lead to faster stroke interventions, which are associated with better outcomes.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Charles D. Kassardjian, Jacqueline D. Willems, Krystyna Skrabka, Rosane Nisenbaum, Judith Barnaby, Pawel Kostyrko, Daniel Selchen, Gustavo Saposnik Tags: Quality and Outcomes, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research
Optimal Transport Destination for Ischemic Stroke Patients With Unknown Vessel Status Clinical Sciences
Conclusions—Use of RACE cutoff scores that take into account transport times to triage AIS patients to the nearest appropriate hospital may lead to improved outcomes. Further studies should examine the feasibility of translation into clinical practice.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Eckhard Schlemm, Martin Ebinger, Christian H. Nolte, Matthias Endres, Ludwig Schlemm Tags: Revascularization, Health Services, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research
Disparities and Trends in Door-to-Needle Time Clinical Sciences
Conclusions—In the FL-PR CReSD, achievement of DTNT ≤60 and DTNT ≤45 remains low. Compared with Whites, Blacks less likely receive tPA treatment within 45 minutes during off hours. Treatment within 60 and 45 minutes is lower in women compared with men and lowest in West Central Florida compared with other Florida regions and Puerto Rico. Further research is needed to identify reasons for delayed thrombolytic treatment in women and Blacks and factors contributing to regional disparities in DTNT.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Sofia A. Oluwole, Kefeng Wang, Chuanhui Dong, Maria A. Ciliberti-Vargas, Carolina M. Gutierrez, Li Yi, Jose G. Romano, Enmanuel Perez, Brittany Ann Tyson, Maranatha Ayodele, Negar Asdaghi, Hannah Gardener, David Z. Rose, Enid J. Garcia, Juan Carlos Zevall Tags: Health Services, Quality and Outcomes, Ischemic Stroke Original Contributions Source Type: research
Secondary Versus Primary Stroke Prevention in Atrial Fibrillation: Insights From the Darlington Atrial Fibrillation Registry Clinical Sciences
The objective of this study is to compare clinical outcomes of AF patients with versus without previous stroke in relation to guideline-adherent antithrombotic treatment in a contemporary primary care population.Methods—Community cohort of 105 000 patients from 11 general practices in Darlington, England, was used to assess AF stroke prevention strategies against 2014 National Institute for Health and Care Excellence guidelines.Results—Overall, 2259 (2.15%) patients with AF were identified, of which 18.9% constituted a secondary prevention cohort. For secondary prevention, antithrombotic treatment was guideline adher...
Source: Stroke - July 24, 2017 Category: Neurology Authors: Michał Mazurek, Eduard Shantsila, Deirdre A. Lane, Andreas Wolff, Marco Proietti, Gregory Y.H. Lip Tags: Catheter Ablation and Implantable Cardioverter-Defibrillator, Secondary Prevention, Mortality/Survival, Statements and Guidelines, Ischemic Stroke Original Contributions Source Type: research
Ischemic Stroke Clinical Sciences
Conclusions—Histological thrombus features vary significantly according to the underlying cause and may help to differentiate between cardioembolic and noncardioembolic stroke. In addition, our study supports the hypothesis that most cryptogenic strokes have a cardioembolic cause.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Peter B. Sporns, Uta Hanning, Wolfram Schwindt, Aglae Velasco, Jens Minnerup, Tarek Zoubi, Walter Heindel, Astrid Jeibmann, Thomas Ulrich Niederstadt Tags: Angiography, Revascularization, Cerebrovascular Disease/Stroke, Ischemic Stroke, Embolism Original Contributions Source Type: research
