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Cross-Talk Between Key Players in Patients with COVID-19 and Ischemic Stroke: A  Review on Neurobiological Insight of the Pandemic
AbstractThe global pandemic of novel coronavirus disease 2019 (COVID-19) has taken the entire human race by surprise and led to an unprecedented number of mortalities worldwide so far. Current clinical studies have interpreted that angiotensin-converting enzyme 2 (ACE2) is the host receptor for severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2). In addition, ACE2 is the major component of the renin-angiotensin system. ACE2 deteriorates angiotensin II, a peptide that is responsible for the promotion of stroke. The downregulation of ACE2 further activates an immunological cascade. Thus, researchers need to explore ...
Source: Molecular Neurobiology - October 7, 2020 Category: Neurology Source Type: research