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Source: The American Journal of Cardiology
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Total 366 results found since Jan 2013.

Relation between Cancer and Atrial Fibrillation (from The REasons for Geographic And Racial Differences in Stroke Study)
Atrial fibrillation (AF) is common in patients with life threatening cancer and those undergoing active cancer treatment. However, data from persons with a history of non-life threatening cancer and those who do not require active cancer treatment are lacking. A total of 15,428 (mean age: 66 ± 8.9 years; 47% women; 45% blacks) participants from the REasons for Geographic And Racial Differences in Stroke (REGARDS) with baseline data on prior cancer diagnosis and AF were included. Participants with life threatening cancer and active cancer treatment within 2 years of study enrollment were excluded.
Source: The American Journal of Cardiology - January 31, 2015 Category: Cardiology Authors: Wesley T. O’Neal, Susan G. Lakoski, Waqas Qureshi, Suzanne E. Judd, George Howard, Virginia Howard, Mary Cushman, Elsayed Z. Soliman Source Type: research

Meta-Analysis of the Prognostic Impact of Stroke Volume, Gradient and Ejection Fraction Following Transcatheter Aortic Valve Implantation
The prognostic implications of several baseline pre-procedural variables in patients with severe native valve aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI) are unclear. The goal of this study was to determine the impact of reduced stroke volume index (SVI), low gradient (LG) and reduced ejection fraction (EF) on all-cause mortality. We searched MEDLINE, CENTRAL, EMBASE, Web of Science, and Scopus through 10/13/2014. We evaluated the association between low SVI (
Source: The American Journal of Cardiology - June 25, 2015 Category: Cardiology Authors: Mackram F. Eleid, Kashish Goel, M. Hassan Murad, Patricia J. Erwin, Rakesh M. Suri, Kevin L. Greason, Rick A. Nishimura, Charanjit S. Rihal, David R. Holmes Source Type: research

Meta-analysis of the Prognostic Impact of Stroke Volume, Gradient, and Ejection Fraction After Transcatheter Aortic Valve Implantation
The prognostic implications of several baseline preprocedural variables in patients with severe native valve aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI) are unclear. The goal of this study was to determine the impact of reduced stroke volume index (SVI), low gradient (LG), and reduced ejection fraction (EF) on all-cause mortality. We searched MEDLINE, CENTRAL, EMBASE, Web of Science, and Scopus through October 13, 2014. We evaluated the association between low SVI (
Source: The American Journal of Cardiology - June 25, 2015 Category: Cardiology Authors: Mackram F. Eleid, Kashish Goel, M. Hassan Murad, Patricia J. Erwin, Rakesh M. Suri, Kevin L. Greason, Rick A. Nishimura, Charanjit S. Rihal, David R. Holmes Tags: Review Source Type: research

Effect of Falls on Frequency of Atrial Fibrillation and Mortality Risk (From the REasons for Geographic And Racial Differences in Stroke REGARDS Study)
It is unclear if persons who have atrial fibrillation (AF) have a higher fall risk compared with those in the general population and if falls increase mortality beyond that observed in AF. A total of 24,117 (mean age=65±9.3; 55% female; 38% black) participants from the REasons for Geographic And Racial Differences in Stroke (REGARDS) study were included. AF was identified from baseline electrocardiogram data and by self-reported history. Falls were considered present if participants reported 2 or more falls within the year prior to the baseline examination.
Source: The American Journal of Cardiology - July 28, 2015 Category: Cardiology Authors: Wesley T. O’Neal, Waqas T. Qureshi, Suzanne E. Judd, C. Barrett Bowling, Virginia J. Howard, George Howard, Elsayed Z. Soliman Source Type: research

Impact Of Testosterone Replacement Therapy On Myocardial Infarction, Stroke, And Death In Men With Low Testosterone Concentrations In An Integrated Healthcare System
The aim of this study was to assess the effect of testosterone replacement therapy (TRT) on cardiovascular (CV) outcomes. Males (January 1, 1996-December 31, 2011) with a low initial total testosterone concentration, a subsequent testosterone level, and>3 years of follow-up were studied. Levels were correlated with testosterone supplement use. The primary outcome was major adverse cardiovascular events (MACE), defined as a composite of death, nonfatal myocardial infarction and stroke at 3 years.
Source: The American Journal of Cardiology - December 13, 2015 Category: Cardiology Authors: Jeffrey L. Anderson, Heidi T. May, Donald L. Lappé, Tami Bair, Viet Le, John F. Carlquist, Joseph B. Muhlestein Source Type: research

Meta-Analysis of Anticoagulation Use, Stroke, Thromboembolism, Bleeding and Mortality in Patients with Atrial Fibrillation on Dialysis
Atrial fibrillation (AF) is common in patients on dialysis. While randomized trials of anticoagulation for AF have demonstrated striking reductions in stroke, these trials did not recruit dialysis patients. We thus undertook this systematic review and meta-analysis of observational studies. Electronic databases were searched for studies including AF patients on dialysis that reported observational associations of anticoagulation use. Twenty-one studies involving 530,031 individuals and 31,611 AF patients on dialysis were identified.
Source: The American Journal of Cardiology - April 12, 2016 Category: Cardiology Authors: Christopher X. Wong, Ayodele Odutayo, Connor A. Emdin, Ned J. Kinnear, Michelle T. Sun Source Type: research

Influence of Left Ventricular Stroke Volume on Incident Heart Failure in a Population with Preserved Ejection Fraction (From the Strong Heart Study)
At a given level of left ventricular (LV) systolic function, LV pump performance (assessed by stroke index [SVi]) may differ, depending on LV size. We evaluated whether low SVi may be considered a marker of risk for incident congestive heart failure (HF), independent of LV geometry and systolic function, assessed by ejection fraction (EF) or midwall fractional shortening (MFS), in a large population-based sample with normal EF. Clinical and echocardiographic data from the second Strong Heart Study (SHS) exam, including 2,885 American Indians (59 ±8 years; 63% women) with normal EF (EF≥51% in men and EF≥55% in women) a...
Source: The American Journal of Cardiology - January 4, 2017 Category: Cardiology Authors: Marina De Marco, Eva Gerdts, Costantino Mancusi, Mary J. Roman, Mai Tone L ønnebakken, Elisa T. Lee, Barbara V. Howard, Richard B. Devereux, Giovanni de Simone Source Type: research

Usefulness of the MrWALLETS Scoring System to Predict First Diagnosed Atrial Fibrillation in Ischemic Stroke Patients
In this study we searched for echocardiographic parameters associated with first diagnosed AF, to form a scoring system for the identification of AF patients. We examined 571 ischemic stroke patients (72.7 ±13.5 years, 50.6% women), subdivided into 4 groups: documented cause without AF, first diagnosed AF, known paroxysmal AF, and permanent AF. All patients underwent transthoracic echocardiography, brain CT scan, carotid/vertebral ultrasound, and continuous ECG monitoring.
Source: The American Journal of Cardiology - January 4, 2017 Category: Cardiology Authors: Antonio Muscari, Andrea Bonfiglioli, Luca Faccioli, Marco Ghinelli, Donatella Magalotti, Francesco Manzetto, Anna Pontarin, Giovanni M. Puddu, Luca Spinardi, Eleonora Tubertini, Marco Zoli Source Type: research

Usefulness of the MrWALLETS Scoring System to Predict First Diagnosed Atrial Fibrillation in Patients With Ischemic Stroke
In this study, we searched for echocardiographic parameters associated with first diagnosed AF, to form a scoring system for the identification of patients with AF. We examined 571 patients with ischemic stroke (72.7  ± 13.5 years, 50.6% women), subdivided into 4 groups: documented cause without AF, first diagnosed AF, known paroxysmal AF, and permanent AF. All patients underwent transthoracic echocardiography, brain computed tomography scan, carotid/vertebral ultrasound, and continuous electrocardiographic monitoring.
Source: The American Journal of Cardiology - January 4, 2017 Category: Cardiology Authors: Antonio Muscari, Andrea Bonfiglioli, Luca Faccioli, Marco Ghinelli, Donatella Magalotti, Francesco Manzetto, Anna Pontarin, Giovanni M. Puddu, Luca Spinardi, Eleonora Tubertini, Marco Zoli Tags: Arrhythmias and Conduction Disturbances Source Type: research

Changing Trends of Atherosclerotic Risk Factors Among Patients with Acute Myocardial Infarction and Acute Ischemic Stroke
We aimed to evaluate the secular trends in demographics, risk factors as well as clinical characteristics of patients presenting with acute myocardial infarction (AMI) or acute ischemic stroke (AIS), using a large nationally representative dataset of in-hospital admissions. We used the 2003-2013 Nationwide Inpatient Sample. All admissions with primary diagnosis of AMI or AIS were included. Across 2003-2013, a total of 1,360,660 patients with AMI and 937,425 patients with AIS were included in the study.
Source: The American Journal of Cardiology - February 27, 2017 Category: Cardiology Authors: Shikhar Agarwal, Karan Sud, Badal Thakkar, Venu Menon, Wael A. Jaber, Samir R. Kapadia Source Type: research

Effect of Atrial Fibrillation on Mortality, Stroke Risk, and Quality of Life Scores in Patients with Heart Failure (From the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation ORBIT-AF)
This study aimed to determine the impact of heart failure (HF) on clinical outcomes in patients with atrial fibrillation (AF). We analyzed data from ORBIT-AF, a national registry of 10,135 AF patients to determine associations between HF as well as left ventricular ejection fraction (LVEF) and outcomes, including stroke, mortality, and hospitalization using Cox multivariable modeling.
Source: The American Journal of Cardiology - March 14, 2017 Category: Cardiology Authors: Tharian S. Cherian, Peter Shrader, Gregg C. Fonarow, Larry A. Allen, Jonathan P. Piccini, Eric D. Peterson, Laine Thomas, Peter R. Kowey, Bernard J. Gersh, Kenneth W. Mahaffey Source Type: research

Relation Between Estimated Cardiorespiratory Fitness and Atrial Fibrillation (From the REasons for Geographic and Racial Differences in Stroke Study)
This study included 10,126 participants (54.5% women, 35% African American, mean age 63.2 years) from the REasons for Geographic And Racial Differences in Stroke (REGARDS) study who were free of AF at baseline. Baseline (2003-2007) e-CRF was determined using a previously validated non-exercise algorithm.
Source: The American Journal of Cardiology - March 14, 2017 Category: Cardiology Authors: Abhishek Bose, Wesley T. O ’Neal, Aleena Bennett, Suzanne E. Judd, Waqas T. Qureshi, Xuemei Sui, Virginia J. Howard, George Howard, Elsayed Z. Soliman Source Type: research

Effect of Atrial Fibrillation on Mortality, Stroke Risk, and Quality-of-Life Scores in Patients With Heart Failure (from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation ORBIT-AF)
This study aimed to determine the impact of HF on clinical outcomes in patients with AF. We analyzed data from Outcomes Registry for Better Informed Treatment of Atrial Fibrillation, a national registry of 10,135 patients with AF to determine associations between HF and left ventricular ejection fraction (LVEF) and outcomes, including stroke, mortality, and hospitalization using Cox multivariable modeling.
Source: The American Journal of Cardiology - March 15, 2017 Category: Cardiology Authors: Tharian S. Cherian, Peter Shrader, Gregg C. Fonarow, Larry A. Allen, Jonathan P. Piccini, Eric D. Peterson, Laine Thomas, Peter R. Kowey, Bernard J. Gersh, Kenneth W. Mahaffey Tags: Arrhythmias and Conduction Disturbances Source Type: research

Rivaroxaban for Stroke Prevention in Patients with Non-Valvular Atrial Fibrillation and Active Cancer.
Rivaroxaban is broadly used for the primary prevention of stroke and systemic embolism in the general population with non-valvular atrial fibrillation (AF). However, there is little published evidence on the safety and efficacy of rivaroxaban for AF in patients with active cancer. The aim of this study was to assess the safety and efficacy of rivaroxaban in patients with active cancer and AF. Use of rivaroxaban in cancer patients at Memorial Sloan Kettering Cancer Center (MSKCC) is monitored in the setting of a Quality Assessment Initiative.
Source: The American Journal of Cardiology - April 26, 2017 Category: Cardiology Authors: Eva S. Laube, Anthony Yu, Dipti Gupta, Yimei Miao, Patrick Samedy, Jonathan Wills, Stephen Harnicar, Gerald A. Soff, Simon Mantha Source Type: research

Rivaroxaban for Stroke Prevention in Patients With Nonvalvular Atrial Fibrillation and Active Cancer
Rivaroxaban is broadly used for the primary prevention of stroke and systemic embolism in the general population with nonvalvular atrial fibrillation (AF). However, there is little published evidence on the safety and efficacy of rivaroxaban for AF in patients with active cancer. The aim of this study was to assess the safety and efficacy of rivaroxaban in patients with active cancer and AF. The use of rivaroxaban in patients with cancer at the Memorial Sloan Kettering Cancer Center is monitored in the setting of a Quality Assessment Initiative.
Source: The American Journal of Cardiology - April 26, 2017 Category: Cardiology Authors: Eva S. Laube, Anthony Yu, Dipti Gupta, Yimei Miao, Patrick Samedy, Jonathan Wills, Stephen Harnicar, Gerald A. Soff, Simon Mantha Tags: Arrhythmias and Conduction Disturbances Source Type: research