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Source: The American Journal of Cardiology
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Total 366 results found since Jan 2013.
Relation of Atrial Fibrillation to Cognitive Decline (from the REasons for Geographic and Racial Differences in Stroke REGARDS Study)
The association of atrial fibrillation (AF) with cognitive function remains unclear, especially among racially/geographically diverse populations. This analysis included 25,980 black and white adults, aged 48+, from the national REasons for Geographic and Racial Differences in Stroke (REGARDS) cohort, free from cognitive impairment and stroke at baseline. Baseline AF was identified by self-reported medical history or electrocardiogram (ECG). Cognitive testing was conducted yearly with the Six Item Screener (SIS) to define impairment and at 2-year intervals to assess decline on: animal naming and letter fluency, Montreal Co...
Source: The American Journal of Cardiology - March 5, 2021 Category: Cardiology Authors: Margie J. Bailey, Elsayed Z. Soliman, Leslie A. McClure, George Howard, Virginia J. Howard, Suzanne E. Judd, Fred Unverzagt, Virginia Wadley, Bonnie C. Sachs, Timothy Hughes Source Type: research
Trends in Cerebral Embolic Protection Device Use and Association With Stroke Following Transcatheter Aortic Valve Implantation
Stroke remains a serious complication of transcatheter aortic valve implantation (TAVI). Prior studies examining the association between cerebral embolic protection device (CEPD) use and stroke following TAVI have produced conflicting results. We used the Nationwide Readmissions Databases to identify all percutaneous (non-transapical) TAVIs performed in the US from July, 2017 to December, 2018. Overlap propensity score weighted logistic regression models were used to determine the association between CEPD use and outcomes.
Source: The American Journal of Cardiology - June 17, 2021 Category: Cardiology Authors: Dhaval Kolte, Sahil Khera, Salik Nazir, Neel M. Butala, Deepak L. Bhatt, Sammy Elmariah Source Type: research
The CHA2DS2-VASc Score for Risk Stratification of Stroke in Heart Failure With-vs-Without Atrial Fibrillation
A recent study suggested that the CHA2DS2-VASc score can risk stratify heart failure (HF) patients without atrial fibrillation (AF) for stroke. We performed a retrospective analysis using the national Veteran Affairs database to externally validate the findings. Crude incidence rates of end points were calculated. A Cox proportional model was used to study the association between the CHA2DS2-VASc score and outcomes. In HF patients with AF (n = 17,481) and without AF (n = 36,935), the 1 year incidence rate for ischemic stroke, thromboembolism, thromboembolism (without MI), and death were 2.7 and 2.0%; 10.3 and 7.9%; 4....
Source: The American Journal of Cardiology - July 14, 2021 Category: Cardiology Authors: George R. Marzouka, Harold Rivner, Vijay Mehta, Juan Lopez, Igor Vaz, Fei Tang, Hemant Ishwaran, Jeffrey J. Goldberger Source Type: research
Effect of Duration of Anticoagulation in the Incidence of Stroke in Patients With Left-Ventricular Thrombus
The optimal duration of anticoagulation in patients with left-ventricular thrombus (LVT) is unclear. In the present study, we aimed to analyze the effect of treatment duration ( ≤12 months [short-term anticoagulation, (STA)] versus>12 months [long-term anticoagulation, (LTA)]) in the incidence of stroke and other secondary outcomes (acute myocardial infarction, bleeding, and mortality). Multivariate Cox regression was used to determine the association between treatment duration and stroke, adjusted for baseline embolic risk.
Source: The American Journal of Cardiology - October 12, 2022 Category: Cardiology Authors: Álvaro Lorente-Ros, Gonzalo L. Alonso-Salinas, Juan M. Monteagudo Ruiz, María Abellás-Sequeiros, José M. Vieítez-Florez, Diego Sánchez Vega, Jesús Álvarez-Garcia, Marcelo Sanmartín-Fernández, Marta Lorente-Ros, Susana del Prado Díaz, Covadonga Source Type: research
Advanced Echocardiography With Left Atrial Strain and Indexed Left Atrial Three-Dimensional Volume for Predicting Underlying Atrial Fibrillation After Cryptogenic Stroke
Cryptogenic stroke (CS) represents 1/3 of ischemic strokes. Atrial fibrillation (AF) can be detected in up to 30% of CS. Therefore, there is a clinical need for predicting AF to guide the optimal secondary prevention strategy. The evidence about the role of advanced echocardiography, including left atrial 3-dimensional (3D) index volume and left atrial strain (LAS) techniques, to predict underlying AF in this setting is lacking. From April 2019 to November 2021, 78 consecutive patients with ischemic stroke or transient ischemic attack with ABCD2 scale ≥4 of unknown etiology were prospectively recruited.
Source: The American Journal of Cardiology - October 25, 2022 Category: Cardiology Authors: Alberto Vera, Alberto Cecconi, Álvaro Ximénez-Carrillo, Carmen Ramos, Pablo Martínez-Vives, Beatriz Lopez-Melgar, Ancor Sanz-García, Guillermo Ortega, Clara Aguirre, José Vivancos, Luis Jesús Jiménez-Borreguero, Fernando Alfonso, DECRYTORING Study Source Type: research
Effect of Anticoagulation Duration on Stroke Incidence in Asian Patients With Left Ventricular Thrombus
Left ventricular thrombus (LVT) occurs in acute myocardial infarction (AMI) and in ischemic and nonischemic cardiomyopathies.1,2 LVT may result in embolic stroke.3 We read with interest the study by Lorente-Ros et al4 published in the American Journal of Cardiology. That study, conducted in a Spanish cohort, found that prolonged anticoagulation>12 months for LVT was associated with lower stroke risk. We aimed to study the generalizability of these results in an Asian population because the original article was a single-center study with limited representation.
Source: The American Journal of Cardiology - January 24, 2023 Category: Cardiology Authors: Fang Qin Goh, Aloysius S.T. Leow, Jamie S.Y. Ho, Benjamin Y.Q. Tan, Leonard L.L. Yeo, Ching-Hui Sia Source Type: research
Atrial Myopathy and Ischemic Stroke in Heart Failure With Preserved Ejection Fraction
We examined the hypothesis that atrial myopathy may be associated with ischemic stroke in patients with heart failure with preserved ejection fraction. This is an exploratory, post hoc analysis of the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT) trial. Patients with sinus rhythm documented at baseline electrocardiogram and without known AF were included in this analysis.
Source: The American Journal of Cardiology - July 27, 2023 Category: Cardiology Authors: Kassem Farhat, Khaled Elkholey, Zain Ul Abideen Asad, Stavros Stavrakis Source Type: research
Troponin T in Acute Ischemic Stroke
In conclusion, elevated cTnT can be frequently detected in patients with AIS. To reliably identify patients with current acute myocardial impairment, more in-depth clinical investigation is needed.
Source: The American Journal of Cardiology - April 8, 2013 Category: Cardiology Authors: Michal Král, Daniel Šaňák, Tomáš Veverka, Martin Hutyra, David Vindiš, Anna Kunčarová, Andrea Bártková, Tomáš Dorňák, Marija Švábová, Veronika Kubíčková, Jana Zapletalová, Roman Herzig, David Školoudík Tags: Miscellaneous Source Type: research
Effect of Sustaining Lifestyle Modifications (Nonsmoking, Weight Reduction, Physical Activity, and Mediterranean Diet) After Healing of Myocardial Infarction, Percutaneous Intervention, or Coronary Bypass (from the REasons for Geographic and Racial Differences in Stroke Study)
Guidelines recommend lifestyle modification for patients with coronary heart disease (CHD). Few data demonstrate which lifestyle modifications, if sustained, reduce recurrent CHD and mortality risk in cardiac patients after the postacute rehabilitation phase. We determined the association between ideal lifestyle factors and recurrent CHD and all-cause mortality in REasons for Geographic and Racial Differences in Stroke study participants with CHD (n = 4,174). Ideal lifestyle factors (physical activity ≥4 times/week, nonsmoking, highest quartile of Mediterranean diet score, and waist circumference
Source: The American Journal of Cardiology - April 3, 2014 Category: Cardiology Authors: John N. Booth, Emily B. Levitan, Todd M. Brown, Michael E. Farkouh, Monika M. Safford, Paul Muntner Tags: Coronary Artery Disease Source Type: research
Relation Between Stroke Volume Index to Risk of Death in Patients With Low-Gradient Severe Aortic Stenosis and Preserved Left Ventricular Function
The aim of the present study was to evaluate whether assessment of stroke volume index (SVI) can be used to improve risk stratification among patients with low-gradient severe aortic stenosis and preserved ejection fraction (EF). Study population comprised 409 patients with aortic valve area ≤1.00 cm2, mean gradient
Source: The American Journal of Cardiology - May 19, 2014 Category: Cardiology Authors: Elad Maor, Roy Beigel, Avishay Grupper, Rafael Kuperstein, Ilan Hai, Diego Medvedofsky, Olga Perelstein, Israel Mazin, Asaf Ziv, Ilan Goldenberg, Micha S. Feinberg, Sagit Ben Zekry Tags: Valvular Heart Disease Source Type: research
Cost Effectiveness of Percutaneous Closure Versus Medical Therapy for Cryptogenic Stroke in Patients With a Patent Foramen Ovale
In patients with patent foramen ovales (PFOs) and cryptogenic stroke, observational studies have demonstrated reductions in recurrent neurologic events with transcatheter PFO closure compared with medical therapy. Randomized controlled trials and meta-analyses have shown a trend toward benefit with device closure. The cost-effectiveness of PFO closure has not been described. Therefore, a detailed cost analysis was performed using pooled weighted outcome and complication rates from published randomized controlled trials, Medicare cost tables, and wholesale medication prices.
Source: The American Journal of Cardiology - September 4, 2014 Category: Cardiology Authors: Christopher A. Pickett, Todd C. Villines, Michael A. Ferguson, Edward A. Hulten Tags: Miscellaneous Source Type: research
Impact of Transesophageal Echocardiography on Management in Patients with Suspected Cardioembolic Stroke
Transesophageal echocardiography (TEE) is frequently performed in patients with acute ischemic cerebrovascular events to exclude a cardioembolic source. We aimed to determine the clinical impact of transesophageal echocardiography on clinical management. This is a retrospective single center study of 1458 consecutive patients hospitalized with acute ischemic stroke or transient ischemic attack who underwent TEE for evaluation of a suspected cardioembolic etiology. Significant TEE findings were determined for each patient as recorded on the TEE report.
Source: The American Journal of Cardiology - September 25, 2014 Category: Cardiology Authors: Yevgeniy Khariton, John A. House, Lynn Comer, Tina Coggins, Anthony Magalski, David G. Skolnick, Thomas H. Good, Michael L. Main Source Type: research
Atrial Fibrillation, Stroke and Mortality Rates Following Transcatheter Aortic Valve Implantation
Transcatheter aortic valve implantation (TAVI) is considered a suitable treatment for patients with severe symptomatic aortic stenosis (AS) and high operative risk. Our aim was to evaluate the effect of pre-procedural and new-onset atrial fibrillation (NOAF) on mortality and stroke in patients undergoing TAVI. We performed a single center study of 380 consecutive patients enrolled to a TAVI registry. NOAF was defined as post-procedural atrial fibrillation (AF) occurring within 30 days following the procedure.
Source: The American Journal of Cardiology - September 25, 2014 Category: Cardiology Authors: Lior Yankelson, Arie Steinvil, Liron Gershovitz, Eran Leshem-Rubinow, Ariel Furer, Sami Viskin, Gad Keren, Shmuel Banai, Ariel Finkelstein Source Type: research
Impact of Transesophageal Echocardiography on Management in Patients With Suspected Cardioembolic Stroke
Transesophageal echocardiography (TEE) is frequently performed in patients with acute ischemic cerebrovascular events to exclude a cardioembolic source. We aimed to determine the clinical impact of TEE on management. This is a retrospective single-center study of 1,458 consecutive patients hospitalized with acute ischemic stroke or transient ischemic attack who underwent TEE for evaluation of a suspected cardioembolic cause. Significant TEE findings were determined for each patient as recorded on the TEE report.
Source: The American Journal of Cardiology - September 25, 2014 Category: Cardiology Authors: Yevgeniy Khariton, John A. House, Lynn Comer, Tina R. Coggins, Anthony Magalski, David G. Skolnick, Thomas H. Good, Michael L. Main Tags: Miscellaneous Source Type: research
Atrial Fibrillation, Stroke, and Mortality Rates After Transcatheter Aortic Valve Implantation
Transcatheter aortic valve implantation (TAVI) is considered a suitable treatment for patients with severe symptomatic aortic stenosis and high operative risk. Our aim was to evaluate the effect of preprocedural and new-onset atrial fibrillation (NOAF) on mortality and stroke in patients who underwent TAVI. We performed a single-center study of 380 consecutive patients enrolled to a TAVI registry. NOAF was defined as postprocedural atrial fibrillation (AF) occurring within 30 days after the procedure.
Source: The American Journal of Cardiology - September 25, 2014 Category: Cardiology Authors: Lior Yankelson, Arie Steinvil, Liron Gershovitz, Eran Leshem-Rubinow, Ariel Furer, Sami Viskin, Gad Keren, Shmuel Banai, Ariel Finkelstein Tags: Valvular Heart Disease Source Type: research
