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Source: The American Journal of Cardiology
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Total 366 results found since Jan 2013.
Usefulness of B-type Natriuretic Peptides to Predict Cardiovascular Events in Women (From the Women’s Health Study)
Natriuretic peptides are positively associated with incident cardiovascular disease (CVD), but data in women, particularly with regard to improvements in risk prediction, are sparse. We measured the N-terminal prohormone form of B-type natriuretic peptide (NT-proBNP) in 480 cases of incident CVD (myocardial infarction, stroke, and cardiovascular death) and a reference subcohort of 564 women from the Women’s Health Study who were followed for a median (IQR) of 11.5 (7.3-13.4) years. Median (IQR) NT-proBNP concentrations were higher in women who developed CVD [81 ng/L (50-147)] than those who did not [64 ng/L (38-117); P
Source: The American Journal of Cardiology - May 21, 2015 Category: Cardiology Authors: Brendan M. Everett, Paul M. Ridker, Nancy R. Cook, Aruna D. Pradhan Source Type: research
Usefulness of B-type Natriuretic Peptides to Predict Cardiovascular Events in Women (from the Women's Health Study)
Natriuretic peptides are positively associated with incident cardiovascular disease (CVD), but data in women, particularly with regard to improvements in risk prediction, are sparse. We measured the N-terminal prohormone form of B-type natriuretic peptide (NT-proBNP) in 480 cases of incident CVD (myocardial infarction, stroke, and cardiovascular death) and a reference subcohort of 564 women from the Women's Health Study who were followed for a median of 12.0 (interquartile range 7.6 to 13.4) years.
Source: The American Journal of Cardiology - May 21, 2015 Category: Cardiology Authors: Brendan M. Everett, Paul M Ridker, Nancy R. Cook, Aruna D. Pradhan Tags: Preventive Cardiology Source Type: research
Cardiac Complications after Community-acquired Pneumonia
We read with interest the article by Cangemi et al “Relation of cardiac complications in the early phase of community –acquired pneumonia to long-term mortality and cardiovascular events”1 published in the August 5th issue of The American Journal of Cardiology. The authors show that 18% of patients with community-acquired pneumonia (CAP) study develop intra-hospital cardiac complications, defined as myocardial infarction (MI) and atrial fibrillation. Furthermore, the authors prospectively show that these cardiac complications in the early phase of CAP are associated with adverse long-term cardiovascular prognosis (wi...
Source: The American Journal of Cardiology - October 15, 2015 Category: Cardiology Authors: Carlos G. Santos-Gallego, Juan Badimon Source Type: research
Predictive Value of Combining the Ankle-Brachial Index and SYNTAX Score for the Prediction of Outcome after Percutaneous Coronary Intervention (From the SHINANO Registry)
The SYNTAX score is effective in predicting clinical outcome after percutaneous coronary intervention (PCI). However, its prediction ability is low because it reflects only the coronary characterization. We assessed the predictive value of combining the ankle-brachial index (ABI) and SYNTAX score to predict clinical outcomes after PCI. The ABI-SYNTAX score was calculated for 1197 patients recruited from the SHINANO registry, a prospective, observational, multi-center cohort study in Japan. The primary endpoints were major adverse cardiovascular and cerebrovascular events (MACE; all-cause death, myocardial infarction, and s...
Source: The American Journal of Cardiology - November 5, 2015 Category: Cardiology Authors: Yasushi Ueki, Takashi Miura, Yusuke Miyashita, Hirohiko Motoki, Kentaro Shimada, Masanori Kobayashi, Hiroyuki Nakajima, Hikaru Kimura, Hiroshi Akanuma, Eiichiro Mawatari, Toshio Sato, Shoji Hotta, Yuichi Kamiyoshi, Takuya Maruyama, Noboru Watanabe, Takayu Source Type: research
Meta-analysis of Transcatheter Aortic Valve Replacement Versus Surgical Aortic Valve Replacement in patients with Severe Aortic Valve Stenosis Patients
Transcatheter aortic valve replacement (TAVR) is a viable option in the treatment of severe aortic stenosis in patients at high risk for surgery. We sought to further investigate outcomes in low-to-intermediate-risk patients with aortic stenosis undergoing surgical aortic valve replacement (SAVR) versus TAVR. We systematically searched the electronic databases, MEDLINE, PUBMED, EMBASE and Cochrane for prospective cohort studies of the effects of TAVR vs SAVR on clinical outcomes (30-day mortality, all cause mortality, stroke and myocardial infarction [MI], major vascular complications, paravalvular regurgitation, permanent...
Source: The American Journal of Cardiology - November 5, 2015 Category: Cardiology Authors: Ashok Kondur, Alexandros Briasoulis, Mohan Palla, Anirudh Penumetcha, Sagar Mallikethi-Reddy, Apurva Badheka, Theodore Schreiber Source Type: research
Effects of Oral Anticoagulant Therapy in Medical In-patients ≥65 Years of Age with Atrial Fibrillation
In this retrospective cohort observational study we investigated mortality, ischemic and hemorrhagic events, in patients ≥65 years of age with atrial fibrillation (AF) consecutively discharged from an Acute Geriatric Ward in the period 2010-2013. Stroke and bleeding risk were evaluated using CHA2DS2-VASC and HAS-BLED scores. Comorbidity, cognitive status and functional autonomy were evaluated using standardized scales. Independent associations between clinical variables, including use of Vitamin K Antagonists (VKAs)-based oral anticoagulant therapy (OAT), and all-cause mortality, fatal and non-fatal ischemic and hemorrha...
Source: The American Journal of Cardiology - December 1, 2015 Category: Cardiology Authors: Mario Bo, Irene Sciarrillo, Federica Li Puma, Marco Badinella Martini, Yolanda Falcone, Marina Iacovino, Enrica Grisoglio, Elena Menditto, Gianfranco Fonte, Enrico Brunetti, Guido Maggiani, Giovanni Carlo Isaia, Fiorenzo Gaita Source Type: research
Trends in Ideal cardiovascular Health Metrics Among Employees of a Large Healthcare Organization (From the Baptist Health South Florida Employee Study)
The American Heart Association’s (AHA) 2020 goal is to improve the cardiovascular health (CVH) of people living in the United States by 20% and reduce mortality from cardiovascular diseases (CVD) and stroke by 20%. Given that 155 million adults are in the U.S workforce, and over 60% have employee-based insurance, workplace studies provide an important opportunity to assess, and potentially advance CVH through the use of comprehensive workplace wellness programs. Among a cohort of employees of the Baptist Health System, CVH was assessed annually during voluntary health fairs and health risk assessments (HRA) from 2011-201...
Source: The American Journal of Cardiology - December 13, 2015 Category: Cardiology Authors: Oluseye Ogunmoroti, Ovie Utuama, Erica S. Spatz, Maribeth Rouseff, Don Parris, Sankalp Das, Adnan Younus, Henry Guzman, Thinh Tran, Arthur Agatston, Theodore Feldman, Salim S. Virani, Wasim Maziak, Emir Veledar, Khurram Nasir Source Type: research
Treatment of Massive or Submassive Acute Pulmonary Embolism with Catheter Directed Thrombolysis
The presentation of acute pulmonary thromboembolism (PE) can be highly variable resulting in diagnostic challenges and management difficulties. Current guidelines suggest that therapy must be adjusted based on the severity of PE presentation. Systemic thrombolysis is the standard therapy for acute massive pulmonary embolism (PE), however systemic thrombolysis carries an estimated 20% risk of major hemorrhage, including a 3%-5% risk of hemorrhagic stroke. There are data supporting the use of catheter directed therapy (CDT) in massive and sub-massive PE, but past studies have limited its use to patients in whom systemic thro...
Source: The American Journal of Cardiology - December 31, 2015 Category: Cardiology Authors: Ashraf Mostafa, Alexandros Briasoulis, Tesfaye Telila, Kevin Belgrave, Cindy Grines Source Type: research
Anticoagulation, CHADSVASc Score and Thromboembolic Risk of Cardioversion of Acute Atrial Fibrillation (from the FinCV Study)
The efficacy of the anticoagulation in prevention thromboembolic complications (TEC) and the usefulness of the CHA2DS2VASc score for assessing stroke risk during cardioversion of acute atrial fibrillation (AF) are unclear. Thus, our objectives were to assess the ability of the CHA2DS2VASc score to predict TEC and to evaluate the efficacy of anticoagulation in the prevention of TEC in Finnish CardioVersion (FinCV) study. The FinCV is a retrospective, multicenter study of 3143 patients, who underwent 7660 cardioversions for acute AF.
Source: The American Journal of Cardiology - January 28, 2016 Category: Cardiology Authors: Toni Grönberg, Juha E.K. Hartikainen, Ilpo Nuotio, Fausto Biancari, Antti Ylitalo, K. E. Juhani Airaksinen Source Type: research
Relation Between Change in Renal Function and Cardiovascular Outcomes in Atorvastatin-Treated Patients (From the Treating to New Targets TNT Study)
Statins may have nephroprotective as well as cardioprotective effects in patients with cardiovascular disease. In the Treating to New Targets (TNT) study (NCT00327691), patients with coronary heart disease (CHD) were randomized to atorvastatin 10- or 80-mg/day and followed for 4.9 years. The relationship between intra-study change in estimated glomerular filtration rate (eGFR) from baseline and the risk of major cardiovascular events (MCVE, defined as CHD death, nonfatal non-procedure-related myocardial infarction, resuscitated cardiac arrest or fatal or nonfatal stroke) was assessed among 9500 patients stratified by renal...
Source: The American Journal of Cardiology - January 28, 2016 Category: Cardiology Authors: James Shepherd, Andrei Breazna, Prakash C. Deedwania, John C. LaRosa, Nanette K. Wenger, Michael Messig, Daniel J. Wilson, Treating to New Targets Steering Committee and Investigators Source Type: research
Treatment of Massive or Submassive Acute Pulmonary Embolism With Catheter-Directed Thrombolysis
The presentation of acute pulmonary thromboembolism (PE) can be highly variable resulting in diagnostic challenges and management difficulties. Current guidelines suggest that therapy must be adjusted based on the severity of PE presentation. Systemic thrombolysis is the standard therapy for acute massive PE; however, systemic thrombolysis carries an estimated 20% risk of major hemorrhage, including a 3% to 5% risk of hemorrhagic stroke. There are data supporting the use of catheter-directed therapy (CDT) in massive and submassive PE, but past studies have limited its use to patients in whom systemic thrombolysis has eithe...
Source: The American Journal of Cardiology - December 31, 2015 Category: Cardiology Authors: Ashraf Mostafa, Alexandros Briasoulis, Tesfaye Telila, Kevin Belgrave, Cindy Grines Tags: Review Source Type: research
Anticoagulation, CHADSVASc Score, and Thromboembolic Risk of Cardioversion of Acute Atrial Fibrillation (from the FinCV Study)
The efficacy of the anticoagulation in preventing thromboembolic complications (TEC) and the usefulness of the CHA2DS2VASc score for assessing stroke risk during cardioversion of acute atrial fibrillation (AF) are unclear. Thus, our objectives were to assess the ability of the CHA2DS2VASc score to predict TEC and to evaluate the efficacy of anticoagulation in the prevention of TEC in Finnish CardioVersion (FinCV) study. The FinCV is a retrospective, multicenter study of 3,143 patients, who underwent 7,660 cardioversions for acute AF.
Source: The American Journal of Cardiology - January 28, 2016 Category: Cardiology Authors: Toni Grönberg, Juha E.K. Hartikainen, Ilpo Nuotio, Fausto Biancari, Antti Ylitalo, K.E. Juhani Airaksinen Tags: Arrhythmias and Conduction Source Type: research
Anticoagulation, CHA2DS2VASc Score, and Thromboembolic Risk of Cardioversion of Acute Atrial Fibrillation (from the FinCV Study)
The efficacy of the anticoagulation in preventing thromboembolic complications (TEC) and the usefulness of the CHA2DS2VASc score for assessing stroke risk during cardioversion of acute atrial fibrillation (AF) are unclear. Thus, our objectives were to assess the ability of the CHA2DS2VASc score to predict TEC and to evaluate the efficacy of anticoagulation in the prevention of TEC in Finnish CardioVersion (FinCV) study. The FinCV is a retrospective, multicenter study of 3,143 patients, who underwent 7,660 cardioversions for acute AF.
Source: The American Journal of Cardiology - January 28, 2016 Category: Cardiology Authors: Toni Grönberg, Juha E.K. Hartikainen, Ilpo Nuotio, Fausto Biancari, Antti Ylitalo, K.E. Juhani Airaksinen Tags: Arrhythmias and Conduction Source Type: research
Relation of Non-Valvular Atrial Fibrillation to Body Mass Index (From the SPORTIF Trials)
Obesity is well-established as a major cardiovascular (CV) risk factor. Obesity confers a higher risk for developing atrial fibrillation (AF), but the relation between obesity and established non-valvular AF (NVAF) for stroke and all-cause death is still unclear. To ascertain the prevalence of overweight and obesity in NVAF patients, their influence on adverse events and the relation with anticoagulation control we performed this post-hoc analysis of the pooled SPORTIF III and V datasets. For this study, we analysed all patients assigned to the warfarin arm with data on body mass index(BMI).
Source: The American Journal of Cardiology - April 19, 2016 Category: Cardiology Authors: Marco Proietti, Deirdre A. Lane, Gregory Y.H. Lip Source Type: research
Utility of Global Longitudinal Strain by Echocardiography to Detect Left Ventricular Dysfunction in Long-Term Adult Survivors of Childhood Lymphoma and Acute Lymphoblastic Leukemia
Measuring left ventricular (LV) global longitudinal strain (GLS) is recommended in screening of long-term cancer survivors for cardiotoxicity. However, there are limited data on GLS in this setting, in particular in survivors with apparently normal LV function without risk factors of impaired GLS. In the present study, we measured GLS in 191 adult survivors of childhood lymphoma or acute lymphoblastic leukemia, with normal LV ejection fraction (EF) and fractional shortening (FS), and without known hypertension, diabetes mellitus, myocardial infarction or stroke.
Source: The American Journal of Cardiology - May 13, 2016 Category: Cardiology Authors: Jon R. Christiansen, Richard Massey, Håvard Dalen, Adriani Kanellopoulos, Hanne Hamre, Sophie D. Fosså, Ellen Ruud, Cecilie E. Kiserud, Svend Aakhus Source Type: research
