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Source: The American Journal of Cardiology
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Total 366 results found since Jan 2013.

OP-137 Does Electrocardiographic Diastolic Index Predict Asymptomatic Atrial Fibrillation in Patients with Dual-chamber Pacemaker?
Asymptomatic atrial fibrillation episodes detected by pacemaker is known to increase the risk of systemic embolism and stroke by 2-3 times in patients with dual-chamber pacemaker. Atrial high-rate episodes presence together with duration of episodes is also an important indicator of adverse events. The studies have shown the relationship between the electrocardiographic diastolic index and the development of diastolic dysfunction. The aim of our study was to show the relationship between the ECG index (Tend-P/[PQxAge]) and atrial fibrillation in patients with dual-chamber pacemaker.
Source: The American Journal of Cardiology - March 12, 2015 Category: Cardiology Authors: Ahmet Ilker Tekkesin, Emrah Bozbeyoglu, Ozlem Yildirimturk, Ceyhan Turkkan, Yasin Cakilli, Ahmet Murat, Mert Ilker Hayiroglu, Ahmet Taha Alper Tags: Oral Abstract Source Type: research

Effect of Gender on Patients with ST-elevation and Non-ST-elevation Myocardial Infarction without Obstructive Coronary Artery Disease
We compared the prognosis of patients with ST-elevation MI (STEMI) with non-ST-elevation MI (NSTEMI) without obstructive coronary artery disease (CAD) and the risk associated with gender for future cardiovascular (CV) events. The study population was selected from 95,849 patients undergoing coronary angiography for MI during the period 2005-2010 and registered in the Swedish Coronary Angiography and Angioplasty Registry. Outcome analyses, including all-cause death, MI, congestive heart failure (CHF), stroke and revascularization, were performed on 2268 STEMI patients and 10,904 NSTEMI patients without obstructive CAD (
Source: The American Journal of Cardiology - March 24, 2015 Category: Cardiology Authors: Nina Johnston, Birgitta Jönelid, Christina Christersson, Tanja Kero, Henrik Renlund, Karin Schenck-Gustafsson, Bo Lagerqvist Source Type: research

Relation between Dabigatran Concentration, as Assessed Using the Direct Thrombin Inhibitor Assay, and Activated Clotting Time/Activated Partial Thromboplastin Time in Patients with Atrial Fibrillation
In this study, we aimed to assess the associations between the dabigatran concentration (calculated via plasma-diluted thrombin time, as assessed using the Hemoclot® assay) and the activated partial thromboplastin time (aPTT) and activated clotting time (ACT). We recruited 137 patients with atrial fibrillation who were receiving a normal dose of dabigatran (300 mg/day) or a reduced dose of dabigatran (220 mg/day, usually administered to patients who were elderly, had moderate renal dysfunction, or who were also receiving verapamil).
Source: The American Journal of Cardiology - March 25, 2015 Category: Cardiology Authors: Kenji Okubo, Taishi Kuwahara, Katsumasa Takagi, Masateru Takigawa, Jun Nakajima, Yuji Watari, Emiko Nakashima, Kazuya Yamao, Tadashi Fujino, Hiroyuki Tsutsui, Atsushi Takahashi Source Type: research

Metaanalysis of Comparison Between Self-Expandable and Balloon- Expandable Valves for Patients Having Transcatheter Aortic Valve Implantation
Two different devices, one self-expanding and one balloon-expandable, have been developed for patients undergoing transcatheter aortic valve implantation (TAVI) with contrasting data about efficacy and safety. Pubmed, Medline and Google Scholar were systematically searched for studies these different devices, with data derived from randomized controlled trial or registries with multivariate analysis. All cause death at 30 days and at follow-up were the primary end points, while post procedural moderate or severe aortic regurgitation, stroke, major vascular complications, bleedings and pacemaker implantation the secondary ones.
Source: The American Journal of Cardiology - March 26, 2015 Category: Cardiology Authors: Claudio Moretti, Fabrizio D’Ascenzo, Marco Mennuni, Salma Taha, Nedy Brambilla, Freek Nijhoff, Chiara Fraccaro, Marco Barbanti, Corrado Tamburino, Giuseppe Tarantini, Marco Luciano Rossi, Patrizia Presbitero, Massimo Napodanno, Pieter Stella, Francesco Source Type: research

Comparison of Five-year Outcome of Percutaneous Coronary Intervention to Coronary Artery Bypass Grafting in Triple Vessel Coronary Artery Disease (From CREDO-Kyoto PCI/CABG Registry Cohort-2)
Studies evaluating long-term (>=5-year) outcomes of percutaneous coronary intervention (PCI) using drug-eluting stents compared with coronary artery bypass grafting (CABG) in patients with triple vessel coronary artery disease (TVD) are still limited. We identified 2978 patients with TVD (PCI: N=1824, CABG: N=1154) among 15939 patients with first coronary revascularization enrolled in the CREDO-Kyoto PCI/CABG registry cohort-2. The primary outcome measure in the current analysis was a composite of death, myocardial infarction (MI), and stroke.
Source: The American Journal of Cardiology - April 6, 2015 Category: Cardiology Authors: Hiroki Shiomi, Takeshi Morimoto, Yutaka Furukawa, Yoshihisa Nakagawa, Junichi Tazaki, Ryuzo Sakata, Hitoshi Okabayashi, Michiya Hanyu, Mitsuomi Shimamoto, Noboru Nishiwaki, Tatsuhiko Komiya, Takeshi Kimura, CREDO-Kyoto PCI/ CABG registry cohort-2 investig Source Type: research

Balancing the Risk of Bleeding and Stroke in Patients with Atrial Fibrillation after Percutaneous Coronary Intervention (from the AVIATOR-registry)
We describe patterns and determinants of antithrombotic prescriptions in this population. The AVIATOR (Antithrombotic strategy Variability In ATrial fibrillation and Obstructive coronary disease Revascularized with PCI) Registry was an international observational study of 859 consecutive patients with AF undergoing PCI between 2009 and 2011.
Source: The American Journal of Cardiology - April 7, 2015 Category: Cardiology Authors: Marco G. Mennuni, Jonathan L. Halperin, Sameer Bansilal, Mikkel M. Schoos, Kleanthis N. Theodoropoulos, Omar A. Meelu, Samantha Sartori, Daniele Giacoppo, Chiara Bernelli, Pedro R. Moreno, Prakash Krishnan, Usman Baber, Carla Lucarelli, George D. Dangas, Source Type: research

Meta-analysis of Comparison Between Self-Expandable and Balloon-Expandable Valves for Patients Having Transcatheter Aortic Valve Implantation
Two different devices, 1 self-expanding and 1 balloon-expandable, have been developed for patients who underwent transcatheter aortic valve implantation with contrasting data about efficacy and safety. Pubmed, Medline, and Google Scholar were systematically searched for studies of these different devices, with data derived from randomized controlled trial or registries with multivariate analysis. All-cause death at 30 days and at follow-up were the primary end points, whereas postprocedural moderate or severe aortic regurgitation (AR), stroke, major vascular complications, bleedings, and pacemaker implantation the secondary ones.
Source: The American Journal of Cardiology - March 26, 2015 Category: Cardiology Authors: Claudio Moretti, Fabrizio D'Ascenzo, Marco Mennuni, Salma Taha, Nedy Brambilla, Freek Nijhoff, Chiara Fraccaro, Marco Barbanti, Corrado Tamburino, Giuseppe Tarantini, Marco L. Rossi, Patrizia Presbitero, Massimo Napodanno, Pieter Stella, Francesco Bedogni Tags: Valvular Heart Disease Source Type: research

Impact of Visit-to-visit Variability and Systolic Blood Pressure Control on Subsequent Outcomes in Hypertensive Patients with Coronary Artery Disease (From the HIJ-CREATE Sub-study)
Although visit-to-visit variability in systolic blood pressure (BP) is a strong predictor of stroke, the impact on subsequent major adverse cardiovascular events (MACE) in patients with coronary artery disease (CAD) in terms of secondary prevention remains unclear. The aim of this study was to clarify the prognostic significance of visit-to-visit variability in systolic BP on subsequent MACE in hypertensive patients with CAD. In the HIJ-CREATE trial, a total of 2,049 hypertensive patients with CAD were enrolled.
Source: The American Journal of Cardiology - April 20, 2015 Category: Cardiology Authors: Hiroyuki Arashi, Hiroshi Ogawa, Jun-ichi Yamaguchi, Erisa Kawada-Watanabe, Nobuhisa Hagiwara Source Type: research

Earlobe Crease Shapes and Cardiovascular Events
The objectives were to define the ELC using a single-blind approach and to determine through multivariate analysis its association with cardiovascular events (CVEs) comprising coronary, ischaemic cerebrovascular and peripheral vascular diseases. A single-blind cross-sectional study was performed in 2 phases: (1) an initial study (n=300) to define ELC classification criteria and (2) a confirmation stage (n=1000) to analyse ELC association with CVEs.
Source: The American Journal of Cardiology - April 22, 2015 Category: Cardiology Authors: Claudia Rodríguez-López, Hugo Garlito-Díaz, Raquel Madroñero-Mariscal, Pablo Jesús Sánchez-Cervilla, Auxiliadora Graciani, José Luis López-Sendón, Esteban López-de-Sá Source Type: research

Balancing the Risk of Bleeding and Stroke in Patients With Atrial Fibrillation After Percutaneous Coronary Intervention (from the AVIATOR Registry)
We describe patterns and determinants of antithrombotic prescriptions in this population. The Antithrombotic Strategy Variability in Atrial Fibrillation and Obstructive Coronary Disease Revascularized with PCI Registry was an international observational study of 859 consecutive patients with AF who underwent PCI from 2009 to 2011.
Source: The American Journal of Cardiology - April 7, 2015 Category: Cardiology Authors: Marco G. Mennuni, Jonathan L. Halperin, Sameer Bansilal, Mikkel M. Schoos, Kleanthis N. Theodoropoulos, Omar A. Meelu, Samantha Sartori, Daniele Giacoppo, Chiara Bernelli, Pedro R. Moreno, Prakash Krishnan, Usman Baber, Carla Lucarelli, George D. Dangas, Tags: Coronary Artery Disease Source Type: research

Comparison of Five-Year Outcome of Percutaneous Coronary Intervention With Coronary Artery Bypass Grafting in Triple-Vessel Coronary Artery Disease (from the Coronary Revascularization Demonstrating Outcome Study in Kyoto PCI/CABG Registry Cohort-2)
Studies evaluating long-term (≥5 years) outcomes of percutaneous coronary intervention (PCI) using drug-eluting stents compared with coronary artery bypass grafting (CABG) in patients with triple-vessel coronary artery disease (TVD) are still limited. We identified 2,978 patients with TVD (PCI: n = 1,824, CABG: n = 1,154) of 15,939 patients with first coronary revascularization enrolled in the Coronary Revascularization Demonstrating Outcome Study in Kyoto PCI/CABG Registry Cohort-2. The primary outcome measure in the present analysis was a composite of death, myocardial infarction (MI), and stroke.
Source: The American Journal of Cardiology - April 6, 2015 Category: Cardiology Authors: Hiroki Shiomi, Takeshi Morimoto, Yutaka Furukawa, Yoshihisa Nakagawa, Junichi Tazaki, Ryuzo Sakata, Hitoshi Okabayashi, Michiya Hanyu, Mitsuomi Shimamoto, Noboru Nishiwaki, Tatsuhiko Komiya, Takeshi Kimura, the CREDO-Kyoto PCI/ CABG Registry Cohort-2 Inve Tags: Coronary Artery Disease Source Type: research

Impact of Heart Disease on Maternal and Fetal Outcomes in Pregnant Women
In this study, we sought to identify the risk and risk factors for adverse maternal and fetal events in pregnant women with underlying heart disease. Pregnant women referred for echocardiogram with known or suspected heart disease were categorized into those with: (1) cardiomyopathy, (2) other heart disease (HD; congenital, coronary, arrhythmia, or valvular), and (3) no HD. Primary outcome was major adverse cardiovascular events (MACE), defined as a composite of death, sustained arrhythmia, myocardial infarction, heart failure, and transient ischemic attack/stroke.
Source: The American Journal of Cardiology - May 8, 2015 Category: Cardiology Authors: Paraskevi Koutrolou-Sotiropoulou, Puja B. Parikh, Charles Miller, Fabio Vasconcelos Lima, Javed Butler, Kathleen Stergiopoulos Source Type: research

Comparison of 2-Year Outcomes of Extended Criteria Cardiac Transplantation versus Destination Left Ventricular Assist Device Therapy Using Continuous Flow
Alternatives have emerged for patients ineligible for cardiac transplantation under standard criteria (SCCT). The purpose of our study was to compare outcomes in patients ineligible for SCCT, treated either with extended criteria cardiac transplantation (ECCT) or a continuous flow destination therapy left ventricular assist device (CF DT-LVAD). From 2005 to 2012, patients treated with either ECCT or CF DT-LVAD at our institution were retrospectively analyzed. In the overall unmatched cohort, we examined mortality and other outcomes, including index hospitalization length of stay, renal function, stroke, and readmission rates.
Source: The American Journal of Cardiology - May 20, 2015 Category: Cardiology Authors: Mani A. Daneshmand, Arun Krishnamoorthy, Marc D. Samsky, G. Michael Felker, John A. Pura, Yuliya Lokhnygina, Adrian F. Hernandez, Paul B. Rosenberg, Laura J. Blue, Jacob N. Schroder, Joseph G. Rogers, Carmelo A. Milano, Chetan B. Patel Source Type: research

Meta-analysis of CHADS Score in Predicting Atrial Fibrillation
The CHADS2 score is a validated clinical tool used for the risk stratification of stroke in the presence of atrial fibrillation (AF). Recently, some studies have shown that CHADS2 score may predict the risk of AF, which yielded conflicting results. The purpose of this study is to perform a meta-analysis of observational studies to examine the association between the CHADS2 score and risk of AF. Using PubMed and EMBASE database, we searched published articles to November 2014 to identify studies which evaluated the association between CHADS2 score and the risk of AF.
Source: The American Journal of Cardiology - May 20, 2015 Category: Cardiology Authors: Yajuan Yang, Zhiwei Zhang, Chee Yuan Ng, Guangping Li, Tong Liu Source Type: research

Relation Of Cardiac Complications In The Early Phase Of Community-Acquired Pneumonia To Long-Term Mortality And Cardiovascular Events
Community-acquired pneumonia (CAP) is complicated by cardiac events in the early phase of the disease. Aim of this study was to assess if these intra-hospital cardiac complications may account for overall mortality and cardiovascular events occurring during a long-term follow up. Three hundred and one consecutive patients admitted to the University-Hospital, Policlinico Umberto I, with CAP were prospectively recruited and followed-up for a median of 17.4 months). Primary end-point was the occurrence of death for any cause and secondary endpoint was the occurrence of cardiovascular events (cardiovascular death, non-fatal my...
Source: The American Journal of Cardiology - May 21, 2015 Category: Cardiology Authors: Roberto Cangemi, Camilla Calvieri, Marco Falcone, Tommaso Bucci, Giuliano Bertazzoni, Maria Gabriella Scarpellini, Francesco Barillà, Gloria Taliani, Francesco Violi, in collaboration with the SIXTUS study group Source Type: research