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Total 826 results found since Jan 2013.
Application of digital practice to improve head movement, visual perception and activities of daily living for subacute stroke patients with unilateral spatial neglect: Preliminary results of a single-blinded, randomized controlled trial
Conclusions:
VR-based digital practice program might be an affordable approach for visual perception and head movement recovery for subacute stroke patients with USN.
Source: Medicine - February 12, 2021 Category: Internal Medicine Tags: Research Article: Clinical Trial/Experimental Study Source Type: research
The effect of transcranial direct current stimulation combined with functional task training on motor recovery in stroke patients
This study protocol was registered in Clinical Trials Registry (https://clinicaltrials.gov/ct2/show/NCT04646577).
Ethics and dissemination:
The study has been reviewed and approved by the Human Research Ethics Committee of the King Fahad Specialist Hospital Dammam. The results will be actively disseminated through peer-reviewed journals, conference presentations, social media, broadcast media, print media, the internet and various community/stakeholder engagement activities.
Source: Medicine - February 12, 2021 Category: Internal Medicine Tags: Research Article: Study Protocol Clinical Trial Source Type: research
Effects of autophagy inhibitor 3-Methyladenine on ischemic stroke: A protocol for systematic review and meta-analysis
Discussion:
This systematic review and meta-analysis of the autophagy inhibitor 3-MAs effects on animal models of ischemic stroke can help us to understand whether inhibiting autophagy brings protection or damage to IP neurons; in addition, it also helps to clarify the specific role of autophagy in cerebral infarction. Therefore, this study can provide evidence for the future development of therapy strategies targeting autophagy and bring more hope to patients with ischemic stroke.
PROSPERO registration number:
CRD42020194262.
Source: Medicine - January 29, 2021 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research
Efficacy and safety of massage in the treatment of poststroke depression: A systematic review and meta-analysis of protocols
Conclusion:
It will be substantiated in this review whether massage therapy is a reliable intervention for poststroke depression by examining the evidence collected.
INPLASY registration number:
INPLASY2020110085.
Source: Medicine - January 29, 2021 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research
Effect of education and muscle relaxation program on anxiety, depression and care burden in caregivers of acute stroke survivors: A randomized, controlled study
This study intended to discover the effect of education and muscle relaxation (EMR) program on anxiety, depression and care burden among caregivers of acute stroke survivors.
This randomized, controlled study enrolled a total of 110 caregivers of first-ever acute stroke patients, and randomly assigned to EMR (N = 55) and control (N = 55) groups. The caregivers in the EMR group received 12-month health education and progressive muscle relaxation, and those in control group were provided common rehabilitation advices. Hospital Anxiety and Depression Scale (HADS) and Zarit Caregiver Burden Scale in caregivers were ...
Source: Medicine - January 29, 2021 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
How demographic and clinical characteristics contribute to the recovery of post-stroke dysphagia?
According to the analysis to find out how demographic and clinical characteristics influent the dysphagia outcome after stroke, furthermore, giving some insights to clinical treatment.
One hundred eighty post-stroke dysphagia (PSD) patients were enrolled in this retrospective study at the stroke rehabilitation department. The outcome measurements are beside water swallow test at discharge and length of stay at hospital. Twenty-five demographic and clinical variables were collected for this study. Logistic regression and multilinear regression were utilized to estimate models to identify the risk and protect predictors o...
Source: Medicine - January 29, 2021 Category: Internal Medicine Tags: Research Article: Diagnostic Accuracy Study Source Type: research
Simultaneous cardio-cerebral infarction in the coronavirus disease pandemic era: A case series
Conclusion:
Early recognition and immediate treatment is important in different scenarios leading to thrombosis as the outcome. Additionally, addressing the unknown risks that could contribute to our traditional understanding of these causative mechanisms is important. The hypothesis of exacerbated damage caused by inflammatory and immunological endothelial systemic damage should further be explored to be able to delineate new possibilities in managing these conditions.
Source: Medicine - January 29, 2021 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Acupuncture combined with moxibustion for insomnia after stroke: A protocol for systematic review and meta analysis
Conclusion:
The conclusion of our study will provide the updated evidence to judge the effectiveness and safety of acupuncture combined with moxibustion for the treatment of insomnia after stroke.
Trial registration number:
PROSPERO CRD42020216720.
Source: Medicine - January 22, 2021 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research
Efficacy of minimally invasive surgery for the treatment of hypertensive intracerebral hemorrhage: A protocol of randomized controlled trial
Conclusions:
The findings of the study will be helpful for the choice of MIS and conservative treatment when treating HICH patients.
Trial registration:
OSF Registration number: DOI 10.17605/OSF.IO/ME6Y5.
Source: Medicine - January 22, 2021 Category: Internal Medicine Tags: Research Article: Study Protocol Clinical Trial Source Type: research
Early physical rehabilitation vs standard care for intracerebral hemorrhage stroke: A protocol for systematic review and meta-analysis
Background:
The intracerebral hemorrhagic stroke (ICH) is associated with high mortality and severe disability in survivors, which causing about 42% of the disability-adjusted life years lost and 50% of all stroke patients dead within 1 year. Although early functional training is recommended to facility rehabilitation after the stroke, the benefit and safety are still controversial.
Introduction:
This systematic review aims to investigate whether early physical rehabilitation could have a beneficial effect for the patients with ICH compared with standard rehabilitation care.
Methods and analysis:
Pubmed, ...
Source: Medicine - January 22, 2021 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research
Graded motor imagery training as a home exercise program for upper limb motor function in patients with chronic stroke: A randomized controlled trial
Purpose:
Although several types of occupational therapy for motor recovery of the upper limb in patients with chronic stroke have been investigated, most treatments are performed in a hospital or clinic setting. We investigated the effect of graded motor imagery (GMI) training, as a home exercise program, on upper limb motor recovery and activities of daily living (ADL) in patients with stroke.
Methods:
This prospective randomized controlled trial recruited 42 subjects with chronic stroke. The intervention group received instruction regarding the GMI program and performed it at home over 8 weeks (30 minutes ...
Source: Medicine - January 22, 2021 Category: Internal Medicine Tags: Research Article: Clinical Trial/Experimental Study Source Type: research
Effectiveness and safety of different doses of tenecteplase in the treatment of acute ischemic stroke: A protocol for systematic review and meta-analysis
Conclusion:
This study will provide reliable evidence-based evidence for the clinical application of different doses of tenecteplase in thrombolytic therapy for acute ischemic stroke.
OSF Registration number:
DOI 10.17605/OSF.IO/2MPCW.
Source: Medicine - January 22, 2021 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research
Clinical outcomes of multivessel coronary artery disease patients revascularized by robot-assisted vs conventional standard coronary artery bypass graft surgeries in real-world practice
The treatment of patients with multivessel coronary artery disease (MVD) by coronary stenting (PCI) and the “gold standard” conventional coronary-artery bypass grafting (C-CABG) has been well explored in the literature. However, the clinical outcomes of robot-assisted CABG (R-CABG) vs C-CABG in MVD patients in real-world practice were unknown. We aimed to study the clinical outcomes of MVD patients who underwent R-CABG (robotic MIDCAB) and C-CABG at our institution between January 2005 and December 2013.
A total of 516 MVD patients received CABG were recruited into this study. Among them, 281 patients received R-CAB...
Source: Medicine - January 22, 2021 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
CHADS2, CHA2DS2-VASc, ATRIA, and Essen stroke risk scores in stroke with atrial fibrillation: A nationwide multicenter registry study
The performance of scoring systems for risk stratification in patients with atrial fibrillation (AF) was not validated well in patients with stroke. The purpose of this study was to evaluate whether the risk scoring systems predict vascular outcomes in stroke patients with AF.
Data were obtained from a nationwide multicenter registry for acute stroke with AF from January 1, 2013, to December 31, 2015. We investigated the predictive power of the CHADS2, CHA2DS2-VASc, ATRIA, and Essen stroke scores in stroke patients with AF. The subjects were further stratified into groups according to treatment with or without oral anti...
Source: Medicine - January 22, 2021 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
Optimal intervention time and risk of the activating blood and removing stasis method in acute cerebral hemorrhage patients: A randomized placebo-controlled trial
Discussion:
The study is expected to confirm the safety and effect of acute cerebral hemorrhage within 24 to 72 hours treated with the ABRS method and to determine the optimal time for intervention in this period.
Trial registration number:
ChiCTR1900022627
Source: Medicine - January 15, 2021 Category: Internal Medicine Tags: Research Article: Study Protocol Clinical Trial Source Type: research
