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Source: Thrombosis and Haemostasis
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Total 312 results found since Jan 2013.
Survey on APS diagnosis and antithrombotic treatment in patients with ischaemic stroke, other brain ischaemic injury or arterial thromboembolism in other sites: Communication from ISTH SSC Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibodies (LA/aPL)
CONCLUSIONS: Much of the variation in practice reflects the lack of evidence-based recommendations. The survey results should inform the development of a more uniform multidisciplinary consensus approach to diagnosis and antithrombotic treatment.PMID:37391096 | DOI:10.1016/j.jtha.2023.06.020
Source: Thrombosis and Haemostasis - June 30, 2023 Category: Hematology Authors: Hannah Cohen David J Werring Arvind Chandretheva Prabal Mittal Katrien M J Devreese David A Isenberg ISTH SSC LA/aPL Subcommittee Study Group Source Type: research
Coagulation biomarkers for ischemic stroke
We report on coagulation biomarker-induced risk of IS, stroke severity, and outcomes following IS derived from prospective population studies, case-control studies, and acute-phase IS studies. We found indications that many coagulation and inflammation biomarkers are associated with IS, but it is early to conclude that any of these biomarkers can be applied in a therapeutic setting to predict patients at risk of IS, stroke severity at the acute phase, and clinical outcome after treatment. The strongest evidence for a role in IS was found for beta-thromboglobulin, von Willebrand factor, factor VIII, fibrinogen, thrombin-act...
Source: Thrombosis and Haemostasis - June 5, 2023 Category: Hematology Authors: Aarazo Barakzie A J Gerard Jansen Hugo Ten Cate Moniek P M de Maat Source Type: research
Thrombotic Complications in Children with COVID-19 and MIS-C
J Thromb Haemost. 2023 May 31:S1538-7836(23)00434-8. doi: 10.1016/j.jtha.2023.05.020. Online ahead of print.ABSTRACTCoronavirus disease 2019 (COVID-19) associated coagulopathy is multifactorial and involves inflammation driven hypercoagulability, endothelial dysfunction, platelet activation and impaired fibrinolysis. Hospitalized adults with COVID-19 are at an increased risk of both venous thrombo-embolism (VTE) and ischemic stroke, resulting in adverse outcomes including mortality. While children with COVID-19 follow a less severe course, both arterial and venous thrombosis have been reported in hospitalized children with...
Source: Thrombosis and Haemostasis - June 2, 2023 Category: Hematology Authors: Riten Kumar Michael J Rivkin Leslie Raffini Source Type: research
Platelet versus plasma CXCL14, coronary artery disease, and clinical outcomes
CONCLUSION: Platelet-associated and circulating CXCL14 levels show differential regulation in patients with and without CAD. Although platelet-associated CXCL14 increased and circulating CXCL14 decreased with impairment of LVEF, only lower circulating CXCL14 upon admission was associated with worse prognosis in patients with CAD.PMID:37255851 | PMC:PMC10225916 | DOI:10.1016/j.rpth.2023.100165
Source: Thrombosis and Haemostasis - May 31, 2023 Category: Hematology Authors: Christoph Schories Peter Martus Tianyun Guan Jessica Kristin Henes Alexander Witte Karin M üller Tobias Geisler Madhumita Chatterjee Meinrad Gawaz Dominik Rath Source Type: research
Mobile Health-Technology-Integrated Care for Atrial Fibrillation: A Win Ratio Analysis from the mAFA-II Randomized Clinical Trial
CONCLUSIONS: In this posthoc WR analysis of the mAFA-II trial, a mHealth-technology-implemented integrated care approach was effective in reducing the risk of the primary composite outcome of all-cause death, ischemic stroke or thromboembolism, and rehospitalization, even when prioritizing fatal events.PMID:37247623 | DOI:10.1055/s-0043-1769612
Source: Thrombosis and Haemostasis - May 29, 2023 Category: Hematology Authors: Giulio Francesco Romiti Yutao Guo Bernadette Corica Marco Proietti Hui Zhang Gregory Y H Lip mAF-App II trial investigators Source Type: research
Frailty and subsequent adverse outcomes in older patients with atrial fibrillation treated with oral anticoagulants: The Shizuoka study
CONCLUSION: Patients with frailty in whom OAC therapy is initiated have higher risk of bleeding, highlighting the importance of discussing this increased risk with patients with AF who have frailty and assessing frailty at the time of OAC initiation.PMID:37168397 | PMC:PMC10165150 | DOI:10.1016/j.rpth.2023.100129
Source: Thrombosis and Haemostasis - May 11, 2023 Category: Hematology Authors: Shiori Nishimura Hiraku Kumamaru Satoshi Shoji Eiji Nakatani Hiroyuki Yamamoto Nao Ichihara Alexander T Sandhu Yoshiki Miyachi Hiroaki Miyata Shun Kohsaka Source Type: research
C-reactive protein and D-dimer in cerebral vein thrombosis: Relation to clinical and imaging characteristics as well as outcomes in a French cohort study
CONCLUSION: Two widely available biomarkers measured upon admission, especially hs-CRP, could help predict bad prognosis in CVST in addition to patient characteristics. These results need to be validated in other cohorts.PMID:37138790 | PMC:PMC10149398 | DOI:10.1016/j.rpth.2023.100130
Source: Thrombosis and Haemostasis - May 4, 2023 Category: Hematology Authors: Paul Billoir Virginie Siguret Elisabeth Masson Fron Ludovic Drouet Isabelle Crassard Rapha ël Marlu Marianne Barbieux-Guillot Pierre-Emmanuel Morange Emmanuelle Robinet Catherine Metzger Val érie Wolff Elisabeth Andr é-Kerneis Fr édéric Klapczynski B Source Type: research
Atrial fibrillation in cancer: thromboembolism and bleeding in daily practice
CONCLUSION: Patients with AF and active cancer experience high rates of thromboembolic and bleeding complications, underlying the complexity of anticoagulant management in these patients. Our data suggest that the presence of cancer is an important factor in determining the indication for anticoagulants in patients with a low CHA2DS2-VASc score.PMID:37063771 | PMC:PMC10099322 | DOI:10.1016/j.rpth.2023.100096
Source: Thrombosis and Haemostasis - April 17, 2023 Category: Hematology Authors: Gordon Chu Jaap Seelig Suzanne C Cannegieter Hans Gelderblom Marcel M C Hovens Menno V Huisman Tom van der Hulle Serge A Trines Andr é J Vlot Henri H Versteeg Martin E W Hemels Frederikus A Klok Source Type: research
Elevated thrombin generation levels in the left atrial appendage in patients with atrial fibrillation
CONCLUSION: In patients with AF undergoing catheter ablation, the LAA demonstrated increased thrombin generation compared with the LA. This finding might contribute to the understanding of why the LAA is more predisposed to thrombus formation than the LA.CLINICAL TRIALS REGISTRATION: NCT03795883.PMID:37063762 | PMC:PMC10099305 | DOI:10.1016/j.rpth.2023.100127
Source: Thrombosis and Haemostasis - April 17, 2023 Category: Hematology Authors: Adi Elias Yara Khoury Faheem Shehadeh Gilat Ron Monther Boulos Jeries Nashashibi Robert Zukermann Mazen Elias Lior Gepstein Mahmoud Suleiman Source Type: research
