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Association of beta-2-microglobulin, cystatin C and lipocalin-2 with stroke risk in the general Chinese population
CONCLUSION: Elevated serum B2M, cystatin C and LCN-2 levels are associated with stroke risk. They may be novel biomarkers for clinicians to assess stroke risk.Key messagesSerum beta-2-microglobulin, cystatin C and lipocalin-2 levels are significantly associated with stroke risk.Beta-2-microglobulin, cystatin C and lipocalin-2 may serve as useful biomarkers for stroke risk stratification in the general population.PMID:37155257 | PMC:PMC10167872 | DOI:10.1080/07853890.2023.2203516
Source: Annals of Medicine - May 8, 2023 Category: Internal Medicine Authors: Juanying Zhen Shuyun Liu Ryan Yan Lam Kam Guoru Zhao Hao Peng Jianguo Liang Aimin Xu Chao Li Lijie Ren Jun Wu Bernard Man Yung Cheung Source Type: research

24-hour ambulatory blood pressure and cryptogenic ischemic stroke in young adults
CONCLUSIONS: Non-dipping patterns of BP were associated with CIS in the absence of a PFO but not in the absence of hypertension. This may reflect differing pathophysiology underlying CIS in patients with versus without a PFO. Due to limitations of the study, results regarding absolute ABP levels should be interpreted with caution.Key MessagesNocturnal non-dipping patterns of blood pressure were associated with cryptogenic ischemic stroke except in participants with a patent foramen ovale and in those without hypertension by any definition, which may indicate differing pathophysiology underlying cryptogenic ischemic stroke ...
Source: Annals of Medicine - April 24, 2023 Category: Internal Medicine Authors: Lauri Tulkki Nicolas Martinez-Majander Petri Haapalahti Heli Tolppanen Juha Sinisalo Olli Repo Tomi Sarkanen Heikki Numminen Essi Ry ödi Pauli Ylikotila Risto O Roine Riikka Lautam äki Antti Saraste Tuuli Miettinen Jaana Autere Pekka J äkälä Marja He Source Type: research

Outcome of transcatheter atrial septal defect closure in a nationwide cohort
CONCLUSION: After TC closure of ASD, patients had a higher risk of new-onset atrial fibrillation and migraine than controls without ASD. As novel findings, we found an increased risk for ischemic heart disease, AV conduction disorders, and ventricular fibrillation/tachycardia.Key messagesEven though patients have an excellent overall prognosis after percutaneous ASD closure, the increased incidence of major comorbidities like atrial fibrillation and heart failure prompts more thorough lifelong follow-up.This study's novel findings revealed the increased risk for ischemic heart disease, AV conduction disorders, or ventricul...
Source: Annals of Medicine - February 14, 2023 Category: Internal Medicine Authors: V Muroke M Jalanko J Haukka J Hartikainen A Tahvanainen H Ukkonen K Ylitalo J Pihkala J Sinisalo Source Type: research

Self-reported efficacy in patient-physician interaction in relation to anxiety, patient activation, and health-related quality of life among stroke survivors
CONCLUSIONS: Higher self-efficacy in patient-physician interaction was associated with higher patient activation and mental health status among stroke survivors using smartwatches. Furthermore, we found no association between anxiety and smartwatch prescription for AF in participants with high self-efficacy in patient-physician interaction. Efforts to improve self-efficacy in patient-physician interaction may improve patient activation and self-rated health and subsequently may lead to better clinical outcomes.KEY MESSAGESHigher self-efficacy in patient-physician interaction was associated with higher patient activation an...
Source: Annals of Medicine - February 1, 2023 Category: Internal Medicine Authors: Jordy Mehawej Khanh-Van T Tran Andreas Filippaios Tenes Paul Hawa O Abu Eric Ding Ajay Mishra Qiying Dai Essa Hariri Sakeina Howard Wilson Jean-Claude Asaker Joanne Mathew Syed Naeem Edith Mensah Otabil Apurv Soni David D McManus Source Type: research

Trajectories of arm recovery early after stroke: an exploratory study using latent class growth analysis
CONCLUSIONS: We found unique patterns of arm recovery with distinct characteristics for each cluster. Better understanding of patterns of arm recovery can guide future models and intervention development.KEY MESSAGESArm recovery early after stroke follows four distinct trajectories that relate to time post stroke, initial stroke severity and baseline level of motor arm function.Identification of recovery patterns gives insight into the uniqueness of individual's recovery.This study offers a novel approach on which to build and develop future models of arm recovery.PMID:36594373 | DOI:10.1080/07853890.2022.2159062
Source: Annals of Medicine - January 3, 2023 Category: Internal Medicine Authors: Angela Vratsistas-Curto Aron Downie Annie McCluskey Catherine Sherrington Source Type: research

Clinical profile and risk factors of cerebral venous sinus thrombosis (CVST) in Sudan: A multicenter cross-sectional study
CONCLUSION: Cerebral Venous Sinus Thrombosis is mainly a disease of child-bearing women, although significant proportions of men were affected. Cerebral Venous Sinus Thrombosis presents in a wide variety of signs and symptoms.PMID:36536723 | PMC:PMC9758368 | DOI:10.1016/j.amsu.2022.104891
Source: Annals of Medicine - December 20, 2022 Category: Internal Medicine Authors: Etedal Ahmed A Ibrahim Rofiedah Eisa Hassan Mohamed Khabab Abbasher Hussien Mohamed Ahmed Mazin S Haroun Yassin Abdelrahim Abdalla Mohammed Eltahier Abdalla Omer Mohammed Mahmmoud Fadelallah Eljack Source Type: research

Dysphagia and associated factors among patients with acute ischemic stroke in Vietnam
CONCLUSION: Our study showed that the prevalence of dysphagia is high among patients with acute ischemic stroke in Vietnam. Intervention solutions should focus more on patient groups of higher age group, brainstem stroke, communication disorder and facial paralysis.PMID:36536715 | PMC:PMC9758358 | DOI:10.1016/j.amsu.2022.104887
Source: Annals of Medicine - December 20, 2022 Category: Internal Medicine Authors: Nguyen Thi Thu Hien Tran Huu Thong Le Thanh Tung Vo Hong Khoi Dao Thi Thu Hoai Tran Thi Tinh Nguyen Van Huy Vu Duy Kien Source Type: research

Clinical profile and risk factors of cerebral venous sinus thrombosis (CVST) in Sudan: A multicenter cross-sectional study
CONCLUSION: Cerebral Venous Sinus Thrombosis is mainly a disease of child-bearing women, although significant proportions of men were affected. Cerebral Venous Sinus Thrombosis presents in a wide variety of signs and symptoms.PMID:36536723 | PMC:PMC9758368 | DOI:10.1016/j.amsu.2022.104891
Source: Annals of Medicine - December 20, 2022 Category: Internal Medicine Authors: Etedal Ahmed A Ibrahim Rofiedah Eisa Hassan Mohamed Khabab Abbasher Hussien Mohamed Ahmed Mazin S Haroun Yassin Abdelrahim Abdalla Mohammed Eltahier Abdalla Omer Mohammed Mahmmoud Fadelallah Eljack Source Type: research

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