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The Pasteurian contribution to the history of vaccines
C R Biol. 2022 Sep 13;345(3):93-107. doi: 10.5802/crbiol.83.ABSTRACTVaccination, the transmission of "vaccine", a benign disease of cows, to immunize human beings against smallpox, was invented by Jenner at the end of the eighteenth century. Pasteur, convinced that the vaccine microbe was an attenuated form of the smallpox microbe, showed that, similarly, attenuated forms of other microbes immunized against animal diseases. When applying this principle to rabies, he realized that, in this case, the vaccine was in fact composed of dead microbes. One of his students immediately exploited this result to devise a vaccine again...
Source: Comptes Rendus Biologies - February 28, 2023 Category: Biology Authors: Maxime Schwartz Source Type: research