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E-105 Analysis of clinical associations of serum SCFAs taken at the time of thrombectomy in AIS patients
ConclusionsThe evaluation of SCFAs in the serum at the time of stroke provides novel insight into the potential role of SCFAs during stroke in human patients. Age remains a significant factor to SCFA concentrations in stroke patients. The length of time following stroke also contributes to the levels of SCFAs. Previous studies have shown that increased levels of SCFAs is associated with decreased severity of stroke, however our data did not detect any such effect. This observation may be due to the acute time of the blood collection following stroke and analyzing serum instead of fecal samples. Furthermore, acquiring infor...
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Henry, N., Frank, J., Fraser, J., Trout, A., Morris, A., Chen, J., Stowe, A., McLouth, C., Pennypacker, K. Tags: Electronic poster abstracts Source Type: research

P-026 Aqua embolic system: evaluating the performance of a new liquid embolic system using a swine AVM model
ConclusionsAES, which is a DMSO free, non-adhesive polysaccharides based LEM, may be used as an embolic material for the treatment of hemorrhagic stroke caused by cerebrovascular diseases, such as brain AVM.A: common carotid artery injection (AP view) shows left ascending pharyngeal artery (APA) and left rete mirabile (red arrow). B: AES is injected from the microcatheter. The AES reflux is reaching the tip of the microcatheter. C: With continuous injection of AES, the microcotheter tip is embedded ¡n the cost of AES. D. Post treatment angiogram shows complete occlusion of the left rete mirabile and APADisclosures I....
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Yuki, I., Ohkawa, K., Li, S., Steward, E., Nguyen, B., Hsu, F., Xu, J., Suzuki, S. Tags: Oral poster abstracts Source Type: research

E-027 Matricidal cavernous aneurysms: a multicenter case series
Conclusion Matricidal aneurysms require careful consideration and planning. The restricted anatomy of the cavernous sinus can make successful execution of endovascular interventions difficult. Direct elastic compression of the parent artery does not respond to angioplasty and stenting the way that atherosclerotic stenosis does. Because of this, planning for possible parent vessel sacrifice is important. Abstract E-027 Table 1 Intended Treatments and Outcomes n Intended Treatment Failed Treatment (rate) All Patients 37 10 (27%) Flow Diversion 18 5 (28%) Parent Vessel Sacrifice 11 With Bypass 4 2 (50%) Without Bypass 7 0 ...
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Roberts, M., Nickele, C., Welch, B., Ban, V., Ringer, A., Kim, L., Levitt, M., Lanzino, G., Kan, P., Shallwani, H., Siddiqui, A., Elijovich, L., Arthur, A. Tags: Electronic Poster Abstracts Source Type: research

E-076 Embotrap thrombectomy and subsequent embolic events
Conclusion Based on this preliminary study, it is our conclusion that stent retriever design can be optimized to alter the particle size distribution of distal emboli. When encountering friable hard clots, the use of the EmboTrap device may provide a reduction in distal emboli to both affected and unaffected territories and should be considered. Disclosures: J. Chueh: None. M. Marosfoi: None. R. King: None. O. Brooks: None. A. Puri: None. M. Gounis: 1; C; research grant. 6; C; Travel Support.
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Chueh, J., Marosfoi, M., King, R., Brooks, O., Puri, A., Gounis, M. Tags: Electronic Poster Abstracts Source Type: research

E-077 Laboratory analogs of challenging thromboemboli in acute ischemic stroke
Conclusion Thrombus analogs with mechanical characteristics similar to those of challenging clinical thrombi were successfully developed. The calcium apatite thrombus analog was found to be stiffer than the fibrin-rich thrombus analog. References . Saver JL et al: Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. N Engl J Med 2015, 372(24):2285–2295. . Dorn F et al: Endovascular treatment of acute intracerebral artery occlusions with the solitaire stent: single-centre experience with 108 recanalization procedures. Cerebrovasc Dis 2012, 34(1):70–77. Disclosures: J. Chueh: None. J....
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Chueh, J., Litchman, J., Arslanian, R., Carniato, S., Rex, D., Howk, M., Gounis, M., Puri, A. Tags: Electronic Poster Abstracts Source Type: research

O-013 Hypertension Decreases the Number and Duration of Collateral Openings during Middle Cerebral Artery Occlusion (MCAO) and Impairs Reperfusion
ConclusionsThese results demonstrate that collateral flow during ischemia, and reperfusion, was impaired in hypertension likely due to vasoconstriction of LMAs. Understanding the function of pial collaterals under conditions such as hypertension, that is associated with little penumbral tissue, may provide targeted therapies to prevent collateral failure and extend the time window for treatment in these patients.DisclosuresM. Cipolla: 1; C; NIH grants. J. Sweet: None. K. Chan: None.
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Cipolla, M., Sweet, J., Chan, K. Tags: Oral abstracts Source Type: research

Authors reply
We greatly appreciate the response of Mehta and colleagues to our paper. The ADAPT FAST study was an unfunded multicenter registry conducted independently by a group of committed physicians in an effort to further the understanding of stroke treatment. This was not a grant-funded prospective randomized trial. Revascularization assessments were made by the operators rather than a blinded independent core laboratory. We certainly acknowledge the limitations inherent in the design of the study. At the same time, despite these limitations, we feel that our study provides an important initial assessment of the safety and effica...
Source: Journal of NeuroInterventional Surgery - June 11, 2016 Category: Neurosurgery Authors: Turner, R., Fiorella, D., Mocco, J., Frei, D., Baxter, B., Siddiqui, A., Spiotta, A., Chaudry, I., Turk, A. S. Tags: PostScript Source Type: research

E-013 unchanged utilization of endovascular treatment in acute ischemic stroke patients in the post ims-iii era
ConclusionContrary to expectations, there has been no reduction in the utilization of endovascular treatment among acute ischemic stroke patients after IMS-III, MR RESCUE and SYNTHESIS EXPANSION results were published.Abstract E-013 Table 1Pre and Post IMS III Pre-IMS III Post-IMS III P-value Patients with ischemic stroke (%)6765 (50.5)6643 (49.5)Mechanical thrombectomy155 (2.3)161 (2.4)0.6IV tPA483 (7.1)520 (7.8)0.1Discharge dispositionHome or self care3135 (46.6)3079 (46.3)Skilled nursing facility1529 (22.6)1486 (22.4)Expired268 (4.0)253 (3.8)0.3Length of stay in hospital3.8 ± 4.13.6 ± 3.50.02Hospital c...
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Hassan, A., Bezzina, C., Malik, A., Sanchez, C., Tekle, W., Qureshi, A. Tags: SNIS 12th Annual Meeting Electronic Poster Abstracts Source Type: research

E-070 the surpass intracranial aneurysm embolization system pivotal trial to treat large or giant wide neck aneurysms (scent trial)
ConclusionThe SCENT trial is currently enrolling and is expected to complete enrollment by mid-2015.DisclosuresA. Puri: 1; C; Research grant from Stryker. 2; C; Codman and Covidien. R. Hanel: 2; C; Stryker, Codman and Covidien. 4; C; Blockade. 5; C; Scientific advisory board- Medina medical. P. Meyers: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Puri, A., Hanel, R., Meyers, P. Tags: SNIS 12th Annual Meeting Electronic Poster Abstracts Source Type: research

E-139 in vivo perfusion imaging using magnetic particle imaging
ConclusionMPI shows great promise as a sensitive, high-contrast, and radiation-free technique for measuring brain perfusion, brain vasculature, and organ perfusion.AcknowledgmentsThe authors acknowledge support from the following research grants: NIH 5R01EB013689–03, CIRM RT2–01893, Keck Foundation 034317, NIH 1R24MH106053–01, NIH 1R01EB019458–01, ACTG 037829, and NIH 2R42EB013520–02A1.ReferencesWintermark M, et al. Stroke, 2005:e83Weizenecker J, et al. PMB 2009;54(5)Rahmer J, et al. PMB 2013;58(12):3965–77Saritas E, et al. JMR 2013;229:116–26Ferguson, et alet al. IEEE-TMI, in pres...
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Goodwill, P., Ferguson, M., Yu, E., Zheng, B., Lu, K., Khandhar, A., Kemp, S., Krishnan, K., Conolly, S. Tags: SNIS 12th Annual Meeting Electronic Poster Abstracts Source Type: research

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