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O-038 Sympathetic nervous system activation causes cerebral perfusion deficit and cerebral vasoconstriction in Swine
ConclusionIn swine, electrical stimulation of SCG results in reproducible cerebral vasoconstriction and perfusion deficit comparable to cerebral vasospasm. This can be inhibited by prior local anesthetic injection into the SCG, a possible therapeutic target for cerebral vasospasm.Abstract O-038 Figure 1CT perfusion scan (top row) coronel view of approximate fronto-temporal area of swine brain (outlined in white box) at baseline, with right SCG stimulation, with lidocainc + right SCG stimulation. Cerebral angiogram (bottom row) AP view of swine cranial artcrics at baseline, with right SCG stimulation, with lidocaine + right...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Kim, W., Samarage, M., Zarrin, D., Goel, K., Johnson, J., Wang, A., Colby, G. Tags: SNIS 19th annual meeting oral abstracts Source Type: research

O-054 Prospective study on embolization of intracranial aneurysms with the pipeline device (PREMIER study): 3-year results with the application of a specific flow-diverter occlusion classification
ConclusionsA high rate of aneurysm occlusion, low morbidity, and absence of aneurysm rupture emphasize the PED as a safe treatment strategy for small and medium-sized aneurysms located along the ICA and VA in the long term.Disclosures R. Hanel: 1; C; Unrestricted research grant from NIH, Interline Endowment, Microvention, Stryker, CNX. 2; C; Medtronic, Stryker, Cerenovous, Microvention, Balt, Phenox, Rapid Medical, and Q’Apel. He is on advisory board for MiVI, eLum, Three Rivers, Shape Medical and Corindus. 4; C; InNeuroCo, Cerebrotech, eLum, Endostream, Three Rivers Medical Inc, Scientia, RisT, BlinkTBI, and Corindu...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Hanel, R., Cortez, G., Lopes, D., Nelson, P., Siddiqui, A., Jabbour, P., Pereira, V., Istvan, I., Zaidat, O., Bettegowda, C., Colby, G., Mokin, M., Schirmer, C., Hellinger, F., Given, C., Krings, T., Taussky, P., Toth, G., Fraser, J., Chen, M., Priest, R. Tags: SNIS 19th annual meeting oral abstracts Source Type: research

P-013 Designing and prototyping a novel balloon-stent device for minimally invasive temporary aneurysm occlusion and embolization
ConclusionA balloon-stent device allows for longer neuro-interventional procedures by providing continuous perfusion without arresting blood flow during balloon inflation. In addition, this novel medical device provides a smooth surface at the aneurysm neck for consistent device placement, minimization of parent vessel trauma, elimination of ischemic effects distal to the parent artery, and minimization of intra-saccular flow remnants pre- and post-treatment.Abstract P-013 Figure 1a) FPR results from theoretical estimation, benchtop modeling, and computational fluid dynamic (CFD) simulation. B) balloon component of the bal...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Asgari, O., Fennell, B., Norris, N., Ducruet, A., Becker, T. Tags: SNIS 19th annual meeting oral poster abstracts Source Type: research

E-182 A multicentric experience for the use of flow diverter in the treatment of anterior communicating artery aneurysms
ConclusionFlow diverters appear to be a safe and effective treatment for anterior communicating artery aneurysms, presenting as an alternative strategy in the armamentarium of interventionalist. Mid-term results were favorable, and complication rates were low. Additional studies with longer follow-up time and independent adjudication are warranted to confirm the safety and effectiveness of the technique.Disclosures V. Benalia: None. G. Cortez: None. N. Kocer: None. C. Islak: None. I. Saatci: None. S. Cekirge: None. F. Baltacıoğlu: None. G. Dabus: None. C. Mounayer: None. A. Siddiqui: None. D. Lopes: None. W. ...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Benalia, V., Cortez, G., Kocer, N., Islak, C., Saatci, I., Cekirge, S., Baltacıoglu, F., Dabus, G., Mounayer, C., Siddiqui, A., Lopes, D., Brinjikji, W., Aghaebrahim, A., Sauvageau, E., Hanel, R. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

LB003 Multicenter assessment of the tigertriever 13 for thrombectomy in primary medium vessels occlusions
ConclusionMechanical thrombectomy using the Tigertriever13 appears to be safe and effective for MeVO among different centers and physicians, as a first-line device or as a recue-therapy after an other approach failure.Disclosures A. guenego: 6; C; Travel Grant to PAIRS in Dubai by Rapid Medical. B. lubicz: None. A. Dmytriw: None. R. Regenhardt: None. J. diestro: None. V. pereira: None. P. jabbour: None. J. siegler: None. N. gonzalez: None. M. Levitt: None. I. Tancredi: None. A. Rouchaud: None. J. Fiehler: None. T. Faizy: None. P. Kan: None. X. barreau: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2022 Category: Neurosurgery Authors: Guenego, A., Lubicz, B., Dmytriw, A., Regenhardt, R., Diestro, J., Pereira, V., Jabbour, P., Siegler, J., Gonzalez, N., Levitt, M., Tancredi, I., Rouchaud, A., Fiehler, J., Faizy, T., Kan, P., Barreau, X. Tags: SNIS 19th annual meeting late-breaking oral abstracts Source Type: research

P64 NIMBUS geometric clot extractor for tough clots: SPERO study results and clot composition
ConclusionsIn challenging cases with tough clot, first pass of NIMBUS retrieved clot richer in fibrin and lower in RBC content than clot retrieved with the first pass of standard MT devices.ReferencesFennell VS, Setlur Nagesh SV, Meess KM, Gutierrez L, James RH, Springer ME, Siddiqui AH. What to Do about Fibrin Rich ‘Tough Clots’? Comparing the Solitaire Stent Retriever with a Novel Geometric Clot Extractor in an in vitro Stroke Model. J Neurointerv Surg 2018 Sep;10(9):907–910. DOI: 10.1136/Neurintsurg-2017-013507. EPUB 2018 Jan 19. PMID: 29352061. Do you have any conflict of interest to declare?: YesConf...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: van den Berg, R., Ribo, M., Arnberg, F., Estrade, L., Thornton, J., Tomasello Weitz, A., Gontu, V., Karam, A., Hernandez, D., Clarencon, F., Buhk, J.-H., Wiesmann, M., Nouri, N., Bricout, N., Desal, H., Januel, A., Doyle, K., Liebeskind, D., Brouwer, P., Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

P77 Predictors of good clinical outcome after thrombectomy for distal medium vessel occlusions
ConclusionAn older age, a longer puncture to recanalization time and a higher baseline core volume were strongly associated with poor clinical outcomes, while successful recanalization (mTICI 2c-3) was associated with better outcomes after MT for DMVO.ReferencesGuenego A, Mine B, Bonnet T, et al. Thrombectomy for distal medium vessel occlusion with a new generation of stentretriever (tigertriever 13). Interv Neuroradiol 2021: 15910199211039926. 2021/09/14. DOI: 10.1177/15910199211039926. Do you have any conflict of interest to declare?: YesConflict of Interest StatementConsultancy for Rapid Medical (travel grant only)
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Guenego, A., Lubicz, B. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

P79 Multicenter assessment of the Tigertriever 13 for thrombectomy in primary medium vessels occlusions
ConclusionMechanical thrombectomy using the Tigertriever 13 appears to be safe and effective for MeVO among different centers and physicians, as a first-line device or as a recue-therapy after an other approach failure.ReferencesGuenego A, Mine B, Bonnet T, et al. Thrombectomy for distal medium vessel occlusion with a new generation of stentretriever (tigertriever 13). Interv Neuroradiol 2021: 15910199211039926. 2021/09/14. DOI: 10.1177/15910199211039926. Do you have any conflict of interest to declare?: YesConflict of Interest StatementConsultancy for Rapid Medical (travel grant only)
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Guenego, A., Lubicz, B., Dmytriw, A., Regenhardt, R., Diestro, J., Jabbour, P., Siegler, J., Gonzalez, N., Levitt, M., Tancredi, I., Rouchaud, A., Fiehler, J., Kan, P., Berge, J., Nedelcu, S., Ota, T., Yeo, L., Sheth, S., Collin, T., Renieri, L., Mowla, A Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

E-065 Interim safety and occlusion outcomes of endovascular treatment of large intracranial aneurysms in the sterling registry
ConclusionEarly results from the STERLING registry for large aneurysms are promising. Adequate occlusion per Independent Core Lab was achieved in 86.7% and retreatment rates were relatively low over 1-year follow-up. A good functional outcome was achieved in 85.7% of patientsDisclosures O. Zaidat: 1; C; Stryker, Medtronic, Cerenovus, Penumbra, and Genentech. 2; C; Stryker, Medtronic, Cerenovus, Penumbra, and Neuravi. 4; C; ownership interest in Galaxy Therapeutics LLC;. 6; C; honoraria from Codman,Stryker,Penumbra, Medtronic. serves on the endovascular committee as co-chair for NIH StrokeNet Consortium; has served as an ex...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Zaidat, O., Ashouri, Y., Starke, R., Puri, A., Jankowitz, B., Yoo, A., Marnat, G., Kulcsar, Z., Sugiu, K., Jahshan, S., Machi, P., Pero, G., Castro, S., Howington, J., Schirmer, C., Kilburg, C., Chivot, C., Al-Mufti, F., Da Ros, V., Gory, B., Yao, T., Pol Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

P133/254 Clinical significance of subarachnoid hyper densities on flat panel CT after mechanical thrombectomy - does it matter?
ConclusionPostinterventional SH are a frequent finding after MT and are associated with neurological decline and an unfavourable outcome. They are more common with distal occlusions and multiple device passes.Disclosure of InterestFD serves as a consultant/proctor for Balt, Cerenovus, Microvention, received scientific grant from Cerenovus and received speaker honoraria from Acandis, Asahi, Stryker.
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Mousa, Z., Dorn, F., Bode, F., Petzold, G., Weller, J., Paech, D. Tags: 2.2 ISCHEMIC - Imaging Source Type: research

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