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Routine or selective carotid artery shunting for carotid endarterectomy (and different methods of monitoring in selective shunting)
CONCLUSIONS: This review concluded that the data available were too limited to either support or refute the use of routine or selective shunting in carotid endarterectomy when performed under general anaesthesia. Large-scale randomised trials of routine shunting versus selective shunting are required. No method of monitoring in selective shunting has been shown to produce better outcomes.PMID:35731671 | PMC:PMC9216235 | DOI:10.1002/14651858.CD000190.pub4
Source: Cochrane Database of Systematic Reviews - June 22, 2022 Category: General Medicine Authors: Busaba Chuatrakoon Sothida Nantakool Amaraporn Rerkasem Saritphat Orrapin Dominic Pj Howard Kittipan Rerkasem Source Type: research

Interventions for reducing sedentary behaviour in people with stroke
CONCLUSIONS: Sedentary behaviour research in stroke seems important, yet the evidence is currently incomplete, and we found no evidence for beneficial effects. Current World Health Organization (WHO) guidelines recommend reducing the amount of sedentary time in people with disabilities, in general. The evidence is currently not strong enough to guide practice on how best to reduce sedentariness specifically in people with stroke. More high-quality randomised trials are needed, particularly involving participants with mobility limitations. Trials should include longer-term interventions specifically targeted at reducing tim...
Source: Cochrane Database of Systematic Reviews - June 29, 2021 Category: General Medicine Authors: David H Saunders Gillian E Mead Claire Fitzsimons Paul Kelly Frederike van Wijck Olaf Verschuren Karianne Backx Coralie English Source Type: research

Patches of different types for carotid patch angioplasty.
CONCLUSIONS: The number of outcome events is too small to allow conclusions, and more trial data are required to establish whether any differences do exist. Nevertheless, there is little to no difference in effect on perioperative and long-term ipsilateral stroke between vein and any synthetic patch material. Some evidence indicates that other synthetic patches (e.g. PTFE) may be superior to Dacron grafts in terms of perioperative stroke and TIA rates, and both early and late arterial re-stenosis and occlusion. Pseudoaneurysm formation may be more common after use of a vein patch than after use of a synthetic patch. Bovin...
Source: Cochrane Database of Systematic Reviews - February 18, 2021 Category: General Medicine Authors: Orrapin S, Benyakorn T, Howard DP, Siribumrungwong B, Rerkasem K Tags: Cochrane Database Syst Rev Source Type: research

Pharmacological, psychological and non-invasive brain stimulation interventions for preventing depression after stroke.
CONCLUSIONS: The available evidence suggests that pharmacological interventions and psychological therapy may prevent depression and improve mood after stroke. However, there is very low certainty in these conclusions because of the very low-certainty evidence. More trials are required before reliable recommendations can be made about the routine use of such treatments after stroke. PMID: 32390167 [PubMed - in process]
Source: Cochrane Database of Systematic Reviews - May 10, 2020 Category: General Medicine Authors: Allida S, Cox KL, Hsieh CF, House A, Hackett ML Tags: Cochrane Database Syst Rev Source Type: research