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Drug: Melatonin
Nutrition: Diets

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Total 335 results found since Jan 2013.

Melatonin Supplementation Reduces Nighttime Blood Pressure But Does Not Affect Blood Pressure Reactivity in Normotensive Adults on a High Sodium Diet
In conclusion, melatonin supplementation did not alter BP reactivity to the perturbations tested on a HSD but may be beneficial in lowering BP in young healthy normotensive adults.PMID:37642281 | DOI:10.1152/ajpregu.00101.2023
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - August 29, 2023 Category: Physiology Authors: Macarena Ramos Gonzalez Michael R Axler Kathryn E Kaseman Andrea J Lobene William B Farquhar Melissa A Witman Danielle L Kirkman Shannon L Lennon Source Type: research

Melatonin ameliorates atherosclerosis by suppressing S100a9-mediated vascular inflammation
Eur J Pharmacol. 2023 Aug 23:175965. doi: 10.1016/j.ejphar.2023.175965. Online ahead of print.ABSTRACTAtherosclerosis (AS)-associated cardiovascular diseases are predominant causes of morbidity and mortality worldwide. Melatonin, a circadian hormone with anti-inflammatory activity, may be a novel therapeutic intervention for AS. However, the exact mechanism is unclear. This research intended to investigate the mechanism of melatonin in treating AS. Melatonin (20 mg/kg/d) was intraperitoneally administered in a high-fat diet (HFD)-induced AS model using apolipoprotein E-deficient (ApoE-/-) mice for 12 weeks. Immunohistochem...
Source: European Journal of Pharmacology - August 25, 2023 Category: Drugs & Pharmacology Authors: Liyuan Chen Xue Wang Chang Liu Ping Deng Lina Pan Lingling Yang Juan Cheng Xutao Zhang Russel J Reiter Zhengping Yu Huifeng Pi Zhou Zhou Houyuan Hu Source Type: research

Melatonin associated with a high-fat diet during pregnancy and lactation prevents liver changes in the offspring
In conclusion, melatonin combined with a high-fat diet preserves the liver architecture and function in the offspring.PMID:37586542 | DOI:10.1016/j.ygcen.2023.114357
Source: General and Comparative Endocrinology - August 16, 2023 Category: Endocrinology Authors: Clovis J C Lapa Neto Ismaela M F de Melo Paloma K B M Alpiovezza Yuri M L de Albuquerque An ísio Francisco Soares Álvaro A C Teixeira Val éria Wanderley-Teixeira Source Type: research