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Drug: Melatonin
Management: European Medicines Agency (EMA)
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Total 2 results found since Jan 2013.
Assessment of dim light melatonin onset based on plasma and saliva samples
Chronobiol Int. 2022 Feb 15:1-10. doi: 10.1080/07420528.2021.2016796. Online ahead of print.ABSTRACTMelatonin (MELA) is a nocturnal hormone involved in the regulation of the circadian rhythm. MELA can be detected in plasma and saliva, and its salivary concentration strongly correlates with its plasma concentration. Dim light melatonin onset (DLMO) is considered to be the most accurate objective marker for assessing the circadian phase. The purpose of the study was to establish a method for the determination of MELA in plasma and saliva based on the liquid chromatography with tandem mass spectrometry (LC-MS/MS) and compare ...
Source: Chronobiology International - February 16, 2022 Category: Biology Authors: Micha ł Mateusz Dermanowski Arkadiusz Hejduk Julita Kuczy ńska Adam Wichniak Agnieszka Urba ńska Pawe ł Mierzejewski Source Type: research
