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Source: J Physiol Pharmacol
Drug: Magnesium

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Total 110 results found since Jan 2013.

Oxidative stress responses and their alterations in the Nrf2-NMDA receptor pathway in the brain of suicide victims
This study aimed to investigate the relationship between oxidative stress progression, Nrf2 regulation, and N-methyl-D-aspartate receptor (NMDA) subunit composition in the hippocampus (Hp) and frontal cortex (FCx) of suicide victims (n=14) and matched controls (n=8). Furthermore, zinc and magnesium concentrations and their potency to inhibit [3H] MK-801 (radioactively labeled form of MK-801 - dizocilpine, a well-characterized NMDAR channel uncompetitive antagonist frequently used in receptor-binding assays) binding to NMDA receptor channels were measured. Our results revealed a statistically significant increase in protein...
Source: J Physiol Pharmacol - September 3, 2023 Category: Drugs & Pharmacology Authors: P Panczyszyn-Trzewik P Misztak W Opoka G Nowak M Sowa-Kucma Source Type: research

Varicocelectomy improves sperm parameters, sperm DNA integrity as well as the other critical semen features
In this study, the semen samples from patients with left-side varicocele of grade II-III before and after laparoscopic varicocelectomy were compared to healthy individuals and separated into three groups. The volume of semen, sperm concentration (106/ml), motility (%), viability (%) and normal morphology (%) were assessed. Total antioxidant capacity (TAC), catalase (CAT), superoxide dismutase (SOD) and malondialdehyde (MDA) together with other biochemical substances in seminal plasma as alpha-glucosidase (α-Glu), fructose (Fr) and citric acid (CA) were determined by ELISA method. The spermatozoa activity including ion-tra...
Source: J Physiol Pharmacol - April 23, 2023 Category: Drugs & Pharmacology Authors: Y Nakonechnyi A Nakonechnyi M Fraczek A Havrylyuk M Kamieniczna V Chopyak M Kurpisz Source Type: research