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Total 4663 results found since Jan 2013.

Comparative evaluation of various analgesics in reducing pain in irreversible pulpitis
Bioinformation. 2021 Feb 28;17(2):313-319. doi: 10.6026/97320630017313. eCollection 2021.ABSTRACTIt is of interest to evaluate a single dose of three different analgesics compared to placebo in patients with symptomatic irreversible pulpitis. 120 patients were enrolled with severe pain in this prospective clinical trial. Patients were randomly divided into four groups after shaping and cleaning of root canals. This includes placebo, piroxicam 20mg, acetaminophen 325mg with aceclofenac sodium 100mg and acetaminophen 650mg. Participants were given a questionnaire to note the pain scores at various time intervals (6 hrs, 12 h...
Source: Bioinformation - July 8, 2021 Category: Bioinformatics Authors: Pradeep Solete Sindhu Ramesh Source Type: research

Co-culture with mouse embryonic fibroblasts improves maintenance of metabolic function of human small hepatocyte progenitor cells
Curr Res Toxicol. 2020 Aug 26;1:70-84. doi: 10.1016/j.crtox.2020.08.001. eCollection 2020 Jun 10.ABSTRACTDerivation and culture of small hepatocyte progenitor cells (SHPCs) capable of proliferating in vitro has been described in rodents and recently in humans. These cells are capable of engrafting in injured livers, however, they display de-differentiated morphology and reduced xenobiotic metabolism activity in culture over passages. Here we report that SHPCs derived from adult primary human hepatocytes (PHHs) and cultured on mouse embryonic fibroblasts (MEFs) not only display differentiated morphology and exhibit gene exp...
Source: Cell Research - August 4, 2021 Category: Cytology Authors: Srikumar Sengupta Brian Johnson Morten Seirup Hamisha Ardalani Bret Duffin Gregory A Barrett-Wilt Ron Stewart James A Thomson Source Type: research