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Source: Expert Review of Neurotherapeutics
Drug: Insulin
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Total 379 results found since Jan 2013.
Insulin signaling in the central nervous system, a possible pathophysiological mechanism of anesthesia-induced delayed neurocognitive recovery/postoperative neurocognitive disorder: a narrative review
Expert Rev Neurother. 2022 Nov 4. doi: 10.1080/14737175.2022.2144234. Online ahead of print.ABSTRACTINTRODUCTION: Impairment in neurocognitive functions ranges between delayed neurocognitive recovery (DNR) and postoperative neurocognitive disorders (pNCD). Incidence varies from 11% after non-cardiac surgery to 60% after cardiac surgery.AREAS COVERED: Insulin receptors (IRs) signaling pathway in the central nervous system (CNS) could be a possible pathophysiological mechanism of anesthesia-induced DNR/pNCD and perioperative intranasal insulin administration could be a preventive approach. This hypothesis is supported by the...
Source: Expert Review of Neurotherapeutics - November 4, 2022 Category: Neurology Authors: Ega Qeva Camilla Sollazzo Federico Bilotta Source Type: research
