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Source: Atherosclerosis
Drug: Insulin
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Total 48 results found since Jan 2013.
Triglyceride-glucose index and the incidence of stroke: A meta-analysis of cohort studies
CONCLUSION: A higher TyG index may be independently associated with a higher risk of stroke in individuals without stroke at baseline. The aforementioned findings need to be verified by a large-scale prospective cohort study to further clarify the underlying pathophysiological mechanism between the TyG index and stroke.PMID:36686534 | PMC:PMC9845890 | DOI:10.3389/fneur.2022.1033385
Source: Atherosclerosis - January 23, 2023 Category: Cardiology Authors: Canlin Liao Haixiong Xu Tao Jin Ke Xu Zhennan Xu Lingzhen Zhu Mingfa Liu Source Type: research
Triglyceride-glucose index, symptomatic intracranial artery stenosis and recurrence risk in minor stroke patients with hypertension
CONCLUSION: TyG is a significant risk factor for sICAS in hypertensive patients, and there is a synergistic effect of sICAS and higher TyG on ischemic stroke recurrence.TRIAL REGISTRATION NUMBER: The study was registered on 16 August 2019 at https://www.chictr.org.cn/showprojen.aspx?proj=41160 (No. ChiCTR1900025214).PMID:37076850 | DOI:10.1186/s12933-023-01823-6
Source: Atherosclerosis - April 19, 2023 Category: Cardiology Authors: Yongle Wang Tingting Liu Yanan Li Kaili Zhang Haimei Fan Jing Ren Juan Li Yali Li Xinyi Li Xuemei Wu Junhui Wang Lixi Xue Xiaolei Gao Yuping Yan Gaimei Li Qingping Liu Wenhua Niu Wenxian Du Yuting Liu Xiaoyuan Niu Source Type: research
Impact of Sarcopenia on Functional Outcomes Among Patients With Mild Acute Ischemic Stroke and Transient Ischemic Attack: A Retrospective Study
CONCLUSIONS: In this study, the prevalence of sarcopenia in patients with stroke was lower than most of previous studies and patients with sarcopenia showed higher likelihood for unfavorable functional outcomes at 90 days after acute ischemic stroke or TIA. Further investigation of the interventions for treating sarcopenia and its impact on the outcome of ischemic stroke patients is needed.PMID:35370897 | PMC:PMC8964497 | DOI:10.3389/fneur.2022.841945
Source: Atherosclerosis - April 4, 2022 Category: Cardiology Authors: Hyungwoo Lee Il Hyung Lee JoonNyung Heo Minyoul Baik Hyungjong Park Hye Sun Lee Hyo Suk Nam Young Dae Kim Source Type: research
Triglyceride-glucose index as a prognostic marker after ischemic stroke or transient ischemic attack: a prospective observational study
CONCLUSIONS: TyG index is associated with cervicocerebral atherosclerosis and the MACE risk after a stroke, suggesting the potential value of TyG index to optimize the risk stratification of stroke patients. Trial registration URL: https://upload.umin.ac.jp . Unique identifier: UMIN000031913.PMID:36451149 | DOI:10.1186/s12933-022-01695-2
Source: Atherosclerosis - November 30, 2022 Category: Cardiology Authors: Takao Hoshino Takafumi Mizuno Kentaro Ishizuka Shuntaro Takahashi Satoko Arai Sono Toi Kazuo Kitagawa Source Type: research
Insulin resistance in ischemic stroke: Mechanisms and therapeutic approaches
Front Endocrinol (Lausanne). 2022 Dec 15;13:1092431. doi: 10.3389/fendo.2022.1092431. eCollection 2022.ABSTRACTThe pathological condition of insulin resistance prevents the neuroprotective effects of insulin. Numerous studies have demonstrated that insulin resistance, as an independent risk factor for ischemic stroke, accelerates the formation of thrombosis and promotes the development of atherosclerosis, both of which are major mechanisms of ischemic stroke. Additionally, insulin resistance negatively affects the prognosis of patients with ischemic stroke regardless of whether the patient has diabetes, but the mechanisms ...
Source: Atherosclerosis - January 2, 2023 Category: Cardiology Authors: Peng-Fei Ding Hua-Sheng Zhang Jie Wang Yong-Yue Gao Jian-Nan Mao Chun-Hua Hang Wei Li Source Type: research
Efficacy of Lower Doses of Pioglitazone after Stroke or Transient Ischemic Attack In Patients with Insulin Resistance
CONCLUSIONS: Lower doses of pioglitazone appear to confer much of the benefit with less adverse effects than the full dose. Further study is needed to confirm these findings so that clinicians may optimize dosing of this secondary prevention strategy in stroke patients. This article is protected by copyright. All rights reserved.PMID:35253334 | DOI:10.1111/dom.14687
Source: Atherosclerosis - March 7, 2022 Category: Cardiology Authors: J David Spence Catherine Viscoli Walter N Kernan Lawrence H Young Karen Furie Ralph DeFronzo Muhammad Abdul-Ghani Paresh Dandona Silvio E Inzucchi Source Type: research
Diabetes and Ischemic Stroke: An Old and New Relationship an Overview of the Close Interaction between These Diseases
Int J Mol Sci. 2022 Feb 21;23(4):2397. doi: 10.3390/ijms23042397.ABSTRACTDiabetes mellitus is a comprehensive expression to identify a condition of chronic hyperglycemia whose causes derive from different metabolic disorders characterized by altered insulin secretion or faulty insulin effect on its targets or often both mechanisms. Diabetes and atherosclerosis are, from the point of view of cardio- and cerebrovascular risk, two complementary diseases. Beyond shared aspects such as inflammation and oxidative stress, there are multiple molecular mechanisms by which they feed off each other: chronic hyperglycemia and advanced...
Source: Atherosclerosis - February 26, 2022 Category: Cardiology Authors: Carlo Domenico Maida Mario Daidone Gaetano Pacinella Rosario Luca Norrito Antonio Pinto Antonino Tuttolomondo Source Type: research
Sex differences in the association between stroke risk factors and pre-clinical predictors of stroke in the childhood determinants of Adult Health study
CONCLUSIONS: Smoking, SBP and glucose affect carotid structure and function more in women than men with some of this risk due to co-occurring risk factors.PMID:37391336 | DOI:10.1016/j.atherosclerosis.2023.06.077
Source: Atherosclerosis - June 30, 2023 Category: Cardiology Authors: Mohammad Shah Marie-Jeanne Buscot Jing Tian Hoang T Phan Thomas H Marwick Terence Dwyer Alison Venn Seana Gall Source Type: research
Nuts and seeds consumption and risk of cardiovascular disease, type 2 diabetes and their risk factors: a systematic review and meta-analysis
CONCLUSION: There is a probable relationship between consumption of nuts/seeds and lower risk of CVD, mostly driven by CHD, possibly in part through effects on blood lipids. More research on stroke and T2D may affect the conclusions. The evidence of specific nuts should be further investigated.PMID:36816545 | PMC:PMC9930735 | DOI:10.29219/fnr.v67.8961
Source: Atherosclerosis - February 23, 2023 Category: Cardiology Authors: Erik Kristoffer Arnesen Birna Thorisdottir Linnea B ärebring Fredrik S öderlund Bright I Nwaru Ulrike Spielau Jutta Dierkes Alfons Ramel Christel Lamberg-Allardt Agneta Åkesson Source Type: research
Differentiating Associations of Glycemic Traits with Atherosclerotic and Thrombotic Outcomes: Mendelian Randomization Investigation
Diabetes. 2022 May 2:db210905. doi: 10.2337/db21-0905. Online ahead of print.ABSTRACTWe conducted a Mendelian randomization analysis to differentiate associations of four glycemic indicators with a broad range of atherosclerotic and thrombotic diseases. Independent genetic variants associated with fasting glucose (FG), 2-h glucose after an oral glucose challenge (2hGlu), fasting insulin (FI), and glycated hemoglobin (HbA1c) at the genome-wide significance threshold were used as instrumental variables. Summary-level data for 12 atherosclerotic and 4 thrombotic outcomes were obtained from large genetic consortia and the Finn...
Source: Atherosclerosis - May 2, 2022 Category: Cardiology Authors: Shuai Yuan Amy M Mason Stephen Burgess Susanna C Larsson Source Type: research
