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Insulin resistance estimated by estimated glucose disposal rate predicts outcomes in acute ischemic stroke patients
In this study, we...
Source: Cardiovascular Diabetology - August 26, 2023 Category: Cardiology Authors: Zhengzhao Lu, Yunyun Xiong, Xueyan Feng, Kaixuan Yang, Hongqiu Gu, Xingquan Zhao, Xia Meng and Yongjun Wang Tags: Research Source Type: research

Glyoxal in hyperglycaemic ischemic stroke – a cohort study
Hyperglycaemia is frequent in acute ischemic stroke and denotes a bad prognosis, even in the absence of pre-existing diabetes. However, in clinical trials treatment of elevated glucose levels with insulin did ...
Source: Cardiovascular Diabetology - July 12, 2023 Category: Cardiology Authors: Sina Rhein, Julica Inderhees, Oliver Herrmann, Alaa Othman, Kimberly Begemann, Thomas Fleming, Peter P. Nawroth, Karel D. Klika, Rakad Isa, Inke R. K önig, Georg Royl and Markus Schwaninger Tags: Research Source Type: research

Association between triglyceride-glucose index and all-cause mortality in critically ill patients with ischemic stroke: analysis of the MIMIC-IV database
The triglyceride-glucose (TyG) index was significantly associated with insulin resistance (IR). Several studies have validated the effect of TyG index on cerebrovascular disease. However, the value of TyG inde...
Source: Cardiovascular Diabetology - June 13, 2023 Category: Cardiology Authors: Weimin Cai, Jun Xu, Xiao Wu, Zhuoyan Chen, Liuwei Zeng, Xian Song, Yuan Zeng and Fujun Yu Tags: Research Source Type: research

Triglyceride-glucose index, symptomatic intracranial artery stenosis and recurrence risk in minor stroke patients with hypertension
The triglyceride-glucose (TyG) index, a simple measure of insulin resistance, is associated with intracranial atherosclerosis (ICAS) and stroke. In hypertensive populations, this association may be pronounced....
Source: Cardiovascular Diabetology - April 19, 2023 Category: Cardiology Authors: Yongle Wang, Tingting Liu, Yanan Li, Kaili Zhang, Haimei Fan, Jing Ren, Juan Li, Yali Li, Xinyi Li, Xuemei Wu, Junhui Wang, Lixi Xue, Xiaolei Gao, Yuping Yan, Gaimei Li, Qingping Liu & hellip; Tags: Research Source Type: research

The impact of triglyceride-glucose index on ischemic stroke: a systematic review and meta-analysis
Strokes significantly impair quality of life and incur high economic and societal burdens. The triglyceride and glucose (TyG) index is a biochemical marker of insulin resistance (IR) and may have important val...
Source: Cardiovascular Diabetology - January 6, 2023 Category: Cardiology Authors: Ying Yang, Xiangting Huang, Yuge Wang, Lin Leng, Jiapei Xu, Lei Feng, Shixie Jiang, Jiang Wang, Yanrong Yang, Gaofeng Pan, Bing Jiang, Yan Wang and Lan Chen Tags: Review Source Type: research

Triglyceride-glucose index as a prognostic marker after ischemic stroke or transient ischemic attack: a prospective observational study
Triglyceride-glucose (TyG) index has been proposed as a simple and credible surrogate for insulin resistance and an independent predictor of cardiovascular outcomes. Due to lack of data on TyG index in stroke,...
Source: Cardiovascular Diabetology - November 30, 2022 Category: Cardiology Authors: Takao Hoshino, Takafumi Mizuno, Kentaro Ishizuka, Shuntaro Takahashi, Satoko Arai, Sono Toi and Kazuo Kitagawa Tags: Research Source Type: research

Triglyceride-glucose index trajectory and stroke incidence in patients with hypertension: a prospective cohort study
It has been suggested that the baseline triglyceride-glucose (TyG) index, a simple surrogate measure for insulin resistance, is significantly associated with the occurrence of stroke. Nevertheless, the impact ...
Source: Cardiovascular Diabetology - July 27, 2022 Category: Cardiology Authors: Zegui Huang, Xiong Ding, Qing Yue, Xianxuan Wang, Zekai Chen, Zefeng Cai, Weijian Li, Zhiwei Cai, Guanzhi Chen, Yulong Lan, Weiqiang Wu, Shouling Wu and Youren Chen Tags: Research Source Type: research

Relationship of cumulative exposure to the triglyceride-glucose index with ischemic stroke: a 9-year prospective study in the Kailuan cohort
A single measurement of the triglyceride-glucose (TyG) index, a simple and reliable surrogate marker of insulin resistance, is associated with ischemic stroke. However, evidence for an effect of a long-term el...
Source: Cardiovascular Diabetology - May 3, 2022 Category: Cardiology Authors: Xianxuan Wang, Baoyu Feng, Zegui Huang, Zefeng Cai, Xinran Yu, Zekai Chen, Zhiwei Cai, Guanzhi Chen, Shouling Wu and Youren Chen Tags: Research Source Type: research

Estimated glucose disposal rate and risk of stroke and mortality in type 2 diabetes: a nationwide cohort study
Insulin resistance contributes to the development of type 2 diabetes (T2D) and is also a cardiovascular risk factor. The aim of this study was to investigate the potential association between insulin resistanc...
Source: Cardiovascular Diabetology - October 6, 2021 Category: Cardiology Authors: Alexander Zabala, Vladimer Darsalia, Marcus Lind, Ann-Marie Svensson, Stefan Franz én, Björn Eliasson, Cesare Patrone, Magnus Jonsson and Thomas Nyström Tags: Original investigation Source Type: research

Triglyceride-glucose index and the risk of stroke and its subtypes in the general population: an 11-year follow-up
Triglyceride-glucose (TyG) index was recently suggested to be a reliable surrogate marker of insulin resistance. We aim to investigate the associations between baseline and long-term TyG index with subsequent ...
Source: Cardiovascular Diabetology - February 18, 2021 Category: Cardiology Authors: Anxin Wang, Guangyao Wang, Qian Liu, Yingting Zuo, Shuohua Chen, Boni Tao, Xue Tian, Penglian Wang, Xia Meng, Shouling Wu, Yongjun Wang and Yilong Wang Tags: Original investigation Source Type: research

The association of the treatment with glucagon-like peptide-1 receptor agonist exenatide or insulin with cardiovascular outcomes in patients with type 2 diabetes: a retrospective observational study
Background: To evaluate the association of treatment with glucagon-like peptide-1 (GLP-1) receptor agonist exenatide and/or insulin on macrovascular outcomes in patients with type 2 diabetes (T2DM). Methods: We conducted a retrospective longitudinal pharmaco-epidemiological study using large ambulatory care data to evaluate the risks of heart failure (HF), myocardial infarction (MI) and stroke in established T2DM patients who received a first prescription of exenatide twice daily (EBID) or insulin between June 2005 and May 2009, with follow-up data available until December 2012. Three treatment groups were: EBID with oral ...
Source: Cardiovascular Diabetology - January 24, 2015 Category: Cardiology Authors: Sanjoy PaulKerenaftali KleinDavid MaggsJennie Best Source Type: research

Asymmetric dimethylarginine and long-term adverse cardiovascular events in patients with type 2 diabetes: relation with the glycemic control
Conclusions: In patients with type 2 diabetes, ADMA might be an independent risk factor for long-term adverse cardiovascular events. However, ADMA was not correlated with serum HbA1c level, and in diabetic patients with HbA1c ?6.5%, elevated ADMA level was no longer associated with increased risk of long-term prognosis. Our findings suggested that the prognosis predictive value of ADMA in type 2 diabetes might be modified by the glycemic control.
Source: Cardiovascular Diabetology - December 3, 2014 Category: Cardiology Authors: Chiao-Po HsuPai-Feng HsuMing-Yi ChungShing-Jong LinTse-Min Lu Source Type: research

Cardiovascular effects of Glucagon-like peptide 1 (GLP-1) receptor agonists
Patients with type 2 diabetes have a several-fold increased risk of developing cardiovascular disease when compared with nondiabetic controls. Myocardial infarction and stroke are responsible for 75% of all death in patients with diabetes, who present a 2-4x increased incidence of death from coronary artery disease. Patients with diabetes are considered for cardiovascular disease secondary prevention because their risk level is similar to that reported in patients without diabetes who have already suffered a myocardial infarction. More recently, with a better risk factors control, mainly in intensive LDL cholesterol target...
Source: Cardiovascular Diabetology - October 22, 2014 Category: Cardiology Authors: Francisco SaraivaAndrei Sposito Source Type: research

Relationship of obesity and insulin resistance with the cerebrovascular reactivity: a case control study
Conclusions: We found a diminished vasomotor reactivity in individuals with obesity which was not explained by the presence of insulin resistance.
Source: Cardiovascular Diabetology - January 3, 2014 Category: Cardiology Authors: Marcela Rodríguez-FloresCarlos Cantú-BritoEduardo García-GarcíaClaudia Cano-Nigenda Source Type: research

Diabetes severity and the role of leisure time physical exercise on cardiovascular mortality: the Nord-Trlatin small letter o with strokendelag Health study (HUNT), Norway
Conclusions: The data suggest a more favourable effect of exercise in people with diabetes who used medication than in those who did not, suggesting that physical exercise should be encouraged as a therapeutic measure additional to medical treatment.
Source: Cardiovascular Diabetology - June 6, 2013 Category: Cardiology Authors: Børge MoeLiv Berit AugestadTom Nilsen Source Type: research