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Infectious Disease: Malaria
Drug: Docetaxel
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Synthesis, characterization, molecular docking, antimalarial, and antiproliferative activities of benzyloxy-4-oxopyridin benzoate derivatives
CONCLUSION AND IMPLICATIONS: The compounds showed a moderate ability to inhibition of heme polymerization and also good interaction with heme through molecular docking was observed. Additionally, some of them have a good cytotoxic effect on the study2 cell line. So further study on these compounds can lead to compounds that can be considered as anti-malarial and/or anticancer agents.PMID:35531137 | PMC:PMC9075022 | DOI:10.4103/1735-5362.343079
Source: Cell Research - May 9, 2022 Category: Cytology Authors: Marjan Mohebi Neda Fayazi Somayeh Esmaeili Mahboubeh Rostami Fereshteh Bagheri Alireza Aliabadi Parvin Asadi Lotfollah Saghaie Source Type: research
