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Brazilian green propolis: A novel tool to improve the cytotoxic and immunomodulatory action of docetaxel on MCF-7 breast cancer cells and on women monocyte
Phytother Res. 2021 Dec 4. doi: 10.1002/ptr.7345. Online ahead of print.ABSTRACTDocetaxel (DTX) is used against breast cancer despite its side effects such as toxicity and immunosuppression. Here we investigated the cytotoxic and immunomodulatory effects of the ethanol solution extract of propolis (EEP) in combination with DTX on MCF-7 breast cancer cells and on women's monocyte. The cytotoxic potential of EEP + DTX was assessed by MTT assay and the type of tumor cell death was evaluated by flow cytometry. The effects of EEP + DTX on the migration and invasion of MCF-7 cells were analyzed. Cytokine production by monocytes ...
Source: Cell Research - December 4, 2021 Category: Cytology Authors: Eliza de Oliveira Cardoso Karina Basso Santiago Bruno Jos é Conti Fernanda Lopes Conte Karen Ingrid Tasca Graziela Gorete Romagnoli Marjorie de Assis Golim Cl áudia Aparecida Rainho Jairo Kenupp Bastos Jos é Maurício Sforcin Source Type: research
