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Propofol decreased the etomidate-induced myoclonus in adult patients: a meta-analysis and systematic review
CONCLUSIONS: The meta-analysis currently generates the evidence of combination of propofol with the dosage of 0.25-2 mg/kg and etomidate can alleviate the occurrence and severity of etomidate-induced myoclonus, with decreased incidence of postoperative nausea and vomiting (PONV) and comparative side effects of hemodynamic and respiratory depression of patients in comparison with etomidate alone.PMID:36876671 | DOI:10.26355/eurrev_202302_31366
Source: European Review for Medical and Pharmacological Sciences - March 6, 2023 Category: Drugs & Pharmacology Authors: Y Feng X-B Chen Y-L Zhang P Chang W-S Zhang Source Type: research

A systematic review of risk factors for postinduction hypotension in surgical patients undergoing general anesthesia
CONCLUSIONS: Aging, ASA III-V, emergency operation, low baseline blood volume, long-term intake of ACEI/ARB, propofol induction, and increasing fentanyl dosage are potential risk factors for PIH, while body weight gain is a protective factor. Based on the current evidence, it is difficult to determine whether baseline blood pressure or gender is associated with the development of PIH.PMID:34859868 | DOI:10.26355/eurrev_202111_27255
Source: European Review for Medical and Pharmacological Sciences - December 3, 2021 Category: Drugs & Pharmacology Authors: B Chen Q-Y Pang R An H-L Liu Source Type: research

Safety and efficacy of propofol alone or in combination with other agents for sedation of patients undergoing colonoscopy: an updated meta-analysis.
Authors: Zhang K, Xu H, Li HT Abstract The aim of this meta-analysis was to assess the efficacy and safety of propofol sedation for colonoscopy in comparison with traditional sedative agents. We performed a systematic search of PubMed, Embase, Scopus, Web of Science CENTRAL (Cochrane Central Register of Controlled Trials) and Google Scholar databases to identify eligible randomized controlled trials (RCTs) published before November 2019, and compared the effect of traditional sedative agents (TA) with the effect of propofol/propofol combined with TAs for routine colonoscopy. We included 22 eligible trials in our an...
Source: European Review for Medical and Pharmacological Sciences - May 7, 2020 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research

Propofol induces apoptosis of non-small cell lung cancer cells via ERK1/2-dependent upregulation of PUMA.
CONCLUSIONS: Propofol inhibits viability and induces apoptosis of A549 cells via an ERK1/2-dependent PUMA signaling. PMID: 30024623 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - July 20, 2018 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research

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