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Polysaccharides from Tetrastigma Hemsleyanum Diels et Gilg attenuate LPS-induced acute lung injury by modulating TLR4/COX-2/NF- κB signaling pathway
Biomed Pharmacother. 2022 Sep 28;155:113755. doi: 10.1016/j.biopha.2022.113755. Online ahead of print.ABSTRACTTetrastigma Hemsleyanum Diels et Gilg (Sanyeqing, SYQ), a traditional herb native to China, has been widely used in the treatment of inflammatory diseases, febrile convulsions and dysentery. Previous studies have demonstrated the hypoglycemic, anti-inflammatory and anti-pyretic effects of polysaccharides from SYQ (SYQP). However, the role of SYQP in acute lung injury (ALI) remained unknown. Our present study aimed to explore the protective effects of SYQP in ALI and explained its underlying mechanism. In vivo, Balb...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - October 1, 2022 Category: Drugs & Pharmacology Authors: Bixu Wang Yue Lin Mingyuan Zhou Siyu Fu Bingqi Zhu Yuchi Chen Zhishan Ding Fangmei Zhou Source Type: research