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Drug: Medroxyprogesterone
Procedure: Papanicolaou (Pap) Smear

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Physical examination prior to initiating hormonal contraception: a systematic review
Conclusions: Although women with breast cancer should not use hormonal contraceptives, there is little utility in screening prior to initiation, due to the low incidence of breast cancer and uncertain value of CBE among women of reproductive age. Two fair quality studies demonstrated no differences between women who did or did not undergo pelvic examination prior to initiating OCs or DMPA with respect to risk factors or clinical outcomes. In addition, pelvic examination is not likely to detect any conditions for which hormonal contraceptives would be unsafe.
Source: Contraception - November 2, 2012 Category: OBGYN Authors: Naomi K. Tepper, Kathryn M. Curtis, Maria W. Steenland, Polly A. Marchbanks Tags: Review Articles Source Type: research