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Women's Health Initiative clinical trials: potential interactive effect of calcium and vitamin D supplementation with hormonal therapy on cardiovascular disease
Conclusions: CaD did not consistently modify the effect of CEE therapy or CEE + MPA therapy on CVD events. However, the increased risk of stroke due to CEE therapy appears to be mitigated by CaD supplementation. In contrast, CaD supplementation did not influence the risk of stroke due to CEE + MPA.
Source: Menopause - August 1, 2019 Category: OBGYN Tags: Original Articles Source Type: research

Women's Health Initiative estrogen plus progestin clinical trial: a study that does not allow establishing relevant clinical risks
Conclusions: The differences in RMST for the outcomes of the WHI study are too small to establish clinical risks related to hormone therapy use.
Source: Menopause - December 1, 2015 Category: OBGYN Tags: Original Articles Source Type: research

Contraception and obesity.
Abstract The prevalence of obesity is increasing massively over several decades in industrialized countries. Obese women are sexually active but they use fewer contraceptive methods and are at high risk of unintended pregnancy. In addition, obesity is an important risk factor for venous thromboembolism events and arterial thrombosis (myocardial infarction and ischemic stroke). All of these data are to be considered in choosing a contraceptive method for obese women. Except depot medroxyprogesterone acetate injection, the progestin-only contraceptives (progestin only pills and etonogestrel subdermal implant) and th...
Source: Gynecologie, Obstetrique et Fertilite - October 30, 2015 Category: OBGYN Authors: Lobert M, Pigeyre M, Gronier H, Catteau-Jonard S, Robin G Tags: Gynecol Obstet Fertil Source Type: research

Contraception et obésité
Publication date: Available online 31 October 2015 Source:Gynécologie Obstétrique & Fertilité Author(s): M. Lobert, M. Pigeyre, H. Gronier, S. Catteau-Jonard, G. Robin La prévalence de l’obésité augmente massivement depuis plusieurs dizaines d’années dans les pays industrialisés. Les femmes obèses ont une activité sexuelle, non différente des femmes de poids normal, et bénéficieraient d’une couverture contraceptive moindre et d’un risque de grossesse non désirée plus élevé. En outre, l’obésité constitue un facteur de risque important d’accident thromboembolique veineux et arté...
Source: Gynecologie Obstetrique and Fertilite - November 5, 2015 Category: OBGYN Source Type: research